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MIA Talks

Machine-learning-based CRISPR guide design

November 15, 2017
Microsoft Research

Effective guide design is a key part of CRISPR-Cas9 deployment. Although molecular biology is working to improve CRISPR-Cas9 and related systems, one can make the guide design process more effective by using machine learning. We will discuss our state-of-the-art machine-learning based guide design models for both on-target (Azimuth) and off-target (Elevation) prediction.