By analyzing bacterial data, researchers have discovered thousands of rare new CRISPR systems that have a range of functions and could enable gene editing, diagnostics, and more.
A one-time genome-editing treatment restores motor function and extends lifespan in an animal model of a neuromuscular disease that is the leading genetic cause of infant mortality.
Scientists have solved the structure of an important complex of RAS-pathway proteins, explaining how known mutations lead to disease and suggesting potential new binding sites for cancer drugs.
By studying individual cardiac cells from heart failure patients, researchers have identified molecular signatures that point to biological mechanisms of disease.
International collaborations analyze common and rare DNA variants in hundreds of thousands of people, further elucidating genetic roots of psychiatric disorder
Researchers will analyze the DNA of tens of thousands of people from five countries in East and South Asia to find genetic markers for the psychiatric condition.
A study of respiratory syncytial virus genomes reveals that multiple lineages were circulating within the United States last fall, rather than one highly transmissible variant.
Broad researchers discover that changes in immune responses and the gut microbial community could underlie repeated occurrences of these common infections.
By introducing cancer-causing mutations into healthy skin cells step-by-step, Broad scientists have created models of skin cancer that can reveal the effects of mutations.
Count Me In (CMI), an initiative focused on patient-partnered cancer research, has announced the launch of a new cohort for individuals with hepatocellular carcinoma (HCC) and HCC-like tumors.
Just a few weeks into his new position, Kedrick Perry spoke about his approach to diversity, equity, inclusion, and belonging, what his goals are, and what motivates him in his work.
Analysis of more than 314,000 cells from rheumatoid arthritis tissue defines six types of inflammation involving diverse cell types and disease pathways