Publications

Unfinished business in chronic lymphocytic leukemia: translational and clinical priorities for a cure.

Wu CJ, Caligaris-Cappio F, Chiorazzi N, et al. Unfinished business in chronic lymphocytic leukemia: translational and clinical priorities for a cure. Blood. 2026;148(2):175-186. doi:10.1182/blood.2025032393PubMed DOI Google Scholar

TGF-β coordinates alanine synthesis and import for myofibroblast differentiation in pulmonary fibrosis.

Li F, Vigder N, Ziehr DR, et al. TGF-β coordinates alanine synthesis and import for myofibroblast differentiation in pulmonary fibrosis. JCI insight. 2026;11(13). doi:10.1172/jci.insight.199449PubMed DOI Google Scholar

Inactivation of CDKN2AARF Promotes p53-Independent Remodeling of the PDAC Tumor Microenvironment.

Ferreira S, Flowers BM, Choi WY, et al. Inactivation of CDKN2AARF Promotes p53-Independent Remodeling of the PDAC Tumor Microenvironment. Cancer research. 2026;86(13):3109-3122. doi:10.1158/0008-5472.CAN-25-1969PubMed DOI PubMed Central Google Scholar

PMCID

PMC13290023

Inhibition of USP7 Destabilizes the Noncanonical PRC1.1 Complex and Induces Neuroblastoma Differentiation.

Cmarik EA, Wahi A, Chandekar SS, et al. Inhibition of USP7 Destabilizes the Noncanonical PRC1.1 Complex and Induces Neuroblastoma Differentiation. Molecular cancer research : MCR. 2026;24(7):555-575. doi:10.1158/1541-7786.MCR-25-1153PubMed DOI PubMed Central Google Scholar

PMCID

PMC13082235

Combining menin and MEK inhibition to target poor prognosis KMT2A-rearranged RAS pathway-mutant acute myeloid leukemia.

Scheidegger N, Schneider C, Alexe G, et al. Combining menin and MEK inhibition to target poor prognosis KMT2A-rearranged RAS pathway-mutant acute myeloid leukemia. Blood advances. 2026;10(13):4757-4771. doi:10.1182/bloodadvances.2025016208PubMed DOI Google Scholar

Peptide-MHC-targeted engineered virus-like particles enable selective priming and gene editing of tumor-specific T cells.

Shim BH, Zhao H, Queenan JA, Smith BE, Birnbaum ME, Liu DR. Peptide-MHC-targeted engineered virus-like particles enable selective priming and gene editing of tumor-specific T cells. Cell reports. 2026;45(6):117510. doi:10.1016/j.celrep.2026.117510PubMed DOI Google Scholar

Accurate trajectory inference in time-series spatial transcriptomics with structurally-constrained optimal transport.

Bryan JP, Farhi SL, Cleary B. Accurate trajectory inference in time-series spatial transcriptomics with structurally-constrained optimal transport. Nature communications. 2026. doi:10.1038/s41467-026-74927-8PubMed DOI Google Scholar

Genome-wide absolute quantification of chromatin looping.

Jusuf JM, Yang JH, Toppen J, et al. Genome-wide absolute quantification of chromatin looping. Nature structural & molecular biology. 2026. doi:10.1038/s41594-026-01819-2PubMed DOI Google Scholar

Experiment-guided AlphaFold3 resolves measurement-consistent protein ensembles.

Maddipatla A, Bojan NS, Bojan M, et al. Experiment-guided AlphaFold3 resolves measurement-consistent protein ensembles. Nature biotechnology. 2026. doi:10.1038/s41587-026-03166-5PubMed DOI Google Scholar

An integrated cell atlas of 2.4 million cardiac cells across 209 individuals in health and disease.

Datar Y, Chaffin M, Simonson B, Mandia A, Ellinor PT. An integrated cell atlas of 2.4 million cardiac cells across 209 individuals in health and disease. Nature cardiovascular research. 2026. doi:10.1038/s44161-026-00831-5PubMed DOI Google Scholar