Publications

Failure to replicate a genetic signal for sex bias in the steppe migration into central Europe.

Lazaridis I, Reich D. Failure to replicate a genetic signal for sex bias in the steppe migration into central Europe. Proc Natl Acad Sci U S A. 2017;114(20):E3873-E3874. doi:10.1073/pnas.1704308114.

Suppressors and activators of JAK-STAT signaling at diagnosis and relapse of acute lymphoblastic leukemia in Down syndrome.

Schwartzman O, Savino AMaria, Gombert M, et al. Suppressors and activators of JAK-STAT signaling at diagnosis and relapse of acute lymphoblastic leukemia in Down syndrome. Proc Natl Acad Sci U S A. 2017;114(20):E4030-E4039. doi:10.1073/pnas.1702489114.

Self-organized developmental patterning and differentiation in cerebral organoids.

Renner M, Lancaster MA, Bian S, et al. Self-organized developmental patterning and differentiation in cerebral organoids. EMBO J. 2017;36(10):1316-1329. doi:10.15252/embj.201694700.

Identification of Highly Specific Diversity-Oriented Synthesis-Derived Inhibitors of Clostridium difficile.

Duvall JR, Bedard L, Naylor-Olsen AM, et al. Identification of Highly Specific Diversity-Oriented Synthesis-Derived Inhibitors of Clostridium difficile. ACS Infect Dis. 2017;3(5):349-359. doi:10.1021/acsinfecdis.6b00206.

Human pluripotent stem cells recurrently acquire and expand dominant negative P53 mutations.

Merkle FT, Ghosh S, Kamitaki N, et al. Human pluripotent stem cells recurrently acquire and expand dominant negative P53 mutations. Nature. 2017;545(7653):229-233. doi:10.1038/nature22312.

Gut Microbiome Function Predicts Response to Anti-integrin Biologic Therapy in Inflammatory Bowel Diseases.

Ananthakrishnan AN, Luo C, Yajnik V, et al. Gut Microbiome Function Predicts Response to Anti-integrin Biologic Therapy in Inflammatory Bowel Diseases. Cell Host Microbe. 2017;21(5):603-610.e3. doi:10.1016/j.chom.2017.04.010.

CRISPR/Cas9 Screens Reveal Epstein-Barr Virus-Transformed B Cell Host Dependency Factors.

Ma Y, Walsh MJ, Bernhardt K, et al. CRISPR/Cas9 Screens Reveal Epstein-Barr Virus-Transformed B Cell Host Dependency Factors. Cell Host Microbe. 2017;21(5):580-591.e7. doi:10.1016/j.chom.2017.04.005.

Phenome-wide scanning identifies multiple diseases and disease severity phenotypes associated with HLA variants.

Karnes JH, Bastarache L, Shaffer CM, et al. Phenome-wide scanning identifies multiple diseases and disease severity phenotypes associated with HLA variants. Sci Transl Med. 2017;9(389). doi:10.1126/scitranslmed.aai8708.

Activation of IRF1 in Human Adipocytes Leads to Phenotypes Associated with Metabolic Disease.

Friesen M, Camahort R, Lee Y-K, et al. Activation of IRF1 in Human Adipocytes Leads to Phenotypes Associated with Metabolic Disease. Stem Cell Reports. 2017;8(5):1164-1173. doi:10.1016/j.stemcr.2017.03.014.

Control of type III protein secretion using a minimal genetic system.

Song M, Sukovich DJ, Ciccarelli L, et al. Control of type III protein secretion using a minimal genetic system. Nat Commun. 2017;8:14737. doi:10.1038/ncomms14737.