The Cancer Therapeutics Response Portal (CTRP) links genetic, lineage, and other cellular features of cancer cell lines to small-molecule sensitivity with the goal of accelerating discovery of patient-matched cancer therapeutics. CTRP can be mined to develop insights into small-molecule mechanisms of action and novel therapeutic hypotheses, and to support future discovery of drugs matched to patients based on predictive biomarkers.

Publications

https://www.ncbi.nlm.nih.gov/pubmed/23993102
https://www.ncbi.nlm.nih.gov/pubmed/25058389
https://www.ncbi.nlm.nih.gov/pubmed/26482930
https://www.ncbi.nlm.nih.gov/pubmed/26656090
https://www.ncbi.nlm.nih.gov/pubmed/28678785

cell line profiling

Topic
Cancer
cell line profiling
Portals
small molecules
Therapeutic Response