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2015
COMT Val 158 Met polymorphism is associated with nonverbal cognition following mild traumatic brain injury.Winkler, EA, Yue JK, McAllister TW, Temkin NR, Oh SS, Burchard EG, Hu D., Ferguson AR, Lingsma HF, Burke JF, Sorani MD, Rosand J., Yuh EL, Barber J., Tarapore PE, Gardner RC, Sharma S., Satris GG, Eng C., Puccio AM, et al. Neurogenetics, 2015/11/17, (2015) Read More / View Supplemental Materials
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Society for Pediatric Research 2015 Young Investigator Award: Genetics of human hematopoiesis-What patients can teach us about blood cell production.Wakabayashi, A., and Sankaran VG Pediatric research, 2015/11/17, (2015) Read More / View Supplemental Materials
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Stochastic electrotransport selectively enhances the transport of highly electromobile molecules.Kim, SY, Cho JH, Murray E., Bakh N., Choi H., Ohn K., Ruelas L., Hubbert A., McCue M., Vassallo SL, Keller PJ, and Chung K. Proceedings of the National Academy of Sciences of the United States of America, 2015/11/17, Volume 112, Issue 46, p.E6274-83, (2015) Read More / View Supplemental Materials
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The contribution of rare variation to prostate cancer heritability.Mancuso, N., Rohland N., Rand KA, Tandon A., Allen A., Quinque D., Mallick S., Li H., Stram A., Sheng X., Kote-Jarai Z., Easton DF, Eeles RA, consortium Practical, Le Marchand L., Lubwama A., Stram D., Watya S., Conti DV, Henderson B., et al. Nature genetics, 2015/11/16, (2015) Read More / View Supplemental Materials
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Does developmental timing of exposure to child maltreatment predict memory performance in adulthood? Results from a large, population-based sample.Dunn, EC, Busso DS, Raffeld MR, Smoller JW, Nelson CA, Doyle AE, and Luk G. Child abuse & neglect, 2015/11/13, (2015) Read More / View Supplemental Materials
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Photoactivated Spatiotemporally-Responsive Nanosensors of in Vivo Protease Activity.Dudani, JS, Jain PK, Kwong GA, Stevens KR, and Bhatia SN ACS nano, 2015/11/13, (2015) Read More / View Supplemental Materials
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Summaries of plenary, symposia, and oral sessions at the XXII World Congress of Psychiatric Genetics, Copenhagen, Denmark, 12-16 October 2014.Aas, M., Blokland GA, Chawner SJ, Choi SW, Estrada J., Forsingdal A., Friedrich M., Ganesham S., Hall L., Haslinger D., Huckins L., Loken E., Malan-Müller S., Martin J., Misiewicz Z., Pagliaroli L., Pardiñas AF, Pisanu C., Quadri G., Santoro ML, et al. Psychiatric genetics, 2015/11/12, (2015) Read More / View Supplemental Materials
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Definitive Localization of Intracellular Proteins: Novel Approach Using CRISPR-Cas9 Genome Editing, with Glucose 6-Phosphate Dehydrogenase as a Model.Spencer, NY, Yan Z., Cong L., Zhang Y., Engelhardt JF, and Stanton RC Analytical biochemistry, 2015/11/11, (2015) Read More / View Supplemental Materials
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Expansion of Interstitial Telomeric Sequences in Yeast.Aksenova, AY, Han G., Shishkin AA, Volkov KV, and Mirkin SM Cell reports, 2015/11/11, (2015) Read More / View Supplemental Materials
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Leveraging Distant Relatedness to Quantify Human Mutation and Gene-Conversion Rates.Palamara, PF, Francioli LC, Wilton PR, Genovese G., Gusev A., Finucane HK, Sankararaman S., Genome of the Netherlands Consortium, Sunyaev SR, de Bakker PI, Wakeley J., Pe'er I., and Price AL American journal of human genetics, 2015/11/11, (2015) Read More / View Supplemental Materials
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Flow Cytometric Analysis of Mononuclear Phagocytes in Non-diseased Human Lung and Lung-draining Lymph Nodes.Desch, AN, Gibbings SL, Goyal R., Kolde R., Bednarek J., Bruno T., Slansky JE, Jacobelli J., Mason R., Ito Y., Messier E., Randolph GJ, Prabagar M., Atif SM, Segura E., Xavier RJ, Bratton DL, Janssen WJ, Henson PM, and Jakubzick CV American journal of respiratory and critical care medicine, 2015/11/09, (2015) Read More / View Supplemental Materials
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Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci.Gaulton, KJ, Ferreira T., Lee Y., Raimondo A., Mägi R., Reschen ME, Mahajan A., Locke A., William Rayner N., Robertson N., Scott RA, Prokopenko I., Scott LJ, Green T., Sparso T., Thuillier D., Yengo L., Grallert H., Wahl S., Frånberg M., et al. Nature genetics, 2015/11/09, (2015) Read More / View Supplemental Materials
