Home>News & Publications:Scientific Publications>Scientific Publications

Scientific Publications

Search by Keyword(s)
or use Advanced Search
Found 2255 results

Search Results

2014
ZFHX4 Interacts with the NuRD Core Member CHD4 and Regulates the Glioblastoma Tumor-Initiating Cell State.Chudnovsky, Y., Kim D., Zheng S., Whyte WA, Bansal M., Bray MA, Gopal S., Theisen MA, Bilodeau S., Thiru P., Muffat J., Yilmaz OH, Mitalipova M., Woolard K., Lee J., Nishimura R., Sakata N., Fine HA, Carpenter AE, Silver SJ, et al. Cell reports, 2014/01/15, (2014) Read More / View Supplemental Materials
Abstract
Autophagy is essential for cardiac morphogenesis during vertebrate development.Lee, E., Koo Y., Ng A., Wei Y., Luby-Phelps K., Juraszek A., Xavier RJ, Cleaver O., Levine B., and Amatruda JF Autophagy, 2014/01/14, Volume 10, Issue 4, (2014) Read More / View Supplemental Materials
Abstract
Differential Effect of Genetic Burden on Disease Phenotypes in Crohn's Disease and Ulcerative Colitis: Analysis of a North American Cohort.Ananthakrishnan, AN, Huang H., Nguyen DD, Sauk J., Yajnik V., and Xavier RJ The American journal of gastroenterology, 2014/01/14, (2014) Read More / View Supplemental Materials
Abstract
Harnessing evolutionary fitness in Plasmodium falciparum for drug discovery and suppressing resistance.Lukens, AK, Ross LS, Heidebrecht R., Javier Gamo F., Lafuente-Monasterio MJ, Booker ML, Hartl DL, Wiegand RC, and Wirth DF Proceedings of the National Academy of Sciences of the United States of America, 2014/01/14, Volume 111, Issue 2, p.799-804, (2014) Read More / View Supplemental Materials
Abstract
De novo fatty acid synthesis at the mitotic exit is required to complete cellular division.Scaglia, N., Tyekucheva S., Zadra G., Photopoulos C., and Loda M. Cell cycle (Georgetown, Tex.), 2014/01/13, Volume 13, Issue 5, (2014) Read More / View Supplemental Materials
Abstract
Using transcription of six Puccinia triticina races to identify the effective secretome during infection of wheat.Bruce, M., Neugebauer KA, Joly DL, Migeon P., Cuomo CA, Wang S., Akhunov E., Bakkeren G., Kolmer JA, and Fellers JP Frontiers in plant science, 2014/01/13, Volume 4, p.520, (2014) Read More / View Supplemental Materials
Abstract
Widespread genetic heterogeneity in multiple myeloma: implications for targeted therapy.Lohr, JG, Stojanov P., Carter SL, Cruz-Gordillo P., Lawrence MS, Auclair D., Sougnez C., Knoechel B., Gould J., Saksena G., Cibulskis K., McKenna A., Chapman MA, Straussman R., Levy J., Perkins LM, Keats JJ, Schumacher SE, Rosenberg M., Multiple Myeloma Research Consortium, et al. Cancer cell, 2014/01/13, Volume 25, Issue 1, p.91-101, (2014) Read More / View Supplemental Materials
Abstract
Common Variation in Fatty Acid Metabolic Genes and Risk of Incident Sudden Cardiac Arrest.Lemaitre, RN, Johnson CO, Hesselson S., Sotoodhenia N., McKnight B., Sitlani CM, Rea TD, King IB, Kwok PY, Mak A., Li G., Brody J., Larson E., Mozaffarian D., Psaty BM, Huertas-Vazquez A., Tardif JC, Albert CM, Lyytikäinen LP, Arking DE, et al. Heart rhythm : the official journal of the Heart Rhythm Society, 2014/01/10, (2014) Read More / View Supplemental Materials
Abstract
β-Aminoisobutyric acid induces browning of white fat and hepatic β-oxidation and is inversely correlated with cardiometabolic risk factors.Roberts, LD, Boström P., O'Sullivan JF, Schinzel RT, Lewis GD, Dejam A., Lee YK, Palma MJ, Calhoun S., Georgiadi A., Chen MH, Ramachandran VS, Larson MG, Bouchard C., Rankinen T., Souza AL, Clish CB, Wang TJ, Estall JL, Soukas AA, et al. Cell metabolism, 2014/01/07, Volume 19, Issue 1, p.96-108, (2014) Read More / View Supplemental Materials
Abstract
Discovery and saturation analysis of cancer genes across 21 tumour types.Lawrence, MS, Stojanov P., Mermel CH, Robinson JT, Garraway LA, Golub T. R., Meyerson M., Gabriel SB, Lander E. S., and Getz G. Nature, 2014/01/05, (2014) Read More / View Supplemental Materials
Abstract
Genome-scale CRISPR-Cas9 knockout screening in human cells.Shalem, O., Sanjana NE, Hartenian E., Shi X., Scott DA, Mikkelsen TS, Heckl D., Ebert BL, Root DE, Doench JG, and Zhang F. Science (New York, N.Y.), 2014/01/03, Volume 343, Issue 6166, p.84-7, (2014) Read More / View Supplemental Materials
