#HowWeScience
At the Broad Institute, researchers are revealing deep biological insights about the causes of disease, which are leading to new ways to monitor, diagnose, and treat patients with greater precision. These include new tools that help predict diseases well before symptoms appear, and more effective therapeutics that reduce the chance of relapse or drug resistance.
Illuminating human disease
Cataloging the genetic adaptations that cancer cells rely on and leveraging them to develop new treatments
Using genomics to understand and track the spread of pathogens, and bring them under control.
Exploring the genetic origins of Crohn’s disease, ulcerative colitis, and related diseases to better prevent and treat them
Psychiatric disorders
Charting a path to new therapies by unraveling the genes and mechanisms that drive psychiatric disease
Developing and using computational tools to detect subtle patterns in biomedical data.
Reading and editing genomes
Discovering how thousands of tiny genetic alterations lead to disease
Creating foundational genomics resources and capabilities to understand health and disease
A comprehensive reference map of all human cells as a basis for understanding human health and disease
Developing diagnostics and treatments
Enabling clinicians to monitor the progress of a patient’s cancer through blood samples, rather than invasive procedures
Ensuring the SHERLOCK diagnostic platform is easily accessible, especially in the developing world, where the need for inexpensive, reliable, field-based diagnostics is the most urgent
Predicting a person’s genetic risk for many common diseases by scanning subtle variants across the genome
Sharing data and tools to enable discovery
Uniting sequencing data from large-scale projects and making it available to the scientific community
Partnering with technology leaders to make Broad data and tools available to researchers across the globe on secure, cloud storage platforms
Building open and scalable data-science tools to advance biomedical research
Data generated from studying trillions of cells are open and accessible to researchers worldwide.
Making science available to the world to maximize public benefit
Building communities
Collaborating internationally to create standards to effectively store, share, analyze, and protect genomic and clinical data
A global consortium of thousands of scientists is building a complete reference map of all human cells.
Working with patients with cancer, rare diseases, and other conditions to accelerate the pace of discovery and find better treatments
Collaborating, innovating, and empowering
Bringing together some of the most talented physicians, biomedical researchers, data scientists, software engineers, and more to address the most urgent and ambitious scientific challenges in human health.
Bridging academia and industry to translate discoveries into therapeutics that benefit patients
