Sellar RS, Sperling AS, Słabicki M, et al. Degradation of GSPT1 causes TP53-independent cell death in leukemia whilst sparing normal hematopoietic stem cells. J Clin Invest. 2022. doi:10.1172/JCI153514.DOIGoogle ScholarPubMed
Publications
Nehme R, Pietilainen O, Artomov M, et al. The 22q11.2 region regulates presynaptic gene-products linked to schizophrenia. Nat Commun. 2022;13(1):3690. doi:10.1038/s41467-022-31436-8.DOIGoogle ScholarPubMed
Dou Q, Turanov AA, Mariotti M, et al. Selenoprotein TXNRD3 supports male fertility via the redox regulation of spermatogenesis. J Biol Chem. 2022:102183. doi:10.1016/j.jbc.2022.102183.DOIGoogle ScholarPubMed
Chaffin M, Papangeli I, Simonson B, et al. Single-nucleus profiling of human dilated and hypertrophic cardiomyopathy. Nature. 2022. doi:10.1038/s41586-022-04817-8.DOIGoogle ScholarPubMed
Anahtar M, Chan LW, Ko H, et al. Host protease activity classifies pneumonia etiology. Proc Natl Acad Sci U S A. 2022;119(25):e2121778119. doi:10.1073/pnas.2121778119.DOIGoogle ScholarPubMed
Sherman MA, Yaari AU, Priebe O, Dietlein F, Loh P-R, Berger B. Genome-wide mapping of somatic mutation rates uncovers drivers of cancer. Nat Biotechnol. 2022. doi:10.1038/s41587-022-01353-8.DOIGoogle ScholarPubMed
Bustoros M, Anand S, Sklavenitis-Pistofidis R, et al. Genetic subtypes of smoldering multiple myeloma are associated with distinct pathogenic phenotypes and clinical outcomes. Nat Commun. 2022;13(1):3449. doi:10.1038/s41467-022-30694-w.DOIGoogle ScholarPubMed
Jonsson H, Zhang F, Dunlap G, et al. Granzyme K CD8 T cells form a core population in inflamed human tissue. Sci Transl Med. 2022;14(649):eabo0686. doi:10.1126/scitranslmed.abo0686.DOIGoogle ScholarPubMed
Chen N, Golczer G, Ghose S, et al. YAP1 maintains active chromatin state in head and neck squamous cell carcinomas that promotes tumorigenesis through cooperation with BRD4. Cell Rep. 2022;39(11):110970. doi:10.1016/j.celrep.2022.110970.DOIGoogle ScholarPubMed
Hallacli E, Kayatekin C, Nazeen S, et al. The Parkinson's disease protein alpha-synuclein is a modulator of processing bodies and mRNA stability. Cell. 2022;185(12):2035-2056.e33. doi:10.1016/j.cell.2022.05.008.DOIGoogle ScholarPubMed