Abstract
The complete genome sequence of a Neanderthal from the Altai Mountains.Prüfer, K., Racimo F., Patterson N., Jay F., Sankararaman S., Sawyer S., Heinze A., Renaud G., Sudmant PH, de Filippo C., Li H., Mallick S., Dannemann M., Fu Q., Kircher M., Kuhlwilm M., Lachmann M., Meyer M., Ongyerth M., Siebauer M., et al. Nature, 2014/01/02, Volume 505, Issue 7481, p.43-9, (2014) Read More / View Supplemental Materials
Abstract
The influence of polygenic risk scores on heritability of anti-CCP level in RA.Cui, J., Taylor KE, Lee YC, Källberg H., Weinblatt ME, Coblyn JS, Klareskog L., Criswell LA, Gregersen PK, Shadick NA, Plenge RM, and Karlson EW Genes and immunity, 2014/01/02, (2014) Read More / View Supplemental Materials
Abstract
Mutations in CSPP1 Lead to Classical Joubert Syndrome.Akizu, N., Silhavy JL, Rosti RO, Scott E., Fenstermaker AG, Schroth J., Zaki MS, Sanchez H., Gupta N., Kabra M., Kara M., Ben-Omran T., Rosti B., Guemez-Gamboa A., Spencer E., Pan R., Cai N., Abdellateef M., Gabriel S., Halbritter J., et al. American journal of human genetics, 2014/01/02, Volume 94, Issue 1, p.80-6, (2014) Read More / View Supplemental Materials
Abstract
Probiotic microbes sustain youthful serum testosterone levels and testicular size in aging mice.Poutahidis, T., Springer A., Levkovich T., Qi P., Varian BJ, Lakritz JR, Ibrahim YM, Chatzigiagkos A., Alm EJ, and Erdman SE PloS one, 2014/01/02, Volume 9, Issue 1, p.e84877, (2014) Read More / View Supplemental Materials
Abstract
16S rRNA Gene Survey of Microbial Communities in Winogradsky Columns.Rundell, EA, Banta LM, Ward DV, Watts CD, Birren B., and Esteban DJ PloS one, 2014/01/01, Volume 9, Issue 8, p.e104134, (2014) Read More / View Supplemental Materials
Abstract
An Adjustable Gas-Mixing Device to Increase Feasibility of In Vitro Culture of Plasmodium falciparum Parasites in the Field.Bei, AK, Patel SD, Volkman SK, Ahouidi AD, Ndiaye D., Mboup S., and Wirth DF PloS one, 2014/01/01, Volume 9, Issue 3, p.e90928, (2014) Read More / View Supplemental Materials
Abstract
Allele-specific methylation occurs at genetic variants associated with complex disease.Hutchinson, JN, Raj T., Fagerness J., Stahl E., Viloria FT, Gimelbrant A., Seddon J., Daly M., Chess A., and Plenge R. PloS one, 2014/01/01, Volume 9, Issue 6, p.e98464, (2014) Read More / View Supplemental Materials
Abstract
Analysis of gene-gene interactions among common variants in coronary artery disease.Musameh, M., Wang W., Nelson C., Lluís-Ganella C., Subirana I., Elosua R., Hall A., Kathiresan S., Samani N., and Tomaszewski M. Heart, lung & circulation, 2014/01/01, Volume 23 Suppl 2, p.e19, (2014) Read More / View Supplemental Materials
Analysis of the Effects of Five Factors Relevant to In Vitro Chondrogenesis of Human Mesenchymal Stem Cells Using Factorial Design and High Throughput mRNA-Profiling.Jakobsen, RB, Ostrup E., Zhang X., Mikkelsen TS, and Brinchmann JE PloS one, 2014/01/01, Volume 9, Issue 5, p.e96615, (2014) Read More / View Supplemental Materials
Abstract
CELLCOUNTER: Novel Open-Source Software for Counting Cell Migration and Invasion In Vitro.Li, X., Yang H., Huang H., and Zhu T. BioMed research international, 2014/01/01, Volume 2014, p.863564, (2014) Read More / View Supplemental Materials
Abstract
Comorbidity of Severe Psychotic Disorders With Measures of Substance Use.Hartz, SM, Pato CN, Medeiros H., Cavazos-Rehg P., Sobell JL, Knowles JA, Bierut LJ, Pato MT, for the Genomic Psychiatry Cohort Consortium, Abbott C., Azevedo MH, Belliveau R., Bevilacqua E., Bromet EJ, Buckley PF, Dewan MJ, Escamilla MA, Fanous AH, Fochtmann LJ, Kinkead R., et al. JAMA psychiatry, 2014/01/01, (2014) Read More / View Supplemental Materials
Abstract
Comparative genomics of Australian isolates of the wheat stem rust pathogen Puccinia graminis f. sp. tritici reveals extensive polymorphism in candidate effector genes.Upadhyaya, NM, Garnica DP, Karaoglu H., Sperschneider J., Nemri A., Xu B., Mago R., Cuomo CA, Rathjen JP, Park RF, Ellis JG, and Dodds PN Frontiers in plant science, 2014/01/01, Volume 5, p.759, (2014) Read More / View Supplemental Materials
Abstract
