Kummerlowe C, Mwakamui S, Hughes TK, et al. Single-cell profiling of environmental enteropathy reveals signatures of epithelial remodeling and immune activation. Sci Transl Med. 2022;14(660):eabi8633. doi:10.1126/scitranslmed.abi8633.DOIGoogle ScholarPubMed
Publications
Roh W, Geffen Y, Cha H, et al. High-resolution profiling of lung adenocarcinoma identifies expression subtypes with specific biomarkers and clinically relevant vulnerabilities. Cancer Res. 2022. doi:10.1158/0008-5472.CAN-22-0432.DOIGoogle ScholarPubMed
Sazonovs A, Stevens CR, Venkataraman GR, et al. Large-scale sequencing identifies multiple genes and rare variants associated with Crohn's disease susceptibility. Nat Genet. 2022. doi:10.1038/s41588-022-01156-2.DOIGoogle ScholarPubMed
Tye MA, Payne C, Johansson C, et al. Elucidating the path to Plasmodium prolyl-tRNA synthetase inhibitors that overcome halofuginone resistance. Nat Commun. 2022;13(1):4976. doi:10.1038/s41467-022-32630-4.DOIGoogle ScholarPubMed
Fu JM, Satterstrom K, Peng M, et al. Rare coding variation provides insight into the genetic architecture and phenotypic context of autism. Nat Genet. 2022. doi:10.1038/s41588-022-01104-0.DOIGoogle ScholarPubMed
Sanidas I, Lee H, Rumde PH, et al. Chromatin-bound RB targets promoters, enhancers, and CTCF-bound loci and is redistributed by cell-cycle progression. Mol Cell. 2022. doi:10.1016/j.molcel.2022.07.014.DOIGoogle ScholarPubMed
Wong F, Stokes JM, Bening SC, Vidoudez C, Trauger SA, Collins JJ. Reactive metabolic byproducts contribute to antibiotic lethality under anaerobic conditions. Mol Cell. 2022. doi:10.1016/j.molcel.2022.07.009.DOIGoogle ScholarPubMed
Stogsdill JA, Kim K, Binan L, Farhi SL, Levin JZ, Arlotta P. Pyramidal neuron subtype diversity governs microglia states in the neocortex. Nature. 2022. doi:10.1038/s41586-022-05056-7.DOIGoogle ScholarPubMed
Najjar D, Rainbow J, Timilsina SS, et al. A lab-on-a-chip for the concurrent electrochemical detection of SARS-CoV-2 RNA and anti-SARS-CoV-2 antibodies in saliva and plasma. Nat Biomed Eng. 2022. doi:10.1038/s41551-022-00919-w.DOIGoogle ScholarPubMed
Chen RJ, Lu MY, Williamson DFK, et al. Pan-cancer integrative histology-genomic analysis via multimodal deep learning. Cancer Cell. 2022;40(8):865-878.e6. doi:10.1016/j.ccell.2022.07.004.DOIGoogle ScholarPubMed