The RNAi Consortium, or TRC, is a public-private effort based at the Broad whose mission is to create a shRNA library as well to validate tools and methods that will enable the scientific community to use RNAi to determine the function of human and mouse genes. The reagents are composed of short hairpin sequences carried in lentiviral vectors arrayed in 96-well plates.
Library Distribution
The TRC shRNA library is distributed as bacterial glycerol stocks, plasmid DNA or lentiviral particles by Sigma-Aldrich and as bacterial glycerol stocks by Open Biosystems. The Broad RNAi platform does not directly distribute the TRC library.