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Lingling Yang


Miller OH, Yang L*, Wang CC, Hargroder EA et al. GluN2B-containing NMDA receptors regulate depression-like behavior and are critical for the rapid antidepressant actions of ketamine. Elife 2014;3:e03581. (*co-first author)

Wang CC, Held RG, Chang SC, Yang L, Delpire E, Ghosh A, Hall BJ. A critical role for GluN2B-containing NMDA receptors in cortical development and function. Neuron 2011;72:789-805.

Yang L, Cranson D, and Trinkaus-Randall V. Cellular injury induces activation of MAPK via P2Y receptors. J Cell Biochem. 2004;91:938-950.

Lingling Yang, Ph.D.

Lingling Yang is a research scientist I at the Stanley Center for Psychiatric Research at the Broad Institute of MIT and Harvard, working under the direction of Jen Q. Pan. Yang uses biochemical and molecular biological imaging, as well as next-generation sequencing techniques, to interrogate the function and localization of T-type calcium channels. In addition, she is generating new mutant animals that recapitulate human mutations associated with schizophrenia and other psychiatric diseases for studying the mechanisms underlying these diseases.

Collaborating with a structural biology group at Harvard University, Yang also tries to get proteomic and structural information of the T-type calcium channel. Her goal is to generate novel therapeutic approaches for psychiatric diseases based on deep understanding of the disease mechanisms and the structural information.           

Prior to joining the Broad Institute in 2016, Yang completed her Ph.D. at Boston University. She subsequently undertook a postdoctoral fellowship at Louisiana State University Health Sciences Center and a postdoc associate position at Tulane University.

Contact Lingling Yang via email at

February 2018