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Polymorphisms of large effect explain the majority of the host genetic contribution to variation of HIV-1 virus load.McLaren, PJ, Coulonges C., Bartha I., Lenz TL, Deutsch AJ, Bashirova A., Buchbinder S., Carrington MN, Cossarizza A., Dalmau J., De Luca A., Goedert JJ, Gurdasani D., Haas DW, Herbeck JT, Johnson EO, Kirk GD, Lambotte O., Luo M., Mallal S., et al. Proceedings of the National Academy of Sciences of the United States of America, 2015/11/09, (2015) Read More / View Supplemental Materials
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Shared genetic aetiology of puberty timing between sexes and with health-related outcomes.Day, FR, Bulik-Sullivan B., Hinds DA, Finucane HK, Murabito JM, Tung JY, Ong KK, and Perry JR Nature communications, 2015/11/09, Volume 6, p.8842, (2015) Read More / View Supplemental Materials
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SWI/SNF-mutant cancers depend on catalytic and non-catalytic activity of EZH2.Kim, KH, Kim W., Howard TP, Vazquez F., Tsherniak A., Wu JN, Wang W., Haswell JR, Walensky LD, Hahn WC, Orkin SH, and Roberts CW Nature medicine, 2015/11/09, (2015) Read More / View Supplemental Materials
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Discovery and Functional Characterization of Diverse Class 2 CRISPR-Cas Systems.Shmakov, S., Abudayyeh OO, Makarova KS, Wolf YI, Gootenberg JS, Semenova E., Minakhin L., Joung J., Konermann S., Severinov K., Zhang F., and Koonin EV Molecular cell, 2015/11/05, Volume 60, Issue 3, p.385-97, (2015) Read More / View Supplemental Materials
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Draft Genome Sequence of Cercospora arachidicola, Causal Agent of Early Leaf Spot in Peanuts.Orner, VA, Cantonwine EG, Wang XM, Abouelleil A., Bochicchio J., Nusbaum C., Culbreath AK, Abdo Z., and Arias RS Genome announcements, 2015/11/05, Volume 3, Issue 6, (2015) Read More / View Supplemental Materials
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Functional implications of disease-specific variants in loci jointly associated to coeliac disease and rheumatoid arthritis.Gutierrez-Achury, J., Zorro MM, Ricaño-Ponce I., Zhernakova DV, consortium Coeliac Disease Immunochip consortium, RACI, Diogo D., Raychaudhuri S., Franke L., Trynka G., Wijmenga C., and Zhernakova A. Human molecular genetics, 2015/11/05, (2015) Read More / View Supplemental Materials
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LARS2 Variants Associated with Hydrops, Lactic Acidosis, Sideroblastic Anemia, and Multisystem Failure.Riley, LG, Rudinger-Thirion J., Schmitz-Abe K., Thorburn DR, Davis RL, Teo J., Arbuckle S., Cooper ST, Campagna DR, Frugier M., Markianos K., Sue CM, Fleming MD, and Christodoulou J. JIMD reports, 2015/11/05, (2015) Read More / View Supplemental Materials
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Two-Variance-Component Model Improves Genetic Prediction in Family Datasets.Tucker, G., Loh PR, MacLeod IM, Hayes BJ, Goddard ME, Berger B., and Price AL American journal of human genetics, 2015/11/05, Volume 97, Issue 5, p.677-90, (2015) Read More / View Supplemental Materials
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CellProfiler Tracer: exploring and validating high-throughput, time-lapse microscopy image data.Bray, MA, and Carpenter AE BMC bioinformatics, 2015/11/04, Volume 16, p.368, (2015) Read More / View Supplemental Materials
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Effect of Smoking on Blood Pressure and Resting Heart Rate: A Mendelian Randomisation Meta-Analysis in the CARTA Consortium.Linneberg, A., Jacobsen RK, Skaaby T., Taylor AE, Fluharty ME, Jeppesen JL, Bjørngaard JH, Åsvold BO, Gabrielsen ME, Campbell A., Marioni RE, Kumari M., Marques-Vidal P., Kaakinen M., Cavadino A., Postmus I., Ahluwalia TS, Wannamethee SG, Lahti J., Räikkönen K., et al. Circulation. Cardiovascular genetics, 2015/11/04, (2015) Read More / View Supplemental Materials
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Genes that Affect Brain Structure and Function Identified by Rare Variant Analyses of Mendelian Neurologic Disease.Karaca, E., Harel T., Pehlivan D., Jhangiani SN, Gambin T., Coban Akdemir Z., Gonzaga-Jauregui C., Erdin S., Bayram Y., Campbell IM, Hunter JV, Atik MM, Van Esch H., Yuan B., Wiszniewski W., Isikay S., Yesil G., Yuregir OO, Tug Bozdogan S., Aslan H., et al. Neuron, 2015/11/04, Volume 88, Issue 3, p.499-513, (2015) Read More / View Supplemental Materials
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History and genomic sequence analysis of the herpes simplex virus 1 KOS and KOS1.1 sub-strains.Colgrove, RC, Liu X., Griffiths A., Raja P., Deluca NA, Newman RM, Coen DM, and Knipe DM Virology, 2015/11/04, Volume 487, p.215-221, (2015) Read More / View Supplemental Materials
