Disease areas

Our community seeks to translate genetic, mechanistic, and cellular discoveries into deep biological knowledge of the roots of common and rare human diseases, and to use those insights to develop new diagnostic and therapeutic strategies for patients.

Broad scientists probe the mechanisms of cancer and apply this knowledge to enable precision cancer medicine.

Using machine learning, genetics, single cell biology, and more, researchers here aim to improve cardiovascular disease diagnosis and treatment.

Broad researchers study the cellular roles and physiological impacts of genes associated with type 2 diabetes, with an eye towards better patient care.

By studying how microbes and hosts interact, researchers across the institute are working to prevent and treat a wide range of infectious and inflammatory diseases.

Our scientists are cataloging the molecular causes of kidney diseases in order to develop mechanism-based treatments. 

Broad researchers explore how genetics influences body weight in order to identify promising targets for future obesity therapies.

We are committed to uncovering psychiatric, neurodevelopmental, and neurodegenerative disorders' molecular roots and turning those findings into new treatments.

Our scientists search for the risk factors underlying rare genetic diseases to help reveal their biological underpinnings and improve patients' lives.