Comparison of illumina and 454 deep sequencing in participants failing raltegravir-based antiretroviral therapy.Li, JZ, Chapman B., Charlebois P., Hofmann O., Weiner B., Porter AJ, Samuel R., Vardhanabhuti S., Zheng L., Eron J., Taiwo B., Zody MC, Henn MR, Kuritzkes DR, Hide W., ACTG A5262 Study Team, Wilson CC, Berzins BI, Acosta EP, Bastow B., et al. PloS one, 2014/01/01, Volume 9, Issue 3, p.e90485, (2014) Read More / View Supplemental Materials
Abstract
Complex host genetics influence the microbiome in inflammatory bowel disease.Knights, D., Silverberg MS, Weersma RK, Gevers D., Dijkstra G., Huang H., Tyler AD, van Sommeren S., Imhann F., Stempak JM, Huang H., Vangay P., Al-Ghalith GA, Russell C., Sauk J., Knight J., Daly M. J., Huttenhower C., and Xavier RJ Genome medicine, 2014/01/01, Volume 6, Issue 12, p.107, (2014) Read More / View Supplemental Materials
Abstract
Comprehensive functional annotation of 77 prostate cancer risk Loci.Hazelett, DJ, Rhie SK, Gaddis M., Yan C., Lakeland DL, Coetzee SG, consortium Ellipse/GAME-ON, consortium Practical, Henderson BE, Noushmehr H., Cozen W., Kote-Jarai Z., Eeles RA, Easton DF, Haiman CA, Lu W., Farnham PJ, and Coetzee GA PLoS genetics, 2014/01/01, Volume 10, Issue 1, p.e1004102, (2014) Read More / View Supplemental Materials
Abstract
Construction and application of a korean reference panel for imputing classical alleles and amino acids of human leukocyte antigen genes.Kim, K., Bang SY, Lee HS, and Bae SC PloS one, 2014/01/01, Volume 9, Issue 11, p.e112546, (2014) Read More / View Supplemental Materials
Abstract
CRISPRseek: A Bioconductor Package to Identify Target-Specific Guide RNAs for CRISPR-Cas9 Genome-Editing Systems.Zhu, LJ, Holmes BR, Aronin N., and Brodsky MH PloS one, 2014/01/01, Volume 9, Issue 9, p.e108424, (2014) Read More / View Supplemental Materials
Abstract
Cytoscape: the network visualization tool for GenomeSpace workflows.Demchak, B., Hull T., Reich M., Liefeld T., Smoot M., Ideker T., and Mesirov J. P. F1000Research, 2014/01/01, Volume 3, p.151, (2014) Read More / View Supplemental Materials
Abstract
A Description of the Molecular Signatures Database (MSigDB) Web Site.Liberzon, A. Methods in molecular biology (Clifton, N.J.), 2014/01/01, Volume 1150, p.153-60, (2014) Read More / View Supplemental Materials
Abstract
Dopamine genetic risk score predicts depressive symptoms in healthy adults and adults with depression.Pearson-Fuhrhop, KM, Dunn EC, Mortero S., Devan WJ, Falcone GJ, Lee P., Holmes AJ, Hollinshead MO, Roffman JL, Smoller JW, Rosand J., and Cramer SC PloS one, 2014/01/01, Volume 9, Issue 5, p.e93772, (2014) Read More / View Supplemental Materials
Abstract
Efficient Mutagenesis by Cas9 Protein-Mediated Oligonucleotide Insertion and Large-Scale Assessment of Single-Guide RNAs.Gagnon, JA, Valen E., Thyme SB, Huang P., Ahkmetova L., Pauli A., Montague TG, Zimmerman S., Richter C., and Schier AF PloS one, 2014/01/01, Volume 9, Issue 5, p.e98186, (2014) Read More / View Supplemental Materials
Abstract
Evidence that duplications of 22q11.2 protect against schizophrenia.Rees, E., Kirov G., Sanders A., Walters JT, Chambert KD, Shi J., Szatkiewicz J., O'Dushlaine C., Richards AL, Green EK, Jones I., Davies G., Legge SE, Moran JL, Pato C., Pato M., Genovese G., Levinson D., Duan J., Moy W., et al. Molecular psychiatry, 2014/01/01, Volume 19, Issue 1, p.37-40, (2014) Read More / View Supplemental Materials
Abstract
Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease.Escott-Price, V., Bellenguez C., Wang LS, Choi SH, Harold D., Jones L., Holmans P., Gerrish A., Vedernikov A., Richards A., Destefano AL, Lambert JC, Ibrahim-Verbaas CA, Naj AC, Sims R., Jun G., Bis JC, Beecham GW, Grenier-Boley B., Russo G., et al. PloS one, 2014/01/01, Volume 9, Issue 6, p.e94661, (2014) Read More / View Supplemental Materials
Abstract
Genetics and epigenetics of gliomas.Suvà, ML Swiss medical weekly, 2014/01/01, Volume 144, p.w14018, (2014) Read More / View Supplemental Materials
Abstract
Genome editing using cas9 nickases.Trevino, AE, and Zhang F. Methods in enzymology, 2014/01/01, Volume 546, p.161-74, (2014) Read More / View Supplemental Materials
Abstract
