Broad is accelerating discovery

At the Broad, breakthroughs in AI converge with cutting-edge biomedicine to drive advances in both fields.

We are fostering a diverse research community engaged in innovative chemical biology and therapeutic research.

Our scientists are charting the vast landscape of molecular elements that define and regulate the cell.

Researchers across Broad are defining the immune cells and pathways that regulate physiologic and pathologic processes.

An array of scientists here are collaborating to establish genomic variations' roles in human traits and disorders.

Our researchers aim to decipher the metabolic basis of rare and common human diseases.

We are characterizing the genetic and mechanistic basis of brain health and brain diseases.

Our scientists are probing the mechanisms of cancer and applying this knowledge to enable precision cancer medicine.

By applying a variety of tools and technologies, researchers here are working to reduce the burden of cardiovascular disease.

By uncovering the biology underlying heart disease, diabetes, cancer, and more, we’re helping to develop effective new treatments that target the root causes of these chronic diseases. 

Our researchers study the cellular roles and physiological impacts of genes associated with type 2 diabetes.

Researchers across the institute are working to understand infectious diseases, antibiotic resistance, and the human microbiome.

Our scientists are cataloging the molecular causes of kidney diseases in order to develop mechanism-based treatments.

By studying the genetic determinants of body weight, our researchers work to identify targets for future obesity therapies.

Our scientists search for the risk factors underlying rare genetic diseases to help reveal their biological underpinnings and improve patients' lives.

Members of the Data Sciences Platform build open-source technologies that help researchers everywhere connect to the patients, datasets, and tools they need to do life-changing science.

Our Center for the Development of Therapeutics (CDoT) helps scientists advance biological insights to new treatments.

The Genetic Perturbation Platform drives the functional study of the genome by developing groundbreaking technologies for perturbing genes at scale.

Genomic scientists here at Broad create foundational resources and study the genomic basis of human traits and diseases.

Computationally mining cellular images' rich information content can propel discoveries in biology and medicine.

Cells' metabolites reveal unique chemical fingerprints of both normal and pathological disease processes.

Broad proteomic researchers address important questions in biology, chemistry, and clinical science through collaboration and technology development.

The Spatial Technology Platform expands the impact of spatial -omics through comprehensive support – from study design to data acquisition and processing – for a broad range of users. We also maintain an active research arm that develops and advances cutting edge spatial, imaging, and computational technologies.

Through innovative technologies, foundational resources, and breakthrough discoveries, Broad scientists are addressing important questions in human biology, health, and disease. See how our science has evolved.

Search a comprehensive list of all scientific papers published by Broad scientists over the years.