2015 Research Highlights
Matthew Aguirre, a junior applied math concentrator at Harvard College
Worked to develop a cellular model of limb-girdle muscular dystrophy (LGMD) patient mutations.
Miranda Barraza, a junior human biology major at the University of California, San Diego
Characterized the expression and developmental profile of the schizophrenia-associated Cav3.3 gene in mouse brain tissues.
Jake Bieber, a junior chemical and biomolecular engineering major at Johns Hopkins University
Studied rhabdoid tumors’ susceptibility to treatment with RTK inhibitors.
Justin Chávez, a junior at the University of Maryland, Baltimore County majoring in bioinformatics and computational biology
Investigated possible synthetic lethal gene interactions in breast cancer cells and built components for a bioreactor, known as “mutatostat,” that adjusts mutation rate to determine interactions relevant to an antibiotic resistance model.
Tendai Chisowa, a senior biology and chemistry major at Williams College
Researched the modulation of the schizophrenia associated gene, GRIA1, by the CUL3 ubiquitin ligase.
Christopher Dunlock, a senior biochemistry major at Xavier University of Louisiana
Investigated how single cell heterogeneity impacts the Candida albicans–macrophage interface.
Shylee Ezroni, a third year applied mathematics major at Wentworth Institute of Technology
Identified gene expression features to distinguish SNPs causative of disease.
Tory Govan, a junior biology major at Northeastern University
Assisted in generating the next generation of prostate cancer cell model.
Dominic Gray, an applied mathematics junior at Norfolk State University
Used SNP genotyping data to develop a tool improving detection of recent common ancestry among malaria parasite populations.
Jada Kline, a junior biology and political science major at the University of Wisconsin-Madison
Investigated the protein S100A7 by analyzing which of its amino acids are critical for receptor binding.
Maximillian Marin, a junior studying biochemistry and molecular biology at University of California, Santa Cruz
Investigated the differential splicing and expression of the MUC1 gene in human tissues.
Bethany Smith, a junior biochemistry and genetics double major at Texas A&M University
Worked on optimizing a pooled barcode cloning methodology to study cancer metastatic potential in vivo.
News at the broad
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