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Bactericidal Antibiotics Induce Toxic Metabolic Perturbations that Lead to Cellular Damage.Belenky, P., Ye JD, Porter CB, Cohen NR, Lobritz MA, Ferrante T., Jain S., Korry BJ, Schwarz EG, Walker GC, and Collins JJ Cell reports, 2015/11/03, Volume 13, Issue 5, p.968-80, (2015) Read More / View Supplemental Materials
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Complete Genome Sequences and Analysis of the Fusobacterium nucleatum subspecies animalis 7-1 Bacteriophage ɸFunu1 and ɸFunu2.Cochrane, K., McGuire AM, Priest ME, Abouelleil A., Cerqueira GC, Lo R., Earl AM, and Allen-Vercoe E. Anaerobe, 2015/11/03, (2015) Read More / View Supplemental Materials
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A Metabolic Signature of Mitochondrial Dysfunction Revealed through a Monogenic Form of Leigh Syndrome.Thompson Legault, J., Strittmatter L., Tardif J., Sharma R., Tremblay-Vaillancourt V., Aubut C., Boucher G., Clish CB, Cyr D., Daneault C., Waters PJ, LSFC Consortium, Vachon L., Morin C., Laprise C., Rioux JD, Mootha VK, and Des Rosiers C. Cell reports, 2015/11/03, Volume 13, Issue 5, p.981-9, (2015) Read More / View Supplemental Materials
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Characterization of Intestinal Microbiota in Ulcerative Colitis Patients with and without Primary Sclerosing Cholangitis.Kevans, D., Tyler AD, Holm K., Jørgensen KK, Vatn MH, Karlsen TH, Kaplan GG, Eksteen B., Gevers D., Hov JR, and Silverberg MS Journal of Crohn's & colitis, 2015/11/02, (2015) Read More / View Supplemental Materials
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Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis.Loh, PR, Bhatia G., Gusev A., Finucane HK, Bulik-Sullivan BK, Pollack SJ, Schizophrenia Working Group of the Psychiatric Genomics Consortium, de Candia TR, Lee SH, Wray NR, Kendler KS, O'Donovan MC, Neale BM, Patterson N., and Price AL Nature genetics, 2015/11/02, (2015) Read More / View Supplemental Materials
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Lifestyle and metformin ameliorate insulin sensitivity independently of the genetic burden of established insulin resistance variants in Diabetes Prevention Program participants.Hivert, MF, Christophi CA, Franks PW, Jablonski KA, Ehrmann DA, Kahn SE, Horton ES, Pollin TI, Mather KJ, Perreault L., Barrett-Connor E., Knowler WC, Florez JC, and Diabetes Prevention Program Research Group Diabetes, 2015/11/02, (2015) Read More / View Supplemental Materials
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50 Years of Emmonsia Disease in Humans: The Dramatic Emergence of a Cluster of Novel Fungal Pathogens.Schwartz, IS, Kenyon C., Feng P., Govender NP, Dukik K., Sigler L., Jiang Y., Stielow JB, Muñoz JF, Cuomo CA, Botha A., Stchigel AM, and de Hoog GS PLoS pathogens, 2015/11/01, Volume 11, Issue 11, p.e1005198, (2015) Read More / View Supplemental Materials
The androgen receptor cistrome is extensively reprogrammed in human prostate tumorigenesis.Pomerantz, MM, Li F., Takeda DY, Lenci R., Chonkar A., Chabot M., Cejas P., Vazquez F., Cook J., Shivdasani RA, Bowden M., Lis R., Hahn WC, Kantoff PW, Brown M., Loda M., Long HW, and Freedman ML Nature genetics, 2015/11/01, Volume 47, Issue 11, p.1346-51, (2015) Read More / View Supplemental Materials
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Calibrating the Human Mutation Rate via Ancestral Recombination Density in Diploid Genomes.Lipson, M., Loh PR, Sankararaman S., Patterson N., Berger B., and Reich D. PLoS genetics, 2015/11/01, Volume 11, Issue 11, p.e1005550, (2015) Read More / View Supplemental Materials
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Gender Disparity and Mutation Burden in Metastatic Melanoma.Gupta, S., Artomov M., Goggins W., Daly M., and Tsao H. Journal of the National Cancer Institute, 2015/11/01, Volume 107, Issue 11, (2015) Read More / View Supplemental Materials
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Genome-Wide Association Study of Golden Retrievers Identifies Germ-Line Risk Factors Predisposing to Mast Cell Tumours.Arendt, ML, Melin M., Tonomura N., Koltookian M., Courtay-Cahen C., Flindall N., Bass J., Boerkamp K., Megquir K., Youell L., Murphy S., McCarthy C., London C., Rutteman GR, Starkey M., and Lindblad-Toh K. PLoS genetics, 2015/11/01, Volume 11, Issue 11, p.e1005647, (2015) Read More / View Supplemental Materials
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The genomic landscape of juvenile myelomonocytic leukemia.Stieglitz, E., Taylor-Weiner AN, Chang TY, Gelston LC, Wang YD, Mazor T., Esquivel E., Yu A., Seepo S., Olsen SR, Rosenberg M., Archambeault SL, Abusin G., Beckman K., Brown PA, Briones M., Carcamo B., Cooper T., Dahl GV, Emanuel PD, et al. Nature genetics, 2015/11/01, Volume 47, Issue 11, p.1326-33, (2015) Read More / View Supplemental Materials
