DLBCL Genome Sequencing

To gain insight into the genomic basis of diffuse large B-cell lymphoma (DLBCL), we performed massively parallel whole-exome sequencing of 55 primary tumor samples from patients with DLBCL and matched normal tissue. We identified recurrent mutations in genes that are likely to play a role in the biology of DLBCL.

Contact: 
Jens Lohr jenslohr@broadinstitute.org
Data Info: 
Description: 

Here is the link to the DLBCL sequencing data in dbGAP.

Publication Info: 
Date: 
3/6/2012
Notes: 
Lohr, el al. Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing. Proc Natl Acad Sci U S A. 2012 Mar 6;109(10):3879-84. Epub 2012 Feb 17.