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PI keywords Diseases, research area Methods Category Description
Ben Neale genetics, computational, statistics, large-scale, complex,epidemiology, variants, data, analysis Bipolar disorder, schizophrenia, ADHD, autism development and application of statistical methods Genetics Director of Genetics, interrogating both common and rare genetic background of bipolar disorder and schizophrenia
Mark Daly (MGH)   schizophrenia, autism, and ADHD development and application of statistical methods Genetics Founding member of Stanley Center. He studies the genetics of numerous common diseases, particularly neuropsychiatric genetics especially schizophrenia, autism, and ADHD.
Karestan Koenen (HSPH) genetics, diversity, neuropsychiatric, PTSD, trauma, statistics, epidemiology, variants, mental health, data, analysis PTSD, Trauma, development and application of statistical methods Genetics Leads the Global Neuropsychiatric Genomics Initiative, as well as the NeuroGAP and NeuroMex programs which aim to conduct collaborative neuropsychiatric genetics research and capacity building in historically underrepresented populations in Africa and Mexico. Now establishing the Biology of Trauma Initiative.
Alicia Martin (MGH) genetics, diversity, evolution, ancestry, large-scale, population genetics, neuropsychiatric, heritable, data, analysis psychatric disorders statistical methods, community resources for genomics, and research capacity for multi-ancestry studies Genetics Studies the heritable basis of psychiatric disorders in diverse populations. Developing statistical methods, community resources for genomics, and research capacity for multi-ancestry studies particularly in underrepresented populations.
Aarno Palotie (MGH)   Schizophrenia, psychosis, migraine, epilepsy, development and application of statistical methods Genetics Focus on working with the unique clinical and population based samples from the Finnish founder population including the genetics of Schizophrenia. Lead PI on the SUPER collection of 10,000 individuals with psychosis.
Elise Robinson (HSPH)   neurodevelopment disorders statistical genetics and epidemiology Genetics Her lab uses genetic data to understand the biological basis of neurodevelopmental disorders. She oversees the NeuroDev project within the Stanley Center, and co-leads the Neurodevelopmental Variability (NDV) Initiative with Mike Talkowski.
Michael Talkowski (MGH)   Autism, autism related neurodevelopmental disorders gene discovery efforts and cellular modeling Neurobiology He studies the genetic etiology of complex developmental and neuropsychiatric disorders. He has led large-scale gene discovery efforts and cellular modeling studies in autism and related neurodevelopmental disorders. Co-leads the Neurodevelopmental Variability (NDV) Initiative with Elise Robinson.
Paola Arlotta (Harvard), Director, Cellular Models, Stanley Center neurobiology, stem cells, organoids, neurons, in vitro, brain, cell types, molecular, cellular Human cortical development, neurodevelopmental diesease stem cell-derived brain organoids Neurobiology Her lab focuses on the development of new high-throughput in vitro models of human cortical development and neurodevelopmental disease using 3D cerebral organoids.
Guoping Feng (MIT), Director, Model Systems and Neurobiology, Stanley Center   synapse function and disruption genetic tools, behavioral and electrophysiological methods Neurobiology Director model systems and neurobiology. His research focuses on the function of synapses and their disruption in animal models (especially non human primate models) of neurodevelopmental and psychiatric disease.
Steve McCarroll (HMS), Director, Genomic Neurobiology, Stanley Center genetics, computational, neurobiology, cell types, sequencing, genome, variation, tools, single cell, data Schizophrenia single-cell analysis Neurobiology Director of Genomic Neurobiology. His lab hopes to uncover the key molecular and cellular events in the development of schizophrenia and other brain illnesses using approaches for single-cell analysis. Co-lead PI on a new NIH-funded project to create an atlas of variation in human brain cells.
Beth Stevens (CH), Director, Neuroimmunology, Stanley Center   synapse disappearance immune related molecules Neurobiology Director of neuroimmunology. Her research seeks to understand the mechanisms that regulate the disappearance of synapses — junctions where nerves communicate with each other — by focusing on how immune-related molecules mediate this process.
Ben Deverman (Broad), Director, Viral Vector Engineering, Stanley Center   CNS gene delivery, computatational Neurobiology Director of Viral Vector Engineering Program. His lab studies gene delivery solutions with the aim of uncovering new avenues for treating psychiatric disorders.
Randy Buckner (Harvard)   Schizophrenia behaviour, neuroimaging, computational Neurobiology PI involved with the Schizophrenia Spectrum Biomarkers Consortium. His research uses multiple behavioral, neuroimaging and computational approaches to characterize brain networks and how variation gives rise to differences in network organization and behavior, including dysfunction in neuropsychiatric illness.
Adam Cohen (Harvard)   nervous system optics, protein engineering, chemistry, electrophysiology, simulation, and theory Neurobiology His lab developed fluorescent voltage-indicating proteins which enable optical mapping of neural activity. These tools have opened the door to all-optical electrophysiology and to large-scale mapping of brain activity.
Gordon Fishell (HMS)   cerebral cortex molecular methods Neurobiology His lab studies the cerebral cortex, and the formation, function, and dysfunction of interneurons and synapses.
Kasper Lage (MGH)   brain networks genomic and computational approaches Neurobiology His lab combines genetic discoveries with proteomics to determine the brain networks of physically interacting proteins that are perturbed in neuropsychiatric disorders.
Evan Macosko (HMS)   novel cell populations molecular biology, microfluidics, and organic chemistry Neurobiology His research develops new genomic technologies to identify how each cell type contributes to brain function and where each gene acts. Co-lead PI on a new project to create an atlas of variation in human brain cells with Steve McCarroll.
Bernardo Sabatini (HMS)   synapse and circuit plasticity optical, electrophysiological, and behavioral approaches Neurobiology His lab uses high-throughput methods for characterizing local and long-range brain circuits, mechanisms of synapse and circuit plasticity


 

PI keywords Diseases, research area Methods Category
Ben Neale
Director of Genetics, interrogating both common and rare genetic background of bipolar disorder and schizophrenia
epidemiology  Bipolar disorder, schizophrenia, ADHD, autism development and application of statistical methods Genetics
Ben Neale
Director of Genetics, interrogating both common and rare genetic background of bipolar disorder and schizophrenia
genetics Bipolar disorder, schizophrenia, ADHD, autism development and application of statistical methods Genetics
Ben Neale
Director of Genetics, interrogating both common and rare genetic background of bipolar disorder and schizophrenia
computational Bipolar disorder, schizophrenia, ADHD, autism development and application of statistical methods Genetics
Mark Daly (MGH)
Founding member of Stanley Center. He studies the genetics of numerous common diseases, particularly neuropsychiatric genetics especially schizophrenia, autism, and ADHD.
genetics schizophrenia, autism, and ADHD development and application of statistical methods Genetics
Ben Neale
Director of Genetics, interrogating both common and rare genetic background of bipolar disorder and schizophrenia
statistics development and application of statistical methods Genetics