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2013
Using chromatin marks to interpret and localize genetic associations to complex human traits and diseases.Trynka, G., and Raychaudhuri S. Current opinion in genetics & development, 2013/12/01, Volume 23, Issue 6, p.635-41, (2013) Read More / View Supplemental Materials
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Picking the lock on pluripotency.Eggan, K. The New England journal of medicine, 2013/11/28, Volume 369, Issue 22, p.2150-1, (2013) Read More / View Supplemental Materials
Clinical relevance and functional consequences of the TNFRSF1A multiple sclerosis locus.Ottoboni, L., Frohlich IY, Lee M., Healy BC, Keenan BT, Xia Z., Chitnis T., Guttmann CR, Khoury SJ, Weiner HL, Hafler DA, and De Jager PL Neurology, 2013/11/26, Volume 81, Issue 22, p.1891-9, (2013) Read More / View Supplemental Materials
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Polygenic dissection of diagnosis and clinical dimensions of bipolar disorder and schizophrenia.Ruderfer, DM, Fanous AH, Ripke S., McQuillin A., Amdur RL, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Cross-Disorder Working Group of the Psychiatric Genomics Consortium, Gejman PV, O'Donovan MC, Andreassen OA, Djurovic S., Hultman CM, Kelsoe JR, Jamain S., Landén M., Leboyer M., Nimgaonkar V., Nurnberger J., Smoller JW, et al. Molecular psychiatry, 2013/11/26, (2013) Read More / View Supplemental Materials
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A Small-Molecule Inducer of PDX1 Expression Identified by High-Throughput Screening.Yuan, Y., Hartland K., Boskovic Z., Wang Y., Walpita D., Lysy PA, Zhong C., Young DW, Kim YK, Tolliday NJ, Sokal EM, Schreiber SL, and Wagner BK Chemistry & biology, 2013/11/23, (2013) Read More / View Supplemental Materials
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Shared Genetic Susceptibility to Ischemic Stroke and Coronary Artery Disease: A Genome-Wide Analysis of Common Variants.Dichgans, M., Malik R., König IR, Rosand J., Clarke R., Gretarsdottir S., Thorleifsson G., Mitchell BD, Assimes TL, Levi C., Odonnell CJ, Fornage M., Thorsteinsdottir U., Psaty BM, Hengstenberg C., Seshadri S., Erdmann J., Bis JC, Peters A., Boncoraglio GB, et al. Stroke; a journal of cerebral circulation, 2013/11/21, (2013) Read More / View Supplemental Materials
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DNA Sequencing of Cancer: What Have We Learned?Chmielecki, J., and Meyerson M. Annual review of medicine, 2013/11/20, (2013) Read More / View Supplemental Materials
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A Novel Deletion of IGF1 in a Patient With Idiopathic Short Stature Provides Insight Into IGF1 Haploinsufficiency.Batey, L., Moon JE, Yu Y., Wu B., Hirschhorn JN, Shen Y., and Dauber A. The Journal of clinical endocrinology and metabolism, 2013/11/15, (2013) Read More / View Supplemental Materials
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The plasticity of human Treg and Th17 cells and its role in autoimmunity.Kleinewietfeld, M., and Hafler DA Seminars in immunology, 2013/11/15, Volume 25, Issue 4, p.305-12, (2013) Read More / View Supplemental Materials
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Synthesis and structure-activity relationships of phenyl-substituted coumarins with anti-tubercular activity that target FadD32.Kawate, T., Iwase N., Shimizu M., Stanley SA, Wellington S., Kazyanskaya E., and Hung DT Bioorganic & medicinal chemistry letters, 2013/11/15, Volume 23, Issue 22, p.6052-9, (2013) Read More / View Supplemental Materials
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Modeling disease severity in multiple sclerosis using electronic health records.Xia, Z., Secor E., Chibnik LB, Bove RM, Cheng S., Chitnis T., Cagan A., Gainer VS, Chen PJ, Liao KP, Shaw SY, Ananthakrishnan AN, Szolovits P., Weiner HL, Karlson EW, Murphy SN, Savova GK, Cai T., Churchill SE, Plenge RM, et al. PloS one, 2013/11/11, Volume 8, Issue 11, p.e78927, (2013) Read More / View Supplemental Materials
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SCRIB and PUF60 Are Primary Drivers of the Multisystemic Phenotypes of the 8q24.3 Copy-Number Variant.Dauber, A., Golzio C., Guenot C., Jodelka FM, Kibaek M., Kjaergaard S., Leheup B., Martinet D., Nowaczyk MJ, Rosenfeld JA, Zeesman S., Zunich J., Beckmann JS, Hirschhorn JN, Hastings ML, Jacquemont S., and Katsanis N. American journal of human genetics, 2013/11/07, Volume 93, Issue 5, p.798-811, (2013) Read More / View Supplemental Materials
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MetaRef: a pan-genomic database for comparative and community microbial genomics.Huang, K., Brady A., Mahurkar A., White O., Gevers D., Huttenhower C., and Segata N. Nucleic acids research, 2013/11/06, (2013) Read More / View Supplemental Materials
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A phase II study of the EGFR inhibitor gefitinib in patients with acute myeloid leukemia.DeAngelo, DJ, Neuberg D., Amrein PC, Berchuck J., Wadleigh M., Sirulnik LA, Galinsky I., Golub T., Stegmaier K., and Stone RM Leukemia research, 2013/11/05, (2013) Read More / View Supplemental Materials
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The Aspergillus genome database: multispecies curation and incorporation of RNA-Seq data to improve structural gene annotations.Cerqueira, GC, Arnaud MB, Inglis DO, Skrzypek MS, Binkley G., Simison M., Miyasato SR, Binkley J., Orvis J., Shah P., Wymore F., Sherlock G., and Wortman JR Nucleic acids research, 2013/11/04, (2013) Read More / View Supplemental Materials
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A melanocyte lineage program confers resistance to MAP kinase pathway inhibition.Johannessen, CM, Johnson LA, Piccioni F., Townes A., Frederick DT, Donahue MK, Narayan R., Flaherty KT, Wargo JA, Root DE, and Garraway LA Nature, 2013/11/03, (2013) Read More / View Supplemental Materials
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Apolipoprotein e, statins, and risk of intracerebral hemorrhage.Woo, D., Deka R., Falcone GJ, Flaherty ML, Haverbusch M., Martini SR, Greenberg SM, Ayres AM, Sauerbeck L., Kissela BM, Kleindorfer DO, Moomaw CJ, Anderson CