DNA Methylation Dynamics during In Vivo Differentiation of Blood and Skin Stem Cells. Bock, C., Beerman I., Lien WH, Smith ZD, Gu H., Boyle P., Gnirke A., Fuchs E., Rossi DJ, and Meissner A. Molecular cell, 2012/08/24, Volume 47, Issue 4, p.633-47, (2012)
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Abstract
Epigenetic obstacles encountered by transcription factors: reprogramming against all odds. Gifford, CA, and Meissner A. Current opinion in genetics & development, 2012/08/23, (2012)
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Abstract
Evidence of widespread selection on standing variation in Europe at height-associated SNPs. Turchin, MC, Chiang CW, Palmer CD, Sankararaman S., Reich D., Genetic Investigation of ANthropometric Traits(GIANT) Consortium, and Hirschhorn JN Nature genetics, 2012/08/19, Volume 44, Issue 9, p.1015-9, (2012)
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Abstract
Cancer vulnerabilities unveiled by genomic loss. Nijhawan, D., Zack TI, Ren Y., Strickland MR, Lamothe R., Schumacher SE, Tsherniak A., Besche HC, Rosenbluh J., Shehata S., Cowley GS, Weir BA, Goldberg AL, Mesirov J. P., Root DE, Bhatia SN, Beroukhim R., and Hahn WC Cell, 2012/08/17, Volume 150, Issue 4, p.842-54, (2012)
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Abstract
Candida albicans infection affords protection against reinfection via functional reprogramming of monocytes. Quintin, J., Saeed S., Martens JH, Giamarellos-Bourboulis EJ, Ifrim DC, Logie C., Jacobs L., Jansen T., Kullberg BJ, Wijmenga C., Joosten LA, Xavier RJ, van der Meer JW, Stunnenberg HG, and Netea MG Cell host & microbe, 2012/08/16, Volume 12, Issue 2, p.223-32, (2012)
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Abstract
Mild paroxysmal kinesigenic dyskinesia caused by PRRT2 missense mutation with reduced penetrance. Friedman, J., Olvera J., Silhavy JL, Gabriel SB, and Gleeson JG Neurology, 2012/08/15, (2012)
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Abstract
Targeted Tumor-Penetrating siRNA Nanocomplexes for Credentialing the Ovarian Cancer Oncogene ID4. Ren, Y., Cheung HW, von Maltzhan G., Agrawal A., Cowley GS, Weir BA, Boehm JS, Tamayo P., Karst AM, Liu JF, Hirsch MS, Mesirov J. P., Drapkin R., Root DE, Lo J., Fogal V., Ruoslahti E., Hahn WC, and Bhatia SN Science translational medicine, 2012/08/15, Volume 4, Issue 147, p.147ra112, (2012)
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Abstract
ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression. Abdel-Wahab, O., Adli M., LaFave LM, Gao J., Hricik T., Shih AH, Pandey S., Patel JP, Chung YR, Koche R., Perna F., Zhao X., Taylor JE, Park CY, Carroll M., Melnick A., Nimer SD, Jaffe JD, Aifantis I., Bernstein BE, et al. Cancer cell, 2012/08/14, Volume 22, Issue 2, p.180-93, (2012)
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Abstract
Genome-wide association study of Tourette's syndrome. Scharf, JM, Yu D., Mathews CA, Neale BM, Stewart SE, Fagerness JA, Evans P., Gamazon E., Edlund CK, Service SK, Tikhomirov A., Osiecki L., Illmann C., Pluzhnikov A., Konkashbaev A., Davis LK, Han B., Crane J., Moorjani P., Crenshaw AT, et al. Molecular psychiatry, 2012/08/14, (2012)
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Abstract
Phasing of many thousands of genotyped samples. Williams, AL, Patterson N., Glessner J., Hakonarson H., and Reich D. American journal of human genetics, 2012/08/10, Volume 91, Issue 2, p.238-51, (2012)
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Abstract
Synthesis and Profiling of a Diverse Collection of Azetidine-Based Scaffolds for the Development of CNS-Focused Lead-like Libraries. Lowe, JT, Lee MD 4th, Akella LB, Davoine E., Donckele EJ, Durak L., Duvall JR, Gerard B., Holson EB, Joliton A., Kesavan S., Lemercier BC, Liu H., Marié JC, Mulrooney CA, Muncipinto G., Welzel-O'Shea M., Panko LM, Rowley A., Suh BC, et al. The Journal of organic chemistry, 2012/08/10, (2012)
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Abstract
