Science for All Seasons gives you a chance to explore hot topics in genomics with leading experts from the Broad Institute. Find out what key advances, new technologies, and the latest findings mean for you in this free and open lecture series.
The genome encodes the basic blueprints and switches underlying everything a cell does, but it's the proteome — the cell's collection of proteins — that does the work of carrying signals, turning circuits on and off, processing energy, and more. How do researchers study the proteome, and how does that knowledge translate into new approaches to treating disease? Research scientist Namrata Udeshi and physician-scientist Michael Gillette will take us on a tour of the proteome and discuss some of the opportunities that the science of proteomics presents for advancing human health.
The human genome is huge — more than three billion As, Cs, Ts, and Gs strung together and packaged into 23 chromosomes. But even with the biotech advances of the last 20 years, its workings remain mostly a mystery.
The Zoonomia Project is comparing hundreds of species' genomes to investigate genome function. We are finding that some parts of the genome are so important that they are identical among species separated by millions of years of evolution, while others are uniquely human. By discovering the genomic secrets of species that perform incredible feats of physiology — such as hibernating ground squirrels that go months without eating, and deep-diving seals that endure minutes without breathing — we are using evolutionary history to help inform the next generation of therapeutics.
Genome biologists Elinor Karlsson and Diane Genereux will describe how comparative genomics is shaping our understanding of human health and, in the process, supporting efforts to protect species at risk of extinction.