Genome-wide association studies to advance our understanding of critical cell types and pathways in rheumatoid arthritis: recent findings and challenges.Diogo, D., Okada Y., and Plenge RM Current opinion in rheumatology, 2014/01/01, Volume 26, Issue 1, p.85-92, (2014) Read More / View Supplemental Materials
Abstract
A genomic and evolutionary approach reveals non-genetic drug resistance in malaria.Herman, JD, Rice DP, Ribacke U., Silterra J., Deik AA, Moss EL, Broadbent KM, Neafsey DE, Desai MM, Clish CB, Mazitschek R., and Wirth DF Genome biology, 2014/01/01, Volume 15, Issue 11, p.511, (2014) Read More / View Supplemental Materials
Abstract
Gut Microbiota and the Paradox of Cancer Immunotherapy.Poutahidis, T., Kleinewietfeld M., and Erdman SE Frontiers in immunology, 2014/01/01, Volume 5, p.157, (2014) Read More / View Supplemental Materials
Abstract
High content image analysis identifies novel regulators of synaptogenesis in a high-throughput RNAi screen of primary neurons.Nieland, TJ, Logan DJ, Saulnier J., Lam D., Johnson C., Root DE, Carpenter AE, and Sabatini BL PloS one, 2014/01/01, Volume 9, Issue 3, p.e91744, (2014) Read More / View Supplemental Materials
Abstract
High risk population isolate reveals low frequency variants predisposing to intracranial aneurysms.Kurki, MI, Gaál EI, Kettunen J., Lappalainen T., Menelaou A., Anttila V., van 't Hof FN, von Und Zu Fraunberg M., Helisalmi S., Hiltunen M., Lehto H., Laakso A., Kivisaari R., Koivisto T., Ronkainen A., Rinne J., Kiemeney LA, Vermeulen SH, Kaunisto MA, Eriksson JG, et al. PLoS genetics, 2014/01/01, Volume 10, Issue 1, p.e1004134, (2014) Read More / View Supplemental Materials
Abstract
Identification of ALK Gene Alterations in Urothelial Carcinoma.Bellmunt, J., Selvarajah S., Rodig S., Salido M., de Muga S., Costa I., Bellosillo B., Werner L., Mullane S., Fay AP, O'Brien R., Barretina J., Minoche AE, Signoretti S., Montagut C., Himmelbauer H., Berman DM, Kantoff P., Choueiri TK, and Rosenberg JE PloS one, 2014/01/01, Volume 9, Issue 8, p.e103325, (2014) Read More / View Supplemental Materials
Abstract
An Image-Based Genetic Assay Identifies Genes in T1D Susceptibility Loci Controlling Cellular Antiviral Immunity in Mouse.Liao, J., Jijon HB, Kim IR, Goel G., Doan A., Sokol H., Bauer H., Herrmann BG, Lassen KG, and Xavier RJ PloS one, 2014/01/01, Volume 9, Issue 9, p.e108777, (2014) Read More / View Supplemental Materials
Abstract
An improved canine genome and a comprehensive catalogue of coding genes and non-coding transcripts.Hoeppner, MP, Lundquist A., Pirun M., Meadows JR, Zamani N., Johnson J., Sundström G., Cook A., FitzGerald MG, Swofford R., Mauceli E., Moghadam BT, Greka A., Alföldi J., Abouelleil A., Aftuck L., Bessette D., Berlin A., Brown A., Gearin G., et al. PloS one, 2014/01/01, Volume 9, Issue 3, p.e91172, (2014) Read More / View Supplemental Materials
Abstract
Integration of Sequence Data from a Consanguineous Family with Genetic Data from an Outbred Population Identifies PLB1 as a Candidate Rheumatoid Arthritis Risk Gene.Okada, Y., Diogo D., Greenberg JD, Mouassess F., Achkar WA, Fulton RS, Denny JC, Gupta N., Mirel D., Gabriel S., Li G., Kremer JM, Pappas DA, Carroll RJ, Eyler AE, Trynka G., Stahl EA, Cui J., Saxena R., Coenen MJ, et al. PloS one, 2014/01/01, Volume 9, Issue 2, p.e87645, (2014) Read More / View Supplemental Materials
Abstract
Intestinal microbiota of preterm infants differ over time and between hospitals.Taft, DH, Ambalavanan N., Schibler KR, Yu Z., Newburg DS, Ward DV, and Morrow AL Microbiome, 2014/01/01, Volume 2, p.36, (2014) Read More / View Supplemental Materials
Abstract
Joint modeling and registration of cell populations in cohorts of high-dimensional flow cytometric data.Pyne, S., Lee SX, Wang K., Irish J., Tamayo P., Nazaire MD, Duong T., Ng SK, Hafler D., Levy R., Nolan GP, Mesirov J., and McLachlan GJ PloS one, 2014/01/01, Volume 9, Issue 7, p.e100334, (2014) Read More / View Supplemental Materials
Abstract
Lack of evidence for a role of islet autoimmunity in the aetiology of canine diabetes mellitus.Ahlgren, KM, Fall T., Landegren N., Grimelius L., von Euler H., Sundberg K., Lindblad-Toh K., Lobell A., Hedhammar A., Andersson G., Hansson-Hamlin H., Lernmark A., and Kämpe O. PloS one, 2014/01/01, Volume 9, Issue 8, p.e105473, (2014) Read More / View Supplemental Materials
Abstract
Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function.Tang, W., Kowgier M., Loth DW, Soler Artigas M., Joubert BR, Hodge E., Gharib SA, Smith AV, Ruczinski I., Gudnason V., Mathias RA, Harris TB, Hansel NN, Launer LJ, Barnes KC, Hansen JG, Albrecht E., Aldrich MC, Allerhand M., Barr RG, et al. PloS one, 2014/01/01, Volume 9, Issue 7, p.e100776, (2014) Read More / View Supplemental Materials
Abstract
Laser microdissection of the alveolar duct enables single-cell genomic analysis.Bennett, RD, Ysasi AB, Belle JM, Wagner WL, Konerding MA, Blainey PC, Pyne S., and Mentzer SJ Frontiers in oncology, 2014/01/01, Volume 4, p.260, (2014) Read More / View Supplemental Materials
Abstract
Long-range correlation properties in timing of skilled piano performance: the influence of auditory feedback and deep brain stimulation.Herrojo Ruiz, M., Hong SB, Hennig H., Altenmüller E., and Kühn AA Frontiers in psychology, 2014/01/01, Volume 5, p.1030, (2014) Read More / View Supplemental Materials
Abstract
Massively parallel sequencing of human urinary exosome/microvesicle RNA reveals a predominance of non-coding RNA.Miranda, KC, Bond DT, Levin JZ, Adiconis X., Sivachenko A., Russ C., Brown D., Nusbaum C., and Russo LM PloS one, 2014/01/01, Volume 9, Issue 5, p.e96094, (2014) Read More / View Supplemental Materials
Abstract
Meta-Analysis Identifies Gene-by-Environment Interactions as Demonstrated in a Study of 4,965 Mice.Kang, EY, Han B., Furlotte N., Joo JW, Shih D., Davis RC, Lusis AJ, and Eskin E. PLoS genetics, 2014/01/01, Volume 10, Issue 1, p.e1004022, (2014) Read More / View Supplemental Materials
Abstract
MOSAIK: A Hash-Based Algorithm for Accurate Next-Generation Sequencing Short-Read Mapping.Lee, WP, Stromberg MP, Ward A., Stewart C., Garrison EP, and Marth GT PloS one, 2014/01/01, Volume 9, Issue 3, p.e90581, (2014) Read More / View Supplemental Materials
Abstract
Mu-8: visualizing differences between proteins and their families.Mercer, JD, Pandian B., Lex A., Bonneel N., and Pfister H. BMC proceedings, 2014/01/01, Volume 8, Issue Suppl 2 Proceedings of the 3rd Annual Symposium on Biologica, p.S5, (2014) Read More / View Supplemental Materials
Abstract
New Approaches to Target T-ALL.Roti, G., and Stegmaier K. Frontiers in oncology, 2014/01/01, Volume 4, p.170, (2014) Read More / View Supplemental Materials
Abstract
OTX2 Duplication Is Implicated in Hemifacial Microsomia.Zielinski, D., Markus B., Sheikh M., Gymrek M., Chu C., Zaks M., Srinivasan B., Hoffman JD, Aizenbud D., and Erlich Y. PloS one, 2014/01/01, Volume 9, Issue 5, p.e96788, (2014) Read More / View Supplemental Materials
Abstract
A Pan-Cancer Analysis of Transcriptome Changes Associated with Somatic Mutations in U2AF1 Reveals Commonly Altered Splicing Events.Brooks, AN, Choi PS, de Waal L., Sharifnia T., Imielinski M., Saksena G., Pedamallu CS, Sivachenko A., Rosenberg M., Chmielecki J., Lawrence MS, Deluca DS, Getz G., and Meyerson M. PloS one, 2014/01/01, Volume 9, Issue 1, p.e87361, (2014) Read More / View Supplemental Materials
Abstract
Pathway analyses implicate glial cells in schizophrenia.Duncan, LE, Holmans PA, Lee PH, O'Dushlaine CT, Kirby AW, Smoller JW, Öngür D., and Cohen BM PloS one, 2014/01/01, Volume 9, Issue 2, p.e89441, (2014) Read More / View Supplemental Materials
Abstract
Personal neoantigen cancer vaccines: The momentum builds.Fritsch, EF, Hacohen N., and Wu CJ Oncoimmunology, 2014/01/01, Volume 3, p.e29311, (2014) Read More / View Supplemental Materials
Abstract
Pilon: an integrated tool for comprehensive microbial variant detection and genome assembly improvement.Walker, BJ, Abeel T., Shea T., Priest M., Abouelliel A., Sakthikumar S., Cuomo CA, Zeng Q., Wortman J., Young SK, and Earl AM PloS one, 2014/01/01, Volume 9, Issue 11, p.e112963, (2014) Read More / View Supplemental Materials
Abstract
Plasmodium falciparum gene expression measured directly from tissue during human infection.Van Tyne, D., Tan Y., Daily JP, Kamiza S., Seydel K., Taylor T., Mesirov J. P., Wirth DF, and Milner DA Jr Genome medicine, 2014/01/01, Volume 6, Issue 11, p.110, (2014) Read More / View Supplemental Materials
Abstract