Sequence-based association and selection scans identify drug resistance loci in the Plasmodium falciparum malaria parasite. Park, DJ, Lukens AK, Neafsey DE, Schaffner SF, Chang HH, Valim C., Ribacke U., Van Tyne D., Galinsky K., Galligan M., Becker JS, Ndiaye D., Mboup S., Wiegand RC, Hartl DL, Sabeti PC, Wirth DF, and Volkman SK Proceedings of the National Academy of Sciences of the United States of America, 2012/08/07, Volume 109, Issue 32, p.13052-7, (2012)
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Abstract
Identification of regulators of polyploidization presents therapeutic targets for treatment of AMKL. Wen, Q., Goldenson B., Silver SJ, Schenone M., Dancik V., Huang Z., Wang LZ, Lewis TA, An WF, Li X., Bray MA, Thiollier C., Diebold L., Gilles L., Vokes MS, Moore CB, Bliss-Moreau M., VerPlank L., Tolliday NJ, Mishra R., et al. Cell, 2012/08/03, Volume 150, Issue 3, p.575-89, (2012)
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Abstract
Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations. Pugh, TJ, Weeraratne SD, Archer TC, Pomeranz Krummel DA, Auclair D., Bochicchio J., Carneiro MO, Carter SL, Cibulskis K., Erlich RL, Greulich H., Lawrence MS, Lennon NJ, McKenna A., Meldrim J., Ramos AH, Ross MG, Russ C., Shefler E., Sivachenko A., et al. Nature, 2012/08/02, Volume 488, Issue 7409, p.106-10, (2012)
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Abstract
The human microbiome project: a community resource for the healthy human microbiome. Gevers, D., Knight R., Petrosino JF, Huang K., McGuire AL, Birren BW, Nelson KE, White O., Methé BA, and Huttenhower C. PLoS biology, 2012/08/01, Volume 10, Issue 8, p.e1001377, (2012)
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Abstract
The metabochip, a custom genotyping array for genetic studies of metabolic, cardiovascular, and anthropometric traits. Voight, BF, Kang HM, Ding J., Palmer CD, Sidore C., Chines PS, Burtt NP, Fuchsberger C., Li Y., Erdmann J., Frayling TM, Heid IM, Jackson AU, Johnson T., Kilpeläinen TO, Lindgren CM, Morris AP, Prokopenko I., Randall JC, Saxena R., et al. PLoS genetics, 2012/08/01, Volume 8, Issue 8, p.e1002793, (2012)
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Abstract
Cis-acting regulation of brain-specific ANK3 gene expression by a genetic variant associated with bipolar disorder. Rueckert, EH, Barker D., Ruderfer D., Bergen SE, O'Dushlaine C., Luce CJ, Sheridan SD, Theriault KM, Chambert K., Moran J., Purcell SM, Madison JM, Haggarty SJ, and Sklar P. Molecular psychiatry, 2012/07/31, (2012)
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Abstract
Novel, panzootic and hybrid genotypes of amphibian chytridiomycosis associated with the bullfrog trade. Schloegel, LM, Toledo LF, Longcore JE, Greenspan SE, Vieira CA, Lee M., Zhao S., Wangen C., Ferreira CM, Hipolito M., Davies AJ, Cuomo CA, Daszak P., and James TY Molecular ecology, 2012/07/31, (2012)
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Abstract
Resistance to EGFR blockade in colorectal cancer: liquid biopsies and latent subclones. Konieczkowski, DJ, and Garraway LA Cell research, 2012/07/31, (2012)
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Abstract
New mechanisms of 5-nitrofuran toxicity. Peterson, RT Chemistry & biology, 2012/07/27, Volume 19, Issue 7, p.789-90, (2012)
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Abstract
zCall: A Rare Variant Caller for Array-based Genotyping. Goldstein, JI, Crenshaw A., Carey J., Grant G., Maguire J., Fromer M., O'Dushlaine C., Moran JL, Chambert K., Stevens C., Swedish Schizophrenia Consortium, ARRA Autism Sequencing Consortium, Sklar P., Hultman CM, Purcell S., McCarroll S., Sullivan PF, Daly M. J., and Neale BM Bioinformatics (Oxford, England), 2012/07/27, (2012)
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Abstract
Comprehensive interrogation of natural TALE DNA-binding modules and transcriptional repressor domains. Cong, L., Zhou R., Kuo YC, Cunniff M., and Zhang F. Nature communications, 2012/07/24, Volume 3, p.968, (2012)
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Abstract
Eradication of bacterial persisters with antibiotic-generated hydroxyl radicals. Grant, SS, Kaufmann BB, Chand NS, Haseley N., and Hung DT Proceedings of the National Academy of Sciences of the United States of America, 2012/07/24, Volume 109, Issue 30, p.12147-52, (2012)
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Abstract
Finished bacterial genomes from shotgun sequence data. Ribeiro, F., Przybylski D., Yin S., Sharpe T., Gnerre S., Abouelleil A., Berlin AM, Montmayeur A., Shea TP, Walker BJ, Young SK, Russ C., Maccallum I., Nusbaum C., and Jaffe DB Genome research, 2012/07/24, (2012)
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Abstract
Concordance and Discordance in Tumor Genomic Profiling. Garraway, LA Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012/07/23, (2012)
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A landscape of driver mutations in melanoma. Hodis, E., Watson IR, Kryukov GV, Arold ST, Imielinski M., Theurillat JP, Nickerson E., Auclair D., Li L., Place C., Dicara D., Ramos AH, Lawrence MS, Cibulskis K., Sivachenko A., Voet D., Saksena G., Stransky N., Onofrio RC, Winckler W., et al. Cell, 2012/07/20, Volume 150, Issue 2, p.251-63, (2012)
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Abstract
Microsporidian genome analysis reveals evolutionary strategies for obligate intracellular growth. Cuomo, CA, Desjardins CA, Bakowski MA, Goldberg J., Ma AT, Becnel JJ, Didier ES, Fan L., Heiman DI, Levin JZ, Young S., Zeng Q., and Troemel ER Genome research, 2012/07/18, (2012)
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Abstract
Paired-end sequencing of Fosmid libraries by Illumina. Williams, LJ, Tabbaa DG, Li N., Berlin AM, Shea TP, Maccallum I., Lawrence MS, Drier Y., Getz G., Young SK, Jaffe DB, Nusbaum C., and Gnirke A. Genome research, 2012/07/17, (2012)
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Abstract
A remarkably simple genome underlies highly malignant pediatric rhabdoid cancers. Lee, RS, Stewart C., Carter SL, Ambrogio L., Cibulskis K., Sougnez C., Lawrence MS, Auclair D., Mora J., Golub T. R., Biegel JA, Getz G., and Roberts CW The Journal of clinical investigation, 2012/07/16, (2012)
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Abstract
Wisdom of crowds for robust gene network inference. Marbach, D., Costello JC, Küffner R., Vega NM, Prill RJ, Camacho DM, Allison KR, The DREAM5 Consortium, Aderhold A., Allison KR, Bonneau R., Camacho DM, Chen Y., Collins JJ, Cordero F., Costello JC, Crane M., Dondelinger F., Drton M., Esposito R., et al. Nature methods, 2012/07/15, (2012)
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Abstract
Reconstructing Native American population history. Reich, D., Patterson N., Campbell D., Tandon A., Mazieres S., Ray N., Parra MV, Rojas W., Duque C., Mesa N., García LF, Triana O., Blair S., Maestre A., Dib JC, Bravi CM, Bailliet G., Corach D., Hünemeier T., Bortolini MC, et al. Nature, 2012/07/11, (2012)
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Abstract
Untuning the tumor metabolic machine: Targeting cancer metabolism: a bedside lesson. Birsoy, K., Sabatini DM, and Possemato R. Nature medicine, 2012/07/06, Volume 18, Issue 7, p.1022-3, (2012)
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Crebinostat: A novel cognitive enhancer that inhibits histone deacetylase activity and modulates chromatin-mediated neuroplasticity. Fass, DM, Reis SA, Ghosh B., Hennig KM, Joseph NF, Zhao WN, Nieland TJ, Guan JS, Groves Kuhnle CE, Tang W., Barker DD, Mazitschek R., Schreiber SL, Tsai LH, and Haggarty SJ Neuropharmacology, 2012/07/04, (2012)
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Abstract
Strain-Specific Regulation of Striatal Phenotype in Drd2-eGFP BAC Transgenic Mice. Chan, CS, Peterson JD, Gertler TS, Glajch KE, Quintana RE, Cui Q., Sebel LE, Plotkin JL, Shen W., Heiman M., Heintz N., Greengard P., and Surmeier DJ The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012/07/04, Volume 32, Issue 27, p.9124-9132, (2012)
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Abstract
Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion. Straussman, R., Morikawa T., Shee K., Barzily-Rokni M., Qian ZR, Du J., Davis A., Mongare MM, Gould J., Frederick DT, Cooper ZA, Chapman PB, Solit DB, Ribas A., Lo RS, Flaherty KT, Ogino S., Wargo JA, and Golub T. R. Nature, 2012/07/04, (2012)
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Abstract
