Research Highlights:
Schizophrenia

Schizophrenia is a highly heritable psychiatric disorder characterized by hallucinations, emotional withdrawal, and a decline in cognitive function. Over the past six decades, there has been little innovation in drug development for the disorder, which afflicts roughly one percent of all adults, and currently available medications address only one of the symptoms (psychosis), not the more debilitating cognitive impairments. The molecular and cellular underpinnings of schizophrenia have not been well understood. There are no good models of schizophrenia in cells, animals, or human tissues, so traditional scientific approaches can’t be used to illuminate the disorder.