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Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair.Day, FR, Ruth KS, Thompson DJ, Lunetta KL, Pervjakova N., Chasman DI, Stolk L., Finucane HK, Sulem P., Bulik-Sullivan B., Esko T., Johnson AD, Elks CE, Franceschini N., He C., Altmaier E., Brody JA, Franke LL, Huffman JE, Keller MF, et al. Nature genetics, 2015/11/01, Volume 47, Issue 11, p.1294-303, (2015) Read More / View Supplemental Materials
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Leaderless Transcripts and Small Proteins Are Common Features of the Mycobacterial Translational Landscape.Shell, SS, Wang J., Lapierre P., Mir M., Chase MR, Pyle MM, Gawande R., Ahmad R., Sarracino DA, Ioerger TR, Fortune SM, Derbyshire KM, Wade JT, and Gray TA PLoS genetics, 2015/11/01, Volume 11, Issue 11, p.e1005641, (2015) Read More / View Supplemental Materials
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Whole-brain activity mapping onto a zebrafish brain atlas.Randlett, O., Wee CL, Naumann EA, Nnaemeka O., Schoppik D., Fitzgerald JE, Portugues R., Lacoste AM, Riegler C., Engert F., and Schier AF Nature methods, 2015/11/01, Volume 12, Issue 11, p.1039-1046, (2015) Read More / View Supplemental Materials
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Sex Differences in Plasmacytoid Dendritic Cell Levels of IRF5 Drive Higher IFN-α Production in Women.Griesbeck, M., Ziegler S., Laffont S., Smith N., Chauveau L., Tomezsko P., Sharei A., Kourjian G., Porichis F., Hart M., Palmer CD, Sirignano M., Beisel C., Hildebrandt H., Cénac C., Villani AC, Diefenbach TJ, Le Gall S., Schwartz O., Herbeuval JP, et al. Journal of immunology (Baltimore, Md. : 1950), 2015/10/30, (2015) Read More / View Supplemental Materials
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Bifidobacteria exhibit social behavior through carbohydrate resource sharing in the gut.Milani, C., Andrea Lugli G., Duranti S., Turroni F., Mancabelli L., Ferrario C., Mangifesta M., Hevia A., Viappiani A., Scholz M., Arioli S., Sanchez B., Lane J., Ward DV, Hickey R., Mora D., Segata N., Margolles A., van Sinderen D., and Ventura M. Scientific reports, 2015/10/28, Volume 5, p.15782, (2015) Read More / View Supplemental Materials
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Fluid Spatial Dynamics of West Nile Virus in the USA: Rapid Spread in a Permissive Host Environment.Di Giallonardo, F., Geoghegan JL, Docherty DE, McLean RG, Zody MC, Qu J., Yang X., Birren BW, Malboeuf CM, Newman RM, Ip HS, and Holmes EC Journal of virology, 2015/10/28, (2015) Read More / View Supplemental Materials
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Small island, big genetic discoveries.Lettre, G., and Hirschhorn JN Nature genetics, 2015/10/28, Volume 47, Issue 11, p.1224-5, (2015) Read More / View Supplemental Materials
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Genome-wide association study identifies SESTD1 as a novel risk gene for lithium-responsive bipolar disorder.Song, J., Bergen SE, Di Florio A., Karlsson R., Charney A., Ruderfer DM, Stahl EA, Members of the International Cohort Collection for Bipolar Disorder(ICCBD), Chambert KD, Moran JL, Gordon-Smith K., Forty L., Green EK, Jones I., Jones L., Scolnick EM, Sklar P., Smoller JW, Lichtenstein P., Hultman C., et al. Molecular psychiatry, 2015/10/27, (2015) Read More / View Supplemental Materials
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A perspective on stem cell modeling of Amyotrophic Lateral Sclerosis.de Boer, AS, and Eggan K. Cell cycle (Georgetown, Tex.), 2015/10/27, (2015) Read More / View Supplemental Materials
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A comparison of genetically matched cell lines reveals the equivalence of human iPSCs and ESCs.Choi, J., Lee S., Mallard W., Clement K., Tagliazucchi GM, Lim H., Choi IY, Ferrari F., Tsankov AM, Pop R., Lee G., Rinn JL, Meissner A., Park PJ, and Hochedlinger K. Nature biotechnology, 2015/10/26, (2015) Read More / View Supplemental Materials
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Genome-wide identification of microRNAs regulating cholesterol and triglyceride homeostasis.Wagschal, A., Najafi-Shoushtari SH, Wang L., Goedeke L., Sinha S., deLemos AS, Black JC, Ramírez CM, Li Y., Tewhey R., Hatoum I., Shah N., Lu Y., Kristo F., Psychogios N., Vrbanac V., Lu YC, Hla T., de Cabo R., Tsang JS, et al. Nature medicine, 2015/10/26, (2015) Read More / View Supplemental Materials
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Lenalidomide: deciphering mechanisms of action in myeloma, myelodysplastic syndrome and beyond.Guirguis, AA, and Ebert BL Current opinion in cell biology, 2015/10/26, Volume 37, p.61-67, (2015) Read More / View Supplemental Materials
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A qPCR ScoreCard quantifies the differentiation potential of human pluripotent stem cells.Tsankov, AM, Akopian V., Pop R., Chetty S., Gifford CA, Daheron L., Tsankova NM, and Meissner A. Nature biotechnology, 2015/10/26, (2015) Read More / View Supplemental Materials