Exome sequencing identifies GATA1 mutations resulting in Diamond-Blackfan anemia. Sankaran, VG, Ghazvinian R., Do R., Thiru P., Vergilio JA, Beggs AH, Sieff CA, Orkin SH, Nathan DG, Lander E. S., and Gazda HT The Journal of clinical investigation, 2012/07/02, Volume 122, Issue 7, p.2439-43, (2012)
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Abstract
Efficiency and power as a function of sequence coverage, SNP array density, and imputation. Flannick, J., Korn JM, Fontanillas P., Grant GB, Banks E., DePristo MA, and Altshuler D. PLoS computational biology, 2012/07/01, Volume 8, Issue 7, p.e1002604, (2012)
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Abstract
Structural haplotypes and recent evolution of the human 17q21.31 region. Boettger, LM, Handsaker RE, Zody MC, and McCarroll SA Nature genetics, 2012/07/01, (2012)
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Abstract
The uncertain road towards genomic medicine. Macarthur, DG, and Lek M. Trends in genetics : TIG, 2012/07/01, Volume 28, Issue 7, p.303-5, (2012)
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Abstract
Annotated high-throughput microscopy image sets for validation. Ljosa, V., Sokolnicki KL, and Carpenter AE Nature methods, 2012/06/28, Volume 9, Issue 7, p.637, (2012)
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A call for bioimaging software usability. Carpenter, AE, Kamentsky L., and Eliceiri KW Nature methods, 2012/06/28, Volume 9, Issue 7, p.666-70, (2012)
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Amino acids and mTORC1: from lysosomes to disease. Efeyan, A., Zoncu R., and Sabatini DM Trends in molecular medicine, 2012/06/27, (2012)
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Abstract
Iterative capped assembly: rapid and scalable synthesis of repeat-module DNA such as TAL effectors from individual monomers. Briggs, AW, Rios X., Chari R., Yang L., Zhang F., Mali P., and Church GM Nucleic acids research, 2012/06/26, (2012)
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Abstract
Genomic sequencing of Plasmodium falciparum malaria parasites from Senegal reveals the demographic history of the population. Chang, HH, Park DJ, Galinsky KJ, Schaffner SF, Ndiaye D., Ndir O., Mboup S., Wiegand RC, Volkman SK, Sabeti PC, Wirth DF, Neafsey DE, and Hartl DL Molecular biology and evolution, 2012/06/24, (2012)
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Abstract
Inhibition of histone deacetylase 3 protects Beta cells from cytokine-induced apoptosis. Chou, DH, Holson EB, Wagner FF, Tang AJ, Maglathlin RL, Lewis TA, Schreiber SL, and Wagner BK Chemistry & biology, 2012/06/22, Volume 19, Issue 6, p.669-73, (2012)
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Abstract
Sequence analysis of mutations and translocations across breast cancer subtypes. Banerji, S., Cibulskis K., Rangel-Escareno C., Brown KK, Carter SL, Frederick AM, Lawrence MS, Sivachenko AY, Sougnez C., Zou L., Cortes ML, Fernandez-Lopez JC, Peng S., Ardlie KG, Auclair D., Bautista-Piña V., Duke F., Francis J., Jung J., Maffuz-Aziz A., et al. Nature, 2012/06/20, Volume 486, Issue 7403, p.405-9, (2012)
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Abstract
Activity-dependent A-to-I RNA Editing in Rat Cortical Neurons. Sanjana, NE, Levanon EY, Hueske EA, Ambrose JM, and Li JB Genetics, 2012/06/19, (2012)
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Abstract
Efficient algorithms for the reconciliation problem with gene duplication, horizontal transfer and loss. Bansal, MS, Alm EJ, and Kellis M. Bioinformatics (Oxford, England), 2012/06/15, Volume 28, Issue 12, p.i283-i291, (2012)
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Abstract
The promise and perils of stem cell therapeutics. Daley, GQ Cell stem cell, 2012/06/14, Volume 10, Issue 6, p.740-9, (2012)
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Abstract
Integrative Genomic Analysis Implicates Gain of PIK3CA at 3q26 and MYC at 8q24 in Chronic Lymphocytic Leukemia. Brown, JR, Hanna M., Tesar B., Werner L., Pochet N., Asara JM, Wang YE, Dal Cin P., Fernandes SM, Thompson C., MacConaill L., Wu CJ, Van de Peer Y., Correll M., Regev A., Neuberg D., and Freedman AS Clinical cancer research : an official journal of the American Association for Cancer Research, 2012/06/13, (2012)
