Reading and editing biology
New technologies for reading and editing DNA and RNA provide vast amounts of data and reveal transformative insights. At the Broad Institute, scientists generate a whole human genome’s worth of genetic data every few minutes, read gene expression patterns in tissues and in millions of single cells, and use gene editing to create disease models and develop therapeutics that were not previously possible.
Harnessing a natural system to precisely edit the DNA of living things
The ability to precisely edit the genome of a living cell holds enormous potential for accelerating life science research and biotechnology and even treating human disease. At the Broad Institute, researchers are pioneering the development and sharing of tools, such as CRISPR-based editing and genome engineering systems. These tools enable scientists worldwide to probe the genetic underpinnings of biological systems; quickly create cell and animal models for research; design low-cost diagnostics; precisely and simply edit the DNA of living things, from plants to people; and perhaps one day develop a powerful therapeutic approach.