Quantitative-proteomic comparison of alpha and Beta cells to uncover novel targets for lineage reprogramming.Choudhary, A., Hu He K., Mertins P., Udeshi ND, Dančík V., Fomina-Yadlin D., Kubicek S., Clemons PA, Schreiber SL, Carr SA, and Wagner BK PloS one, 2014/01/01, Volume 9, Issue 4, p.e95194, (2014) Read More / View Supplemental Materials
Abstract
Rare deleterious mutations of the gene EFR3A in autism spectrum disorders.Gupta, AR, Pirruccello M., Cheng F., Kang HJ, Fernandez TV, Baskin JM, Choi M., Liu L., Ercan-Sencicek AG, Murdoch JD, Klei L., Neale BM, Franjic D., Daly M. J., Lifton RP, De Camilli P., Zhao H., Sestan N., and State MW Molecular autism, 2014/01/01, Volume 5, p.31, (2014) Read More / View Supplemental Materials
Abstract
Re-sequencing Expands Our Understanding of the Phenotypic Impact of Variants at GWAS Loci.Service, SK, Teslovich TM, Fuchsberger C., Ramensky V., Yajnik P., Koboldt DC, Larson DE, Zhang Q., Lin L., Welch R., Ding L., McLellan MD, O'Laughlin M., Fronick C., Fulton LL, Magrini V., Swift A., Elliott P., Jarvelin MR, Kaakinen M., et al. PLoS genetics, 2014/01/01, Volume 10, Issue 1, p.e1004147, (2014) Read More / View Supplemental Materials
Abstract
Revitalizing psychiatric therapeutics.Hyman, SE Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2014/01/01, Volume 39, Issue 1, p.220-9, (2014) Read More / View Supplemental Materials
Abstract
RNA-Guided Genome Editing of Mammalian Cells.Pyzocha, NK, Ran FA, Hsu PD, and Zhang F. Methods in molecular biology (Clifton, N.J.), 2014/01/01, Volume 1114, p.269-77, (2014) Read More / View Supplemental Materials
Abstract
Rs964184 (APOA5-A4-C3-A1) Is Related to Elevated Plasma Triglyceride Levels, but Not to an Increased Risk for Vascular Events in Patients with Clinically Manifest Vascular Disease.van de Woestijne, AP, van der Graaf Y., de Bakker PI, Asselbergs FW, Spiering W., Visseren FL, and SMART Study Group PloS one, 2014/01/01, Volume 9, Issue 6, p.e101082, (2014) Read More / View Supplemental Materials
Abstract
Selective HDAC inhibition for the disruption of latent HIV-1 infection.Barton, KM, Archin NM, Keedy KS, Espeseth AS, Zhang YL, Gale J., Wagner FF, Holson EB, and Margolis DM PloS one, 2014/01/01, Volume 9, Issue 8, p.e102684, (2014) Read More / View Supplemental Materials
Abstract
A Simple Repeat Polymorphism in the MITF-M Promoter Is a Key Regulator of White Spotting in Dogs.Baranowska Körberg, I., Sundström E., Meadows JR, Rosengren Pielberg G., Gustafson U., Hedhammar A., Karlsson EK, Seddon J., Söderberg A., Vilà C., Zhang X., Akesson M., Lindblad-Toh K., Andersson G., and Andersson L. PloS one, 2014/01/01, Volume 9, Issue 8, p.e104363, (2014) Read More / View Supplemental Materials
Abstract
Src Mutation Induces Acquired Lapatinib Resistance in ERBB2-Amplified Human Gastroesophageal Adenocarcinoma Models.Hong, YS, Kim J., Pectasides E., Fox C., Hong SW, Ma Q., Wong GS, Peng S., Stachler MD, Thorner AR, Van Hummelen P., and Bass AJ PloS one, 2014/01/01, Volume 9, Issue 10, p.e109440, (2014) Read More / View Supplemental Materials
Abstract
Standardized metadata for human pathogen/vector genomic sequences.Dugan, VG, Emrich SJ, Giraldo-Calderón GI, Harb OS, Newman RM, Pickett BE, Schriml LM, Stockwell TB, Stoeckert CJ Jr, Sullivan DE, Singh I., Ward DV, Yao A., Zheng J., Barrett T., Birren B., Brinkac L., Bruno VM, Caler E., Chapman S., et al. PloS one, 2014/01/01, Volume 9, Issue 6, p.e99979, (2014) Read More / View Supplemental Materials
Abstract
Understanding the sequence requirements of protein families: insights from the BioVis 2013 contests.Ray, WC, Rumpf RW, Sullivan B., Callahan N., Magliery T., Machiraju R., Wong B., Krzywinski M., and Bartlett CW BMC proceedings, 2014/01/01, Volume 8, Issue Suppl 2 Proceedings of the 3rd Annual Symposium on Biologica, p.S1, (2014) Read More / View Supplemental Materials
Abstract
YMAP: a pipeline for visualization of copy number variation and loss of heterozygosity in eukaryotic pathogens.Abbey, DA, Funt J., Lurie-Weinberger MN, Thompson DA, Regev A., Myers CL, and Berman J. Genome medicine, 2014/01/01, Volume 6, Issue 11, p.100, (2014) Read More / View Supplemental Materials
Abstract