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Abstract
Genetic polymorphisms for estimating risk of atrial fibrillation: a literature-based meta-analysis. Gustav Smith, J., Almgren P., Engström G., Hedblad B., Platonov PG, Newton-Cheh C., and Melander O. Journal of internal medicine, 2012/06/12, (2012)
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Abstract
Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder. Bergen, SE, O'Dushlaine CT, Ripke S., Lee PH, Ruderfer DM, Akterin S., Moran JL, Chambert KD, Handsaker RE, Backlund L., Osby U., McCarroll S., Landen M., Scolnick EM, Magnusson PK, Lichtenstein P., Hultman CM, Purcell SM, Sklar P., and Sullivan PF Molecular psychiatry, 2012/06/12, (2012)
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Abstract
Highly efficient generation of heritable zebrafish gene mutations using homo- and heterodimeric TALENs. Cade, L., Reyon D., Hwang WY, Tsai SQ, Patel S., Khayter C., Joung JK, Sander JD, Peterson RT, and Yeh JR Nucleic acids research, 2012/06/07, (2012)
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Abstract
The Role of Genetic Markers in the Management of Prostate Cancer. Choudhury, AD, Eeles R., Freedland SJ, Isaacs WB, Pomerantz MM, Schalken JA, Tammela TL, and Visakorpi T. European urology, 2012/06/05, (2012)
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Abstract
Attenuation of notch and hedgehog signaling is required for fate specification in the spinal cord. Huang, P., Xiong F., Megason SG, and Schier AF PLoS genetics, 2012/06/01, Volume 8, Issue 6, p.e1002762, (2012)
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Abstract
Dosage and tumour suppression. Berger, AH, Knudson AG, and Pandolfi PP The Journal of pathology, 2012/06/01, Volume 227, Issue 2, p.e1, (2012)
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Identifying gnostic predictors of the vaccine response. Haining, WN, and Pulendran B. Current opinion in immunology, 2012/06/01, Volume 24, Issue 3, p.332-6, (2012)
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Abstract
RNA-SeQC: RNA-seq metrics for quality control and process optimization. Deluca, DS, Levin JZ, Sivachenko A., Fennell T., Nazaire MD, Williams C., Reich M., Winckler W., and Getz G. Bioinformatics (Oxford, England), 2012/06/01, Volume 28, Issue 11, p.1530-2, (2012)
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Abstract
Behavioral barcoding in the cloud: embracing data-intensive digital phenotyping in neuropharmacology. Kokel, D., Rennekamp AJ, Shah AH, Liebel U., and Peterson RT Trends in biotechnology, 2012/05/29, (2012)
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Abstract
Cooperative interactions of BRAFV600E kinase and CDKN2A locus deficiency in pediatric malignant astrocytoma as a basis for rational therapy. Huillard, E., Hashizume R., Phillips JJ, Griveau A., Ihrie RA, Aoki Y., Nicolaides T., Perry A., Waldman T., McMahon M., Weiss WA, Petritsch C., James CD, and Rowitch DH Proceedings of the National Academy of Sciences of the United States of America, 2012/05/29, Volume 109, Issue 22, p.8710-5, (2012)
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Abstract
Exome sequencing and the genetic basis of complex traits. Kiezun, A., Garimella K., Do R., Stitziel NO, Neale BM, McLaren PJ, Gupta N., Sklar P., Sullivan PF, Moran JL, Hultman CM, Lichtenstein P., Magnusson P., Lehner T., Shugart YY, Price AL, de Bakker PI, Purcell SM, and Sunyaev SR Nature genetics, 2012/05/29, Volume 44, Issue 6, p.623-30, (2012)
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Exploring the variation within. Macosko, EZ, and McCarroll SA Nature genetics, 2012/05/29, Volume 44, Issue 6, p.614-6, (2012)
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Abstract
A Keystone for ncRNA. Hacisuleyman, E., Cabili MN, and Rinn JL Genome biology, 2012/05/25, Volume 13, Issue 5, p.315, (2012)
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Abstract
Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation. Jain, M., Nilsson R., Sharma S., Madhusudhan N., Kitami T., Souza AL, Kafri R., Kirschner MW, Clish CB, and Mootha VK Science (New York, N.Y.), 2012/05/25, Volume 336, Issue 6084, p.1040-4, (2012)