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BGT: efficient and flexible genotype query across many samples.Li, H. Bioinformatics (Oxford, England), 2015/10/24, (2015) Read More / View Supplemental Materials
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Chromatin extrusion explains key features of loop and domain formation in wild-type and engineered genomes.Sanborn, AL, Rao SS, Huang SC, Durand NC, Huntley MH, Jewett AI, Bochkov ID, Chinnappan D., Cutkosky A., Li J., Geeting KP, Gnirke A., Melnikov A., McKenna D., Stamenova EK, Lander E. S., and Aiden EL Proceedings of the National Academy of Sciences of the United States of America, 2015/10/23, (2015) Read More / View Supplemental Materials
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Corrigendum: Selective killing of cancer cells by a small molecule targeting the stress response to ROS.Raj, L., Ide T., Gurkar AU, Foley M., Schenone M., Li X., Tolliday NJ, Golub T. R., Carr SA, Shamji AF, Stern AM, Mandinova A., Schreiber SL, and Lee SW Nature, 2015/10/22, Volume 526, Issue 7574, p.596, (2015) Read More / View Supplemental Materials
Genome-wide genetic homogeneity between sexes and populations for human height and body mass index.Yang, J., Bakshi A., Zhu Z., Hemani G., Vinkhuyzen AA, Nolte IM, van Vliet-Ostaptchouk JV, Snieder H., study LifeLines Cohort, Esko T., Milani L., Mägi R., Metspalu A., Hamsten A., Magnusson PK, Pedersen NL, Ingelsson E., and Visscher PM Human molecular genetics, 2015/10/22, (2015) Read More / View Supplemental Materials
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Mutations driving CLL and their evolution in progression and relapse.Landau, DA, Tausch E., Taylor-Weiner AN, Stewart C., Reiter JG, Bahlo J., Kluth S., Bozic I., Lawrence M., Böttcher S., Carter SL, Cibulskis K., Mertens D., Sougnez CL, Rosenberg M., Hess JM, Edelmann J., Kless S., Kneba M., Ritgen M., et al. Nature, 2015/10/22, Volume 526, Issue 7574, p.525-30, (2015) Read More / View Supplemental Materials
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The transcriptional landscape of age in human peripheral blood.Peters, MJ, Joehanes R., Pilling LC, Schurmann C., Conneely KN, Powell J., Reinmaa E., Sutphin GL, Zhernakova A., Schramm K., Wilson YA, Kobes S., Tukiainen T., NABEC/UKBEC Consortium, Ramos YF, Göring HH, Fornage M., Liu Y., Gharib SA, Stranger BE, et al. Nature communications, 2015/10/22, Volume 6, p.8570, (2015) Read More / View Supplemental Materials
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Calcium, TRPC channels, and regulation of the actin cytoskeleton in podocytes: towards a future of targeted therapies.Wieder, N., and Greka A. Pediatric nephrology (Berlin, Germany), 2015/10/21, (2015) Read More / View Supplemental Materials
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Genetic Diversity and Protective Efficacy of the RTS,S/AS01 Malaria Vaccine.Neafsey, DE, Juraska M., Bedford T., Benkeser D., Valim C., Griggs A., Lievens M., Abdulla S., Adjei S., Agbenyega T., Agnandji ST, Aide P., Anderson S., Ansong D., Aponte JJ, Asante KP, Bejon P., Birkett AJ, Bruls M., Connolly KM, et al. The New England journal of medicine, 2015/10/21, (2015) Read More / View Supplemental Materials
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BRAF alteration status and the histone H3F3A gene K27M mutation segregate spinal cord astrocytoma histology.Shankar, GM, Lelic N., Gill CM, Thorner AR, Van Hummelen P., Wisoff JH, Loeffler JS, Brastianos PK, Shin JH, Borges LF, Butler WE, Zagzag D., Brody RI, Duhaime AC, Taylor MD, Hawkins CE, Louis DN, Cahill DP, Curry WT, and Meyerson M. Acta neuropathologica, 2015/10/20, (2015) Read More / View Supplemental Materials
An integrative systems genetics approach reveals potential causal genes and pathways related to obesity.Kogelman, LJ, Zhernakova DV, Westra HJ, Cirera S., Fredholm M., Franke L., and Kadarmideen HN Genome medicine, 2015/10/20, Volume 7, Issue 1, p.105, (2015) Read More / View Supplemental Materials
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Oncogenic Signaling Adaptor Proteins.Luo, LY, and Hahn WC Journal of genetics and genomics = Yi chuan xue bao, 2015/10/20, Volume 42, Issue 10, p.521-9, (2015) Read More / View Supplemental Materials
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Targeted Application of Human Genetic Variation Can Improve Red Blood Cell Production from Stem Cells.Giani, FC, Fiorini C., Wakabayashi A., Ludwig LS, Salem RM, Jobaliya CD, Regan SN, Ulirsch JC, Liang G., Steinberg-Shemer O., Guo MH, Esko T., Tong W., Brugnara C., Hirschhorn JN, Weiss MJ, Zon LI, Chou ST, French DL, Musunuru K., et al. Cell stem cell, 2015/10/20, (2015) Read More / View Supplemental Materials
