Publications
Arc Requires PSD95 for Assembly into Postsynaptic Complexes Involved with Neural Dysfunction and Intelligence. Cell Rep. 2017;21(3):679-691. doi:10.1016/j.celrep.2017.09.045.
Prolonged IKKβ Inhibition Improves Ongoing CTL Antitumor Responses by Incapacitating Regulatory T Cells. Cell Rep. 2017;21(3):578-586. doi:10.1016/j.celrep.2017.09.082.
Integrating evolutionary and regulatory information with a multispecies approach implicates genes and pathways in obsessive-compulsive disorder. Nat Commun. 2017;8(1):774. doi:10.1038/s41467-017-00831-x.
Substantial contribution of genetic variation in the expression of transcription factors to phenotypic variation revealed by eRD-GWAS. Genome Biol. 2017;18(1):192. doi:10.1186/s13059-017-1328-6.
Antibiotic efficacy-context matters. Curr Opin Microbiol. 2017;39:73-80. doi:10.1016/j.mib.2017.09.002. .
Antibodies to biotin enable large-scale detection of biotinylation sites on proteins. Nat Methods. 2017. doi:10.1038/nmeth.4465.
Phage-assisted continuous evolution of proteases with altered substrate specificity. Nat Commun. 2017;8(1):956. doi:10.1038/s41467-017-01055-9. .
A machine learning approach for predicting CRISPR-Cas9 cleavage efficiencies and patterns underlying its mechanism of action. PLoS Comput Biol. 2017;13(10):e1005807. doi:10.1371/journal.pcbi.1005807. .
Crystal structures reveal an elusive functional domain of pyrrolysyl-tRNA synthetase. Nat Chem Biol. 2017. doi:10.1038/nchembio.2497.
Continuous directed evolution of aminoacyl-tRNA synthetases. Nat Chem Biol. 2017. doi:10.1038/nchembio.2474. .