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Abstract
Identification of Novel Inhibitors of M. tuberculosis Growth Using Whole Cell Based High-Throughput Screening. Stanley, SA, Grant SS, Kawate T., Iwase N., Shimizu M., Wivagg C., Silvis M., Kazyanskaya E., Aquadro J., Golas A., FitzGerald M., Dai H., Zhang L., and Hung DT ACS chemical biology, 2012/05/21, (2012)
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Abstract
Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer. Barbieri, CE, Baca SC, Lawrence MS, Demichelis F., Blattner M., Theurillat JP, White TA, Stojanov P., Van Allen E., Stransky N., Nickerson E., Chae SS, Boysen G., Auclair D., Onofrio RC, Park K., Kitabayashi N., MacDonald TY, Sheikh K., Vuong T., et al. Nature genetics, 2012/05/20, Volume 44, Issue 6, p.685-9, (2012)
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Abstract
Extremely low-coverage sequencing and imputation increases power for genome-wide association studies. Pasaniuc, B., Rohland N., McLaren PJ, Garimella K., Zaitlen N., Li H., Gupta N., Neale BM, Daly M. J., Sklar P., Sullivan PF, Bergen S., Moran JL, Hultman CM, Lichtenstein P., Magnusson P., Purcell SM, Haas DW, Liang L., Sunyaev S., et al. Nature genetics, 2012/05/20, Volume 44, Issue 6, p.631-5, (2012)
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Abstract
mTORC1 in the Paneth cell niche couples intestinal stem-cell function to calorie intake. Yilmaz, OH, Katajisto P., Lamming DW, Gültekin Y., Bauer-Rowe KE, Sengupta S., Birsoy K., Dursun A., Yilmaz VO, Selig M., Nielsen GP, Mino-Kenudson M., Zukerberg LR, Bhan AK, Deshpande V., and Sabatini DM Nature, 2012/05/20, (2012)
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Abstract
Evolutionary diversity of the mitochondrial calcium uniporter. Bick, AG, Calvo SE, and Mootha VK Science (New York, N.Y.), 2012/05/18, Volume 336, Issue 6083, p.886, (2012)
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Abstract
Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study. Voight, BF, Peloso GM, Orho-Melander M., Frikke-Schmidt R., Barbalic M., Jensen MK, Hindy G., Hólm H., Ding EL, Johnson T., Schunkert H., Samani NJ, Clarke R., Hopewell JC, Thompson JF, Li M., Thorleifsson G., Newton-Cheh C., Musunuru K., Pirruccello JP, et al. Lancet, 2012/05/17, (2012)
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Abstract
Identification of a selective small molecule inhibitor of breast cancer stem cells. Germain, AR, Carmody LC, Morgan B., Fernandez C., Forbeck E., Lewis TA, Nag PP, Ting A., VerPlank L., Feng Y., Perez JR, Dandapani S., Palmer M., Lander E. S., Gupta PB, Schreiber SL, and Munoz B. Bioorganic & medicinal chemistry letters, 2012/05/15, Volume 22, Issue 10, p.3571-4, (2012)
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Abstract
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Manning, AK, Hivert MF, Scott RA, Grimsby JL, Bouatia-Naji N., Chen H., Rybin D., Liu CT, Bielak LF, Prokopenko I., Amin N., Barnes D., Cadby G., Hottenga JJ, Ingelsson E., Jackson AU, Johnson T., Kanoni S., Ladenvall C., Lagou V., et al. Nature genetics, 2012/05/13, Volume 44, Issue 6, p.659-669, (2012)
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Abstract
Melanoma genome sequencing reveals frequent PREX2 mutations. Berger, MF, Hodis E., Heffernan TP, Deribe YL, Lawrence MS, Protopopov A., Ivanova E., Watson IR, Nickerson E., Ghosh P., Zhang H., Zeid R., Ren X., Cibulskis K., Sivachenko AY, Wagle N., Sucker A., Sougnez C., Onofrio R., Ambrogio L., et al. Nature, 2012/05/09, Volume 485, Issue 7399, p.502-6, (2012)
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Abstract
Apoptotic Cells Are Cleared by Directional Migration and elmo1- Dependent Macrophage Engulfment. van Ham, TJ, Kokel D., and Peterson RT Current biology : CB, 2012/05/08, Volume 22, Issue 9, p.830-6, (2012)
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Abstract
Exploring single-sample SNP and INDEL calling with whole-genome de novo assembly. Li, H. Bioinformatics (Oxford, England), 2012/05/07, (2012)