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Ubiquitin Ligase TRIM62 Regulates CARD9-Mediated Anti-fungal Immunity and Intestinal Inflammation.Cao, Z., Conway KL, Heath RJ, Rush JS, Leshchiner ES, Ramirez-Ortiz ZG, Nedelsky NB, Huang H., Ng A., Gardet A., Cheng SC, Shamji AF, Rioux JD, Wijmenga C., Netea MG, Means TK, Daly M. J., and Xavier RJ Immunity, 2015/10/20, Volume 43, Issue 4, p.715-26, (2015) Read More / View Supplemental Materials
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Genome sequence of the Asian Tiger mosquito, Aedes albopictus, reveals insights into its biology, genetics, and evolution.Chen, XG, Jiang X., Gu J., Xu M., Wu Y., Deng Y., Zhang C., Bonizzoni M., Dermauw W., Vontas J., Armbruster P., Huang X., Yang Y., Zhang H., He W., Peng H., Liu Y., Wu K., Chen J., Lirakis M., et al. Proceedings of the National Academy of Sciences of the United States of America, 2015/10/19, (2015) Read More / View Supplemental Materials
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Harnessing Connectivity in a Large-Scale Small-Molecule Sensitivity Dataset.Seashore-Ludlow, B., Rees MG, Cheah JH, Cokol M., Price EV, Coletti ME, Jones V., Bodycombe NE, Soule CK, Gould J., Alexander B., Li A., Montgomery P., Wawer MJ, Kuru N., Kotz JD, Hon CS, Munoz B., Liefeld T., Dančík V., et al. Cancer discovery, 2015/10/19, (2015) Read More / View Supplemental Materials
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Oct1 and OCA-B are selectively required for CD4 memory T cell function.Shakya, A., Goren A., Shalek A., German CN, Snook J., Kuchroo VK, Yosef N., Chan RC, Regev A., Williams MA, and Tantin D. The Journal of experimental medicine, 2015/10/19, (2015) Read More / View Supplemental Materials
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Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study.Cleynen, I., Boucher G., Jostins L., Schumm LP, Zeissig S., Ahmad T., Andersen V., Andrews JM, Annese V., Brand S., Brant SR, Cho JH, Daly M. J., Dubinsky M., Duerr RH, Ferguson LR, Franke A., Gearry RB, Goyette P., Hakonarson H., et al. Lancet (London, England), 2015/10/16, (2015) Read More / View Supplemental Materials
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A role for HLA-DRB1*1101 and DRB1*0801 in cognitive ability and its decline with age.Payton, A., Dawes P., Platt H., Morton CC, Moore DR, Massey J., Horan M., Ollier W., Munro KJ, and Pendleton N. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 2015/10/16, (2015) Read More / View Supplemental Materials
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Some of the most interesting CASP11 targets through the eyes of their authors.Kryshtafovych, A., Moult J., Baslé A., Burgin A., Craig TK, Edwards RA, Fass D., Hartmann MD, Korycinski M., Lewis RJ, Lorimer D., Lupas AN, Newman J., Peat TS, Piepenbrink KH, Prahlad J., van Raaij MJ, Rohwer F., Segall AM, Seguritan V., et al. Proteins, 2015/10/16, (2015) Read More / View Supplemental Materials
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Stable inhibitory activity of regulatory T cells requires the transcription factor Helios.Kim, HJ, Barnitz RA, Kreslavsky T., Brown FD, Moffett H., Lemieux ME, Kaygusuz Y., Meissner T., Holderried TA, Chan S., Kastner P., Haining WN, and Cantor H. Science (New York, N.Y.), 2015/10/16, Volume 350, Issue 6258, p.334-9, (2015) Read More / View Supplemental Materials
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Building the foundation for genomics in precision medicine.Aronson, SJ, and Rehm HL Nature, 2015/10/15, Volume 526, Issue 7573, p.336-42, (2015) Read More / View Supplemental Materials
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Identification and characterization of essential genes in the human genome.Wang, T., Birsoy K., Hughes NW, Krupczak KM, Post Y., Wei JJ, Lander E. S., and Sabatini DM Science (New York, N.Y.), 2015/10/15, (2015) Read More / View Supplemental Materials
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Invasive Bladder Cancer: Genomic Insights and Therapeutic Promise.Kim, J., Akbani R., Creighton CJ, Lerner SP, Weinstein J. N., Getz G., and Kwiatkowski DJ Clinical cancer research : an official journal of the American Association for Cancer Research, 2015/10/15, Volume 21, Issue 20, p.4514-24, (2015) Read More / View Supplemental Materials
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Responses to Bacteria, Virus and Malaria Distinguish the Etiology of Pediatric Clinical Pneumonia.Valim, C., Ahmad R., Lanaspa M., Tan Y., Acácio S., Gillette MA, Almendinger KD, Milner DA Jr, Madrid L., Pellé K., Harezlak J., Silterra J., Alonso PL, Carr SA, Mesirov J. P., Wirth DF, Wiegand RC, and Bassat Q. American journal of respiratory and critical care medicine, 2015/10/15, (2015) Read More / View Supplemental Materials
