Publications

Ren J-G, Seth P, Everett P, Clish CB, Sukhatme VP. Induction of Erythroid Differentiation in K562 Erythroleukemia Cells by Depletion of Malic Enzyme 2. PLoS ONE 2010; in press.

Düvel K, Yecies JL, Raman P, Menon S, Lipovsky AI, Souza AL, Triantafellow E, Ma Q, Gorski R, Cleaver S, Vander Heiden MG, MacKeigan JP, Finan PM, Clish CB, Murphy LO, Manning BD. Activation of a metabolic gene regulatory network downstream of mTORC1. Mol Cell 2010; in press

Lewis GD, Farrell L, Martinovic M, Arany Z, Rowe GC, Souza A, Cheng S, McCabe EL, Yang E, Shi X, Deo R, Roth FP, Asnani A, Rhee E, Systrom DM, Semigran MJ, Vasan RS, Carr SA, Wood MJ, Wang TJ, Sabatine MS, Clish CB, Gerszten RE. Novel Metabolic Signatures of Exercise in Human Plasma. Sci Transl Med 2010; 2:33ra37.

Rhee E, Souza A, Farrell L, Pollak M, Steele D, Thadhani R, Clish CB, Greka A, Gerszten R. Metabolite Profiling Identifies Novel Markers of Uremia and the Hemodialysis Procedure. J Am Soc Nephrol 2010; 21:1041-1051.

Gohil VM, Sheth SA, Nilsson R, Wojtovich AP, Lee JH, Perocchi F, Chen W, Clish CB, Ayata C, Brookes PS, Mootha VK. Discovery and therapeutic potential of drugs that shift energy metabolism from mitochondrial respiration to glycolysis. Nat Biotechnol 2010; 28:249-55. PMCID: PMC2824369

Zhong L, D'Urso A, Toiber D, Sebastian C, Henry R, Vadysirisack DD, Guimaraes A, Marinelli B, Wikstrom J, Nir T, Clish C, Vaitheesvaran B, Kurland I, Dor Y, Weissleder R, Shirihai O, Ellisen L, Espinosa J, Mostoslavsky R. The Histone Deacetylase SIRT6 is a Master Regulator of Glucose Homeostasis. Cell 2010; 140:280-293.

Shaham O, Slate NG, Goldberger O, Xu Q, Ramanathan A, Souza AL, Clish CB, Sims KB, Mootha VK. A plasma signature of human mitochondrial disease revealed through metabolic profiling of spent media from cultured muscle cells. Proc Nat Acad Sci USA 2010; 107:1571-5.