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Abstract
A Method of Moments Estimator for Random Effect Multivariate Meta-Analysis. Chen, H., Manning AK, and Dupuis J. Biometrics, 2012/05/02, (2012)
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Abstract
Expression of the p53 Target CDIP Correlates with Sensitivity to TNFα-Induced Apoptosis in Cancer Cells. Brown-Endres, L., Schoenfeld D., Tian F., Kim HG, Namba T., Muñoz-Fontela C., Mandinova A., Aaronson SA, and Lee SW Cancer research, 2012/05/01, Volume 72, Issue 9, p.2373-82, (2012)
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Abstract
Modification site localization scoring: strategies and performance. Chalkley, RJ, and Clauser KR Molecular & cellular proteomics : MCP, 2012/05/01, Volume 11, Issue 5, p.3-14, (2012)
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Abstract
Overcoming fluconazole resistance in Candida albicans clinical isolates with tetracyclic indoles. Youngsaye, W., Dockendorff C., Vincent B., Hartland CL, Bittker JA, Dandapani S., Palmer M., Whitesell L., Lindquist S., Schreiber SL, and Munoz B. Bioorganic & medicinal chemistry letters, 2012/05/01, Volume 22, Issue 9, p.3362-5, (2012)
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Abstract
A Small-Molecule Probe of the Histone Methyltransferase G9a Induces Cellular Senescence in Pancreatic Adenocarcinoma. Yuan, Y., Wang Q., Paulk J., Kubicek S., Kemp MM, Adams DJ, Shamji AF, Wagner BK, and Schreiber SL ACS chemical biology, 2012/04/30, (2012)
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Abstract
Absolute quantification of somatic DNA alterations in human cancer. Carter, SL, Cibulskis K., Helman E., McKenna A., Shen H., Zack T., Laird PW, Onofrio RC, Winckler W., Weir BA, Beroukhim R., Pellman D., Levine DA, Lander E. S., Meyerson M., and Getz G. Nature biotechnology, 2012/04/29, (2012)
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Abstract
Reduced Expression of Ribosomal Proteins Relieves MicroRNA-Mediated Repression. Janas, MM, Wang E., Love T., Harris AS, Stevenson K., Semmelmann K., Shaffer JM, Chen PH, Doench JG, Yerramilli SV, Neuberg DS, Iliopoulos D., Housman DE, Burge CB, and Novina CD Molecular cell, 2012/04/27, Volume 46, Issue 2, p.171-86, (2012)
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Abstract
Sequencing Chromosomal Abnormalities Reveals Neurodevelopmental Loci that Confer Risk across Diagnostic Boundaries. Talkowski, ME, Rosenfeld JA, Blumenthal I., Pillalamarri V., Chiang C., Heilbut A., Ernst C., Hanscom C., Rossin E., Lindgren AM, Pereira S., Ruderfer D., Kirby A., Ripke S., Harris DJ, Lee JH, Ha K., Kim HG, Solomon BD, Gropman AL, et al. Cell, 2012/04/27, Volume 149, Issue 3, p.525-37, (2012)
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Abstract
Apolipoprotein E Genotype Predicts Hematoma Expansion in Lobar Intracerebral Hemorrhage. Brouwers, HB, Biffi A., Ayres AM, Schwab K., Cortellini L., Romero JM, Rost NS, Viswanathan A., Greenberg SM, Rosand J., and Goldstein JN Stroke; a journal of cerebral circulation, 2012/04/24, (2012)
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Abstract
Sex-specific influence of DRD2 on ADHD-type temperament in a large population-based birth cohort. Nyman, ES, Loukola A., Varilo T., Taanila A., Hurtig T., Moilanen I., Loo S., McGough JJ, Järvelin MR, Smalley SL, Nelson SF, and Peltonen L. Psychiatric genetics, 2012/04/23, (2012)
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Abstract
An image analysis toolbox for high-throughput C. elegans assays. Wählby, C., Kamentsky L., Liu ZH, Riklin-Raviv T., Conery AL, O'Rourke EJ, Sokolnicki KL, Visvikis O., Ljosa V., Irazoqui JE, Golland P., Ruvkun G., Ausubel FM, and Carpenter AE Nature methods, 2012/04/22, (2012)
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Abstract
Not lost in translation: stepwise regulation of microRNA targets. Janas, MM, and Novina CD The EMBO journal, 2012/04/20, (2012)
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Chemical Genomics Identifies Small-Molecule MCL1 Repressors and BCL-xL as a Predictor of MCL1 Dependency. Wei, G., Margolin AA, Haery L., Brown E., Cucolo L., Julian B., Shehata S., Kung AL, Beroukhim R., and Golub T. R. Cancer cell, 2012/04/17, Volume 21, Issue 4, p.547-62, (2012)