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Reduced Sleep Spindles in Schizophrenia: A Treatable Endophenotype That Links Risk Genes to Impaired Cognition?Manoach, DS, Pan JQ, Purcell SM, and Stickgold R. Biological psychiatry, 2015/10/14, (2015) Read More / View Supplemental Materials
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Common Variants in DRD2 are Associated with Sleep Duration: The CARe Consortium.Cade, BE, Gottlieb DJ, Lauderdale DS, Bennett DA, Buchman AS, Buxbaum SG, De Jager PL, Evans DS, Fülöp T., Gharib SA, Johnson WC, Im HK, Larkin EK, Lee SK, Lim AS, Punjabi NM, Shin C., Stone KL, Tranah GJ, Weng J., et al. Human molecular genetics, 2015/10/13, (2015) Read More / View Supplemental Materials
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Hitting the Target in BRAF-Mutant Colorectal Cancer.Nagaraja, AK, and Bass AJ Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015/10/12, (2015) Read More / View Supplemental Materials
Single-cell ChIP-seq reveals cell subpopulations defined by chromatin state.Rotem, A., Ram O., Shoresh N., Sperling RA, Goren A., Weitz DA, and Bernstein BE Nature biotechnology, 2015/10/12, (2015) Read More / View Supplemental Materials
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Genomic correlates of response to CTLA-4 blockade in metastatic melanoma.Van Allen, EM, Miao D., Schilling B., Shukla SA, Blank C., Zimmer L., Sucker A., Hillen U., Foppen MH, Goldinger SM, Utikal J., Hassel JC, Weide B., Kaehler KC, Loquai C., Mohr P., Gutzmer R., Dummer R., Gabriel S., Wu CJ, et al. Science (New York, N.Y.), 2015/10/09, Volume 350, Issue 6257, p.207-11, (2015) Read More / View Supplemental Materials
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Addressing the burden of mental, neurological, and substance use disorders: key messages from Disease Control Priorities, 3rd edition.Patel, V., Chisholm D., Parikh R., Charlson FJ, Degenhardt L., Dua T., Ferrari AJ, Hyman S., Laxminarayan R., Levin C., Lund C., Medina Mora ME, Petersen I., Scott J., Shidhaye R., Vijayakumar L., Thornicroft G., Whiteford H., and DCP MNS Author Group Lancet (London, England), 2015/10/08, (2015) Read More / View Supplemental Materials
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Comprehensive Molecular Portraits of Invasive Lobular Breast Cancer.Ciriello, G., Gatza ML, Beck AH, Wilkerson MD, Rhie SK, Pastore A., Zhang H., McLellan M., Yau C., Kandoth C., Bowlby R., Shen H., Hayat S., Fieldhouse R., Lester SC, Tse GM, Factor RE, Collins LC, Allison KH, Chen YY, et al. Cell, 2015/10/08, Volume 163, Issue 2, p.506-19, (2015) Read More / View Supplemental Materials
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Sestrin2 is a leucine sensor for the mTORC1 pathway.Wolfson, RL, Chantranupong L., Saxton RA, Shen K., Scaria SM, Cantor JR, and Sabatini DM Science (New York, N.Y.), 2015/10/08, (2015) Read More / View Supplemental Materials
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Evolution of regulatory networks in Candida glabrata: learning to live with the human host.Roy, S., and Thompson D. FEMS yeast research, 2015/10/07, (2015) Read More / View Supplemental Materials
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Identification of and Molecular Basis for SIRT6 Loss-of-Function Point Mutations in Cancer.Kugel, S., Feldman JL, Klein MA, Silberman DM, Sebastián C., Mermel C., Dobersch S., Clark AR, Getz G., Denu JM, and Mostoslavsky R. Cell reports, 2015/10/07, (2015) Read More / View Supplemental Materials
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MitoCarta2.0: an updated inventory of mammalian mitochondrial proteins.Calvo, SE, Clauser KR, and Mootha VK Nucleic acids research, 2015/10/07, (2015) Read More / View Supplemental Materials
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Chromothripsis: A New Mechanism for Rapid Karyotype Evolution.Leibowitz, ML, Zhang CZ, and Pellman D. Annual review of genetics, 2015/10/06, (2015) Read More / View Supplemental Materials
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Comprehensive assessment of cancer missense mutation clustering in protein structures.Kamburov, A., Lawrence MS, Polak P., Leshchiner I., Lage K., Golub T. R., Lander E. S., and Getz G. Proceedings of the National Academy of Sciences of the United States of America, 2015/10/06, Volume 112, Issue 40, p.E5486-95, (2015) Read More / View Supplemental Materials
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Functional, chemical genomic, and super-enhancer screening identify sensitivity to cyclin D1/CDK4 pathway inhibition in Ewing sarcoma.Kennedy, AL, Vallurupalli M., Chen L., Crompton B., Cowley G., Vazquez F., Weir BA, Tsherniak A., Parasuraman S., Kim S., Alexe G., and Stegmaier K. Oncotarget, 2015/10/06, Volume 6, Issue 30, p.30178-93, (2015) Read More / View Supplemental Materials
