Primer on Medical and Population Genetics

The Primer on Medical and Population Genetics is a series of informal weekly lectures on basic genetics topics that relate to human populations and disease. Experts from across the Medical and Population Genetics community at the Broad Institute give in-depth introductions to the basic principles of human genetics, including genetic variation, genomic methods, statistics, data analysis, genomic interpretation, tool tutorials and more.

Videos of these sessions are made freely available for viewing here and are geared toward a wide audience that includes research technicians, graduate students, postdoctoral fellows, and established investigators just entering the field. Videos are also available for streaming at the Broad's YouTube channel.

If you'd like more information about the primers or have suggestions for future topics, contact seminar series organizers Sarah Morton and Diane Genereux.

2020 - 2021 Primers
9/17/20 A History of Eugenics
[ video ]
Robbee Wedow
Stanley Center
Broad Institute
9/24/20 RNA Product Offerings by the Genomics Platform
[ video ]
Caroline Petersen and Cole Walsh
Genomics Platform
Broad Institute
10/1/20 A Practical Guide To Differential Gene Expression and Pathway Analysis
[ video ]
Amelia Hall
Broad Institute
10/8/20 Using tximport and DEseq2 to identify differentially expressed genes: Terra tutorial
[ video ]
Amelia Hall
Broad Institute
10/15/20 scRNA-seq analyses: challenges, opportunities, and best practices - Part 1
[ video ]
Stephen Fleming
Broad Institute
10/22/20 Integration of RNA-seq and chromatin accessibly for genome-wide expression analysis
[ video ]
Lauren Wasson 
Seidman Lab
Broad Institute
11/5/20 scRNA-seq analyses: challenges, opportunities, and best practices - Part 2
[ video ]
Stephen Fleming
Broad Institute
11/12/20 How to scale up GWAS to maximize power: successes & failures
[ video ]
Chris Newton-Cheh
Broad Institute
12/4/20 The A to Z of Project Management
[ video ]
Namrata Gupta
Broad Institute
1/7/21 The Baby-Seq Project - Special considerations for enrollment and consent
[ video ]
Casie Genetti
Boston Children's Hospital
1/21/21 Introduction to expression quantitative trait loci
[ video ]
Francis Auget
Broad Institute
2/4/21 Temporal Dynamics of RNA expression
[ video ]
Sophia Liu
Broad Institute
2/22/21 The Zoonomia Project
[ video ]
Diane Genereux
Broad Institute
3/4/21 Introduction to Pharmacogenetics
[ video ]
Josephine Li
Broad Institute
3/11/21 Introduction to Genetic Counseling: at the Broad and Beyond
[ video ]
Samantha Baxter and Danielle Azzariti
Broad Institute
3/18/21 Ethics in Ancient DNA research
[ video ]
Jakob Sedig
Reich Laboratory
Broad Institute
4/1/21 Ten years of variant discovery in the 1000 Genomes Project
[ video ]
Xuefang Zhao
Talkowski Laboratory
Broad Institute
4/8/21 Variant Classification using ACMG/AMP Interpreting Sequence Guidelines
[ video ]
Steven Harrison
Genomics Platform
Broad Institute
4/15/21 The Knowledge Portal Network
[ video ]
Maria Costanzo
Broad Institute
4/29/21 Gene-environmental Interactions
[ video ]
Kenny Westerman
Manning Laboratory
MGH/Broad Institute
6/1/21 Population differentiation and admixture of domestic dog breeds
[ video ]
Kathleen Morrill
Broad Institute
6/24/21 Introduction to Perturb-seq analysis
[ video ]
Ayshwarya Subramanian
Broad Institute