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Abstract
INRICH: Interval-based Enrichment Analysis for Genome Wide Association Studies. Lee, PH, O'Dushlaine C., Thomas B., and Purcell SM Bioinformatics (Oxford, England), 2012/04/17, (2012)
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Abstract
RNA signatures allow rapid identification of pathogens and antibiotic susceptibilities. Barczak, AK, Gomez JE, Kaufmann BB, Hinson ER, Cosimi L., Borowsky ML, Onderdonk AB, Stanley SA, Kaur D., Bryant KF, Knipe DM, Sloutsky A., and Hung DT Proceedings of the National Academy of Sciences of the United States of America, 2012/04/17, Volume 109, Issue 16, p.6217-22, (2012)
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Abstract
Impact of PNKP mutations associated with microcephaly, seizures and developmental delay on enzyme activity and DNA strand break repair. Reynolds, JJ, Walker AK, Gilmore EC, Walsh CA, and Caldecott KW Nucleic acids research, 2012/04/15, (2012)
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Abstract
pIRS: Profile based Illumina pair-end Reads Simulator. Hu, X., Yuan J., Shi Y., Lu J., Liu B., Li Z., Chen Y., Mu D., Zhang H., Li N., Yue Z., Bai F., Li H., and An WF Bioinformatics (Oxford, England), 2012/04/15, (2012)
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Abstract
Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. Udeshi, ND, Mani D. R., Eisenhaure T., Mertins P., Jaffe JD, Clauser KR, Hacohen N., and Carr SA Molecular & cellular proteomics : MCP, 2012/04/14, (2012)
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Abstract
Harnessing genomics and genome biology to understand malaria biology. Volkman, SK, Neafsey DE, Schaffner SF, Park DJ, and Wirth DF Nature reviews. Genetics, 2012/04/12, Volume 13, Issue 5, p.315-28, (2012)
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Abstract
Parametric modeling of cellular state transitions as measured with flow cytometry. Ho, HJ, Lin TI, Chang HH, Haase SB, Huang S., and Pyne S. BMC bioinformatics, 2012/04/12, Volume 13 Suppl 5, p.S5, (2012)
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Abstract
Fast and accurate inference of local ancestry in Latino populations. Baran, Y., Pasaniuc B., Sankararaman S., Torgerson DG, Gignoux C., Eng C., Rodriguez-Cintron W., Chapela R., Ford JG, Avila PC, Rodriguez-Santana J., Burchard EG, and Halperin E. Bioinformatics (Oxford, England), 2012/04/11, (2012)
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Abstract
Alzheimer Disease Susceptibility Loci: Evidence for a Protein Network under Natural Selection. Raj, T., Shulman JM, Keenan BT, Chibnik LB, Evans DA, Bennett DA, Stranger BE, and De Jager PL American journal of human genetics, 2012/04/06, Volume 90, Issue 4, p.720-6, (2012)
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Abstract
The genomic basis of adaptive evolution in threespine sticklebacks. Jones, FC, Grabherr MG, Chan YF, Russell P., Mauceli E., Johnson J., Swofford R., Pirun M., Zody MC, White S., Birney E., Searle S., Schmutz J., Grimwood J., Dickson MC, Myers RM, Miller CT, Summers BR, Knecht AK, Brady SD, et al. Nature, 2012/04/04, Volume 484, Issue 7392, p.55-61, (2012)
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Abstract
Patterns and rates of exonic de novo mutations in autism spectrum disorders. Neale, BM, Kou Y., Liu L., Ma'ayan A., Samocha KE, Sabo A., Lin CF, Stevens C., Wang LS, Makarov V., Polak P., Yoon S., Maguire J., Crawford EL, Campbell NG, Geller ET, Valladares O., Schafer C., Liu H., Zhao T., et al. Nature, 2012/04/04, (2012)
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Abstract
Chromatin-targeting small molecules cause class-specific transcriptional changes in pancreatic endocrine cells. Kubicek, S., Gilbert JC, Fomina-Yadlin D., Gitlin AD, Yuan Y., Wagner FF, Holson EB, Luo T., Lewis TA, Taylor B., Gupta S., Shamji AF, Wagner BK, Clemons PA, and Schreiber SL Proceedings of the National Academy of Sciences of the United States of America, 2012/04/03, Volume 109, Issue 14, p.5364-9, (2012)
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Abstract
