Breadcrumb Home Vector Engineering Vector Engineering Publications Zelikowsky, M., Hui, M., Karigo, T., Choe, A., Yang, B., Blanco, M.R., Beadle, K., Gradinaru, V., Deverman, B.E., and Anderson, D.J. The Neuropeptide Tac2 Controls a Distributed Brain State Induced by Chronic Social Isolation Stress. Cell, 2018. DOI:10.1016/j.cell.2018.03.037. Bedbrook CN, Deverman BE, Gradinaru V. Viral strategies for targeting the central and peripheral nervous systems. Annual Review of Neuroscience 2018. DOI: 10.1146/annurev-neuro-080317-062048. Challis RC, Ravindra Kumar S, Chan KY, Challis C, Jang MJ, Rajendran PS, Tompkins JD, Shivkumar K, Deverman BE, Gradinaru V. Widespread and targeted gene expression by systemic AAV vectors: Production, purification, and administration. Preprint on bioRxiv. DOI: 10.1101/246405 Chan KY, Jang MJ, Yoo BB, Greenbaum A, Ravi N, Wu WL, Sanchez-Guardado L, Lois C, Mazmanian SK, Deverman BE, Gradinaru V. Engineered AAVs for efficient noninvasive gene delivery to the central and peripheral nervous systems. Nature Neuroscience 2017. DOI: 10.1038/nn.4593 Allen WE, Kauvar IV, Chen MZ, Richman EB, Yang SJ, Chan K, Gradinaru V, Deverman BE, Luo L, Deisseroth K. Global representations of goal-directed behavior in distinct cell types of mouse neocortex. Neuron 2017. DOI: 10.1016/j.neuron.2017.04.017 Deverman BE, Pravdo PL, Simpson BP, Kumar SR, Chan KY, Banerjee A, Wu WL, Yang B, Huber N, Pasca SP, Gradinaru V. Cre-dependent selection yields AAV variants for widespread gene transfer to the adult brain. Nature Biotechnology 2016. DOI: 10.1038/nbt.3440 Vector Engineering About Team Research Publications Latest news News 08.12.2026 AI model streamlines prime editing News 08.10.2026 New effort launches at Broad to accelerate translation of genetics to therapies News 08.05.2026 Cancer Dependency Map now includes next-generation 3D cancer models News 07.23.2026 Combining AI with laboratory evolution yields improved proteins All news