Five questions

  • Five Questions for Feng Zhang

    Veronica Meade-Kelly, September 17th, 2013 | Filed under

    Core faculty member Feng Zhang, who joined the Broad in 2011, has quickly earned a reputation as one of the brightest young scientists working today. His research on optogenetics and genome engineering earned him a spot in this year’s “Brilliant 10,” Popular Science magazine's annual list of the most promising scientific innovators.

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  • Five Questions for Sangeeta Bhatia

    Leah Eisenstadt, August 15th, 2013 | Filed under

    For Sangeeta Bhatia, now is an exciting time to be a biomedical engineer. Her research on liver regeneration and nanomedicine spans the diverse and quickly advancing fields of nanotechnology, regenerative medicine, infectious disease, cancer, and tissue engineering, among others.

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  • Five Questions for Dawn Thompson

    Veronica Meade-Kelly, June 21st, 2013 | Filed under

    Dawn Thompson has spent much of her career studying yeast. The experimental biologist, who is assistant director of the Broad’s Cell Circuits Program, and group leader in core member Aviv Regev’s lab says that she fell into the field “by accident.” While interviewing for her first post-college research position, she happened to hit it off with a yeast geneticist. After working in that lab, she went on to graduate school.

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  • Five questions for Steven Hyman

    Elizabeth Cooney, September 1st, 2011 | Filed under

    Steven E. Hyman is intent on reinventing himself in a place that welcomes creativity.

    Former provost of Harvard University and before that, director of the National Institute of Mental Health (NIMH), the Harvard University professor of stem cell and regenerative biology began a one-year sabbatical at the Broad Institute in July. He is a scholar in residence at the Stanley Center for Psychiatric Research within the Broad’s Psychiatric Disease Program.

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  • Five questions for Martin Leach

    Haley Bridger, August 12th, 2011 | Filed under

    At the Broad, collaboration is king. But in order to share ideas and data, scientists need a robust infrastructure that can support the volume and speed at which results are produced. That’s where Chief Information Officer Martin Leach and his team of experts in information technology and research computing come in. Their goal is to provide the software and technology that will enable the best collaboration experience, which will in turn accelerate groundbreaking science to transform medicine.

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  • Five questions for Ramnik Xavier

    Elizabeth Cooney, June 8th, 2011 | Filed under

    Ramnik Xavier calls it “learning from human genetics.” That’s how the senior associate member of the Broad Institute describes his research building on the soaring number of genes now known to be implicated in two common disorders, Crohn’s disease and type 1 diabetes.

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  • Five Questions for Matthew Meyerson

    Haley Bridger, January 18th, 2011 | Filed under

    Senior associate member Matthew Meyerson recalls the line that opens the novel Anna Karenina: “Happy families are all alike; every unhappy family is unhappy in its own way.” Just like unhappy families, every cancer genome that he and his colleagues study is abnormal in its own way. But by looking across cancer samples and cancer types, researchers are beginning to appreciate cancer’s patterns of convergence.

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  • Five Questions for Stanley Shaw

    Alice McCarthy, January 13th, 2011 | Filed under

    Part of what we do at the Broad involves unraveling the genomes of humans, dogs, and dozens of other creatures as part of a larger mission to improve human health. In addition to finding genes or mutations linked with disease, Broad scientists seek to learn what the genes are doing functionally, and how to use that information to devise new therapies.

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  • Five Questions for Anna Mandinova and Sam Lee

    Alice McCarthy, January 6th, 2011 | Filed under

    In a paper published January 5, 2011 in Science Translational Medicine, Anna Mandinova and Sam Lee, both researchers at Massachusetts General Hospital and associate members of the Broad, describe the obstacles and promise of developing small compounds that target the p53 pathway, the most common pathway involved in cancer. I asked them both to discuss the challenges of finding p53-targeted molecules and the approaches they are currently working on.

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  • Five Questions for Manolis Kellis

    Haley Bridger, December 23rd, 2010 | Filed under

    If you were to plot out the locations of the approximately 23,000 genes that make us human, our genome would look like a vast desert, dotted with rare gene oases. The ENCODE Project aims to map these supposed genetic wastelands, which upon closer examination, harbor critical genomic machinery. These signals are encoded in diverse functional genomic elements that determine, among their many other functions, how and when genes are turned on and turned off.

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