Achilles Project

The goal of the Achilles Project is to create a genome-wide catalog of tumor dependencies to identify vulnerabilities associated with genetic or epigenetic alterations.

Paquita Vazquez
Data Info: 

The Project Achilles data is hosted on the new Project Achilles Data Portal.
Here, you can find the Project Achilles data as well as links to files that include annotation information. You can also find links that provide information about the processing of the data files. For additional informaiton about many of the cell lines, please visit the Cancer Cell Line Encyclopedia portal.

Publication Info: 
Cheung, et al. Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer. Proc Natl Acad Sci U S A. 2011 Jul 26;108(30):12372-7. Epub 2011 Jul 11.
Tool Info: 

Links to GenePattern modules and tutorials forĀ Achilles 2 data analysis.