Genomics
The Genomics Platform has a 30-year track record of delivering on transformative projects in the field of genomics. Our goal has been two-fold: to create foundational genomics resources and capabilities for the community, and to undertake large-scale disease-based projects that pioneer approaches and advance the understanding of the genomic basis of disease and other traits.
Since the Human Genome Project in the 1990s, the Broad Genomics Platform has played a leadership role in the design, data generation, and methods development in support of major genomic resource projects including:
- the HapMap
- the 1000 Genomes Project
- The Cancer Genome Atlas (TCGA)
- Comparative Reference Genomes
- ENCODE
- the Genotype-tissue Expression Project (GTEx)
- the Human Microbiome Project
- the Exome Sequencing Program Center for Mendelian Genomics
- the Human Cell Atlas (HCA)
- the Exome Aggregation Consortium (ExAC) and Genome Aggregation Database (gnomAD) projects
- All Of Us
Over the past ten years, The Genomics Platform has been the largest producer of human genomic information in the world. Currently, the group produces approximately 500 terabases of genomic data per month — a rate equivalent to one 30X human whole genome every 10 minutes. The group has processed more than 2 million samples from more than 1,400 groups in more than 50 countries.
The Genomics Platform is comprised of approximately 150 people across several functional groups:
- Alliance and Project Management
- Analytics, LIMS, and Data Visualization
- Clinical Research Sequencing
- Genomic Analysis
- Lab Operations
- Research and Development
- Robotics and Automation
- Services (fee for service)
- Walk Up Sequencing
The platform provides a range of services — including CAP-accredited and CLIA-certified genomic data generation and advanced genomic analysis — both for the Broad research community and through a fee-for-service model.
