Publications

Long-range phasing of dynamic, tissue-specific and allele-specific regulatory elements.

Battaglia S, Dong K, Wu J, et al. Long-range phasing of dynamic, tissue-specific and allele-specific regulatory elements. Nat Genet. 2022;54(10):1504-1513. doi:10.1038/s41588-022-01188-8.DOI Google Scholar PubMed

In vivo CRISPR screens reveal the landscape of immune evasion pathways across cancer.

Dubrot J, Du PP, Lane-Reticker SK, et al. In vivo CRISPR screens reveal the landscape of immune evasion pathways across cancer. Nat Immunol. 2022;23(10):1495-1506. doi:10.1038/s41590-022-01315-x.DOI Google Scholar PubMed

COVID-19 Exposure Assessment Tool (CEAT): Exposure quantification based on ventilation, infection prevalence, group characteristics, and behavior.

Schimmoller BJ, Trovão NS, Isbell M, et al. COVID-19 Exposure Assessment Tool (CEAT): Exposure quantification based on ventilation, infection prevalence, group characteristics, and behavior. Sci Adv. 2022;8(39):eabq0593. doi:10.1126/sciadv.abq0593.DOI Google Scholar PubMed

High-throughput continuous evolution of compact Cas9 variants targeting single-nucleotide-pyrimidine PAMs.

Huang TP, Heins ZJ, Miller SM, et al. High-throughput continuous evolution of compact Cas9 variants targeting single-nucleotide-pyrimidine PAMs. Nat Biotechnol. 2022. doi:10.1038/s41587-022-01410-2.DOI Google Scholar PubMed

Methionine metabolism controls the B cell EBV epigenome and viral latency.

Guo R, Liang JH, Zhang Y, et al. Methionine metabolism controls the B cell EBV epigenome and viral latency. Cell Metab. 2022;34(9):1280-1297.e9. doi:10.1016/j.cmet.2022.08.008.DOI Google Scholar PubMed

Molecular convergence between Down syndrome and fragile X syndrome identified using human pluripotent stem cell models.

Susco SG, Ghosh S, Mazzucato P, et al. Molecular convergence between Down syndrome and fragile X syndrome identified using human pluripotent stem cell models. Cell Rep. 2022;40(10):111312. doi:10.1016/j.celrep.2022.111312.DOI Google Scholar PubMed

Virtual screening for small-molecule pathway regulators by image-profile matching.

Rohban MH, Fuller AM, Tan C, et al. Virtual screening for small-molecule pathway regulators by image-profile matching. Cell Syst. 2022. doi:10.1016/j.cels.2022.08.003.DOI Google Scholar PubMed

Cell type-specific inference of differential expression in spatial transcriptomics.

Cable DM, Murray E, Shanmugam V, et al. Cell type-specific inference of differential expression in spatial transcriptomics. Nat Methods. 2022. doi:10.1038/s41592-022-01575-3.DOI Google Scholar PubMed

Genetic structure correlates with ethnolinguistic diversity in eastern and southern Africa.

Atkinson EG, Dalvie S, Pichkar Y, et al. Genetic structure correlates with ethnolinguistic diversity in eastern and southern Africa. Am J Hum Genet. 2022;109(9):1667-1679. doi:10.1016/j.ajhg.2022.07.013.DOI Google Scholar PubMed

High-coverage whole-genome sequencing of the expanded 1000 Genomes Project cohort including 602 trios.

Byrska-Bishop M, Evani US, Zhao X, et al. High-coverage whole-genome sequencing of the expanded 1000 Genomes Project cohort including 602 trios. Cell. 2022;185(18):3426-3440.e19. doi:10.1016/j.cell.2022.08.004.DOI Google Scholar PubMed