Farhi group

Research in our lab focuses on pushing the boundary of imaging technologies, seeking ever more comprehensive and multi-modal portraits of biological systems.

The links below describe some ongoing projects.  


Lipinski group

Michal Lipinski leads the sequencing-based spatial transcriptomics team within the Spatial Technology Platform. This group focuses on exploring the technological boundaries of the sequencing-based methods and applying them in unique ways to discover novel biology. Michal’s particular interest lies in understanding psychiatric and nervous system disorders by utilizing stem cell models and intact human tissue. These approaches, coupled with next-generation methods for evaluating drugs in the lab, hold promise for accelerating drug discovery and precision medicine.


Fernandez group

Nicolas Fernandez leads the computational team within the Spatial Technology Platform. Our team is focused on developing tools and best practices for researchers to extract biological insights from single-cell spatial multi-omics data. Nicolas’ research interests include tissue organization, the tumor-immune microenvironment, and developing multimodal spatial analysis/visualization approaches. Nicolas joined the Broad institute in December 2023 and has previously worked as a computational biologist in academia and industry after completing his Ph.D in Biomedical Sciences from Albert Einstein College of Medicine.


Erion-Barner group

Lindsey Erion-Barner leads the imaging-based spatial transcriptomics team within the Spatial Technology Platform. This group focuses on developing novel approaches for high-throughput and 3D imaging transcriptomics, as well as multi-omic approaches that combine protein labeling and imaging transcriptomics. Additionally, her team is developing optogenetic approaches for investigating mechanisms of psychiatric diseases in collaboration with the Granger group. Her research interests include leveraging and developing new light sheet microscopy techniques for multiplexed 3D transcriptomics and high-throughput imaging methods for multi-omics, as well as 3D imaging techniques for pathology applications.