ZBED6 Modulates the Transcription of Myogenic Genes in Mouse Myoblast Cells.Jiang, L., Wallerman O., Younis S., Rubin CJ, Gilbert ER, Sundström E., Ghazal A., Zhang X., Wang L., Mikkelsen TS, Andersson G., and Andersson L. PloS one, 2014/01/01, Volume 9, Issue 4, p.e94187, (2014) Read More / View Supplemental Materials
Abstract
Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defenseKG, Lassen, P Kuballa, KL Conway, KK Patel, CE Becker, JM Peloquin, EJ Villablanca, JM Norman, T Liu, RJ Heath, ML Becker, L Fagbami, H Horn, J Mercer, OH Yilmaz, JJ Jaffe, AF Shamji, AK Bhan, SA Carr, MJ Daly, et al. Molecular & cellular proteomics : MCP, (2014) Read More / View Supplemental Materials
2013
S-Nitrosothiol Signaling Regulates Liver Development and Improves Outcome following Toxic Liver Injury.Cox, AG, Saunders DC, Kelsey PB Jr, Conway AA, Tesmenitsky Y., Marchini JF, Brown KK, Stamler JS, Colagiovanni DB, Rosenthal GJ, Croce KJ, North TE, and Goessling W. Cell reports, 2013/12/31, (2013) Read More / View Supplemental Materials
Abstract
Pilot investigation of isradipine in the treatment of bipolar depression motivated by genome-wide association.Ostacher, MJ, Iosifescu DV, Hay A., Blumenthal SR, Sklar P., and Perlis RH Bipolar disorders, 2013/12/27, (2013) Read More / View Supplemental Materials
Abstract
Genetics of rheumatoid arthritis contributes to biology and drug discovery.Okada, Y., Wu D., Trynka G., Raj T., Terao C., Ikari K., Kochi Y., Ohmura K., Suzuki A., Yoshida S., Graham RR, Manoharan A., Ortmann W., Bhangale T., Denny JC, Carroll RJ, Eyler AE, Greenberg JD, Kremer JM, Pappas DA, et al. Nature, 2013/12/25, (2013) Read More / View Supplemental Materials
Abstract
Landscape of genomic alterations in cervical carcinomas.Ojesina, AI, Lichtenstein L., Freeman SS, Pedamallu CS, Imaz-Rosshandler I., Pugh TJ, Cherniack AD, Ambrogio L., Cibulskis K., Bertelsen B., Romero-Cordoba S., Treviño V., Vazquez-Santillan K., Guadarrama AS, Wright AA, Rosenberg MW, Duke F., Kaplan B., Wang R., Nickerson E., et al. Nature, 2013/12/25, (2013) Read More / View Supplemental Materials
Abstract
Successful whole-exome sequencing from a prostate cancer bone metastasis biopsy.Van Allen, EM, Foye A., Wagle N., Kim W., Carter SL, McKenna A., Simko JP, Garraway LA, and Febbo PG Prostate cancer and prostatic diseases, 2013/12/24, (2013) Read More / View Supplemental Materials
Abstract
Bacterial toxins and small molecules elucidate endosomal trafficking.Slater, LH, Clatworthy AE, and Hung DT Trends in microbiology, 2013/12/23, (2013) Read More / View Supplemental Materials
Abstract
TRAF2 is an NF-κB-activating oncogene in epithelial cancers.Shen, RR, Zhou AY, Kim E., O'Connell JT, Hagerstrand D., Beroukhim R., and Hahn WC Oncogene, 2013/12/23, (2013) Read More / View Supplemental Materials
Abstract
Adult neural stem cells in distinct microdomains generate previously unknown interneuron types.Merkle, FT, Fuentealba LC, Sanders TA, Magno L., Kessaris N., and Alvarez-Buylla A. Nature neuroscience, 2013/12/22, (2013) Read More / View Supplemental Materials
Abstract
Genomic insights into WNT/β-catenin signaling.Rosenbluh, J., Wang X., and Hahn WC Trends in pharmacological sciences, 2013/12/20, (2013) Read More / View Supplemental Materials
Abstract
Aspirin Use, 8q24 Single Nucleotide Polymorphism rs6983267, and Colorectal Cancer According to CTNNB1 Alterations.Nan, H., Morikawa T., Suuriniemi M., Imamura Y., Werner L., Kuchiba A., Yamauchi M., Hunter DJ, Kraft P., Giovannucci EL, Fuchs CS, Ogino S., Freedman ML, and Chan AT Journal of the National Cancer Institute, 2013/12/18, Volume 105, Issue 24, p.1852-61, (2013) Read More / View Supplemental Materials
Abstract
Genome-wide probing of RNA structure reveals active unfolding of mRNA structures in vivo.Rouskin, S., Zubradt M., Washietl S., Kellis M., and Weissman JS Nature, 2013/12/15, (2013) Read More / View Supplemental Materials
Abstract
Meta-analysis of gene-level tests for rare variant association.Liu, DJ, Peloso GM, Zhan X., Holmen OL, Zawistowski M., Feng S., Nikpay M., Auer PL, Goel A., Zhang H., Peters U., Farrall M., Orho-Melander M., Kooperberg C., McPherson R., Watkins H., Willer CJ, Hveem K., Melander O., Kathiresan S., et al. Nature genetics, 2013/12/15, (2013) Read More / View Supplemental Materials
Abstract
Reduced local mutation density in regulatory DNA of cancer genomes is linked to DNA repair.Polak, P., Lawrence MS, Haugen E., Stoletzki N., Stojanov P., Thurman RE, Garraway LA, Mirkin S., Getz G., Stamatoyannopoulos JA, and Sunyaev SR Nature biotechnology, 2013/12/15, (2013) Read More / View Supplemental Materials
Abstract
Sterilization of granulomas is common in active and latent tuberculosis despite within-host variability in bacterial killing.Lin, PL, Ford CB, Coleman MT, Myers AJ, Gawande R., Ioerger T., Sacchettini J., Fortune SM, and Flynn JL Nature medicine, 2013/12/15, (2013) Read More / View Supplemental Materials
Abstract
EMRE is an essential component of the mitochondrial calcium uniporter complex.Sancak, Y., Markhard AL, Kitami T., Kovács-Bogdán E., Kamer KJ, Udeshi ND, Carr SA, Chaudhuri D., Clapham DE, Li AA, Calvo SE, Goldberger O., and Mootha VK Science (New York, N.Y.), 2013/12/13, Volume 342, Issue 6164, p.1379-82, (2013) Read More / View Supplemental Materials
Abstract
Resource competition may lead to effective treatment of antibiotic resistant infections.Gomes, AL, Galagan JE, and Segrè D. PloS one, 2013/12/13, Volume 8, Issue 12, p.e80775, (2013) Read More / View Supplemental Materials
Abstract
Systematic discovery and characterization of regulatory motifs in ENCODE TF binding experiments.Kheradpour, P., and Kellis M. Nucleic acids research, 2013/12/13, (2013) Read More / View Supplemental Materials
Abstract
Genome-wide analyses implicate 33 loci in heritable dog osteosarcoma, including regulatory variants near CDKN2A/B.Karlsson, EK, Sigurdsson S., Ivansson E., Thomas R., Elvers I., Wright J., Howald C., Tonomura N., Perloski M., Swofford R., Biagi T., Fryc S., Anderson N., Courtay-Cahen C., Youell L., Ricketts SL, Mandlebaum S., Rivera P., von Euler H., Kisseberth WC, et al. Genome biology, 2013/12/12, Volume 14, Issue 12, p.R132, (2013) Read More / View Supplemental Materials
Abstract
High-throughput genetic screen for synaptogenic factors: identification of LRP6 as critical for excitatory synapse development.Sharma, K., Choi SY, Zhang Y., Nieland TJ, Long S., Li M., and Huganir RL Cell reports, 2013/12/12, Volume 5, Issue 5, p.1330-41, (2013) Read More / View Supplemental Materials
Abstract
Discovery and characterization of super-enhancer-associated dependencies in diffuse large B cell lymphoma.Chapuy, B., McKeown MR, Lin CY, Monti S., Roemer MG, Qi J., Rahl PB, Sun HH, Yeda KT, Doench JG, Reichert E., Kung AL, Rodig SJ, Young RA, Shipp M. A., and Bradner JE Cancer cell, 2013/12/09, Volume 24, Issue 6, p.777-90, (2013) Read More / View Supplemental Materials
Abstract
Integrative and Comparative Genomic Analysis of Lung Squamous Cell Carcinomas in East Asian Patients.Kim, Y., Hammerman PS, Kim J., Yoon JA, Lee Y., Sun JM, Wilkerson MD, Pedamallu CS, Cibulskis K., Yoo YK, Lawrence MS, Stojanov P., Carter SL, McKenna A., Stewart C., Sivachenko AY, Oh IJ, Kim HK, Choi YS, Kim K., et al. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013/12/09, (2013) Read More / View Supplemental Materials
Abstract
SQSTM1 Is a Pathogenic Target of 5q Copy Number Gains in Kidney Cancer.Li, L., Shen C., Nakamura E., Ando K., Signoretti S., Beroukhim R., Cowley GS, Lizotte P., Liberzon E., Bair S., Root DE, Tamayo P., Tsherniak A., Cheng SC, Tabak B., Jacobsen A., Hakimi AA, Schultz N., Ciriello G., Sander C., et al. Cancer cell, 2013/12/09, Volume 24, Issue 6, p.738-50, (2013) Read More / View Supplemental Materials
Abstract
Meclizine inhibits mitochondrial respiration through direct targeting of cytosolic phosphoethanolamine metabolism.Gohil, VM, Zhu L., Baker CD, Cracan V., Yaseen A., Jain M., Clish CB, Brookes PS, Bakovic M., and Mootha VK The Journal of biological chemistry, 2013/12/06, Volume 288, Issue 49, p.35387-95, (2013) Read More / View Supplemental Materials
Abstract
Statistical design for biospecimen cohort size in proteomics-based biomarker discovery and verification studies.Skates, SJ, Gillette MA, LaBaer J., Carr SA, Anderson L., Liebler DC, Ransohoff D., Rifai N., Kondratovich M., Težak Ž., Mansfield E., Oberg AL, Wright I., Barnes G., Gail M., Mesri M., Kinsinger CR, Rodriguez H., and Boja ES Journal of proteome research, 2013/12/06, Volume 12, Issue 12, p.5383-94, (2013) Read More / View Supplemental Materials
Abstract