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Interpreting de novo Variation in Human Disease Using denovolyzeR.Ware, JS, Samocha KE, Homsy J., and Daly M. J. Current protocols in human genetics / editorial board, Jonathan L. Haines ... [et al.], 2015/10/06, Volume 87, p.7.25.1-7.25.15, (2015) Read More / View Supplemental Materials
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Making Biological Sense of GWAS Data: Lessons from the FTO Locus.Herman, MA, and Rosen ED Cell metabolism, 2015/10/06, Volume 22, Issue 4, p.538-9, (2015) Read More / View Supplemental Materials
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Ferritinophagy via NCOA4 is required for erythropoiesis and is regulated by iron dependent HERC2-mediated proteolysis.Mancias, JD, Pontano Vaites L., Nissim S., Biancur DE, Kim AJ, Wang X., Liu Y., Goessling W., Kimmelman AC, and Harper JW eLife, 2015/10/05, Volume 4, (2015) Read More / View Supplemental Materials
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The novel mechanism of lenalidomide activity.Fink, EC, and Ebert BL Blood, 2015/10/05, (2015) Read More / View Supplemental Materials
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Orthogonal gene knockout and activation with a catalytically active Cas9 nuclease.Dahlman, JE, Abudayyeh OO, Joung J., Gootenberg JS, Zhang F., and Konermann S. Nature biotechnology, 2015/10/05, (2015) Read More / View Supplemental Materials
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Population genomic structure and adaptation in the zoonotic malaria parasite Plasmodium knowlesi.Assefa, S., Lim C., Preston MD, Duffy CW, Nair MB, Adroub SA, Kadir KA, Goldberg JM, Neafsey DE, Divis P., Clark TG, Duraisingh MT, Conway DJ, Pain A., and Singh B. Proceedings of the National Academy of Sciences of the United States of America, 2015/10/05, (2015) Read More / View Supplemental Materials
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A respiratory chain controlled signal transduction cascade in the mitochondrial intermembrane space mediates hydrogen peroxide signaling.Patterson, HC, Gerbeth C., Thiru P., Vögtle NF, Knoll M., Shahsafaei A., Samocha KE, Huang CX, Harden MM, Song R., Chen C., Kao J., Shi J., Salmon W., Shaul YD, Stokes MP, Silva JC, Bell GW, Macarthur DG, Ruland J., et al. Proceedings of the National Academy of Sciences of the United States of America, 2015/10/05, (2015) Read More / View Supplemental Materials
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A non-synonymous single-nucleotide polymorphism associated with multiple sclerosis risk affects the EVI5 interactome.Didonna, A., Isobe N., Caillier SJ, Li KH, Burlingame AL, Hauser SL, Baranzini SE, Patsopoulos NA, and Oksenberg JR Human molecular genetics, 2015/10/03, (2015) Read More / View Supplemental Materials
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Whole exome sequencing combined with integrated variant annotation prediction identifies a causative myosin essential light chain variant in hypertrophic cardiomyopathy.Nomura, A., Tada H., Teramoto R., Konno T., Hodatsu A., Won HH, Kathiresan S., Ino H., Fujino N., Yamagishi M., and Hayashi K. Journal of cardiology, 2015/10/03, (2015) Read More / View Supplemental Materials
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Somatic mutation in single human neurons tracks developmental and transcriptional history.Lodato, MA, Woodworth MB, Lee S., Evrony GD, Mehta BK, Karger A., Lee S., Chittenden TW, D'Gama AM, Cai X., Luquette LJ, Lee E., Park PJ, and Walsh CA Science (New York, N.Y.), 2015/10/02, Volume 350, Issue 6256, p.94-8, (2015) Read More / View Supplemental Materials
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CD39 Expression Identifies Terminally Exhausted CD8+ T Cells.Gupta, PK, Godec J., Wolski D., Adland E., Yates K., Pauken KE, Cosgrove C., Ledderose C., Junger WG, Robson SC, Wherry EJ, Alter G., Goulder PJ, Klenerman P., Sharpe AH, Lauer GM, and Haining WN PLoS pathogens, 2015/10/01, Volume 11, Issue 10, p.e1005177, (2015) Read More / View Supplemental Materials
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Concept and design of a genome-wide association genotyping array tailored for transplantation-specific studies.Li, YR, van Setten J., Verma SS, Lu Y., Holmes MV, Gao H., Lek M., Nair N., Chandrupatla H., Chang B., Karczewski KJ, Wong C., Mohebnasab M., Mukhtar E., Phillips R., Tragante V., Hou C., Steel L., Lee T., Garifallou J., et al. Genome medicine, 2015/10/01, Volume 7, Issue 1, p.90, (2015) Read More / View Supplemental Materials
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Disproportionate Contributions of Select Genomic Compartments and Cell Types to Genetic Risk for Coronary Artery Disease.Won, HH, Natarajan P., Dobbyn A., Jordan DM, Roussos P., Lage K., Raychaudhuri S., Stahl E., and Do R. PLoS genetics, 2015/10/01, Volume 11, Issue 10, p.e1005622, (2015) Read More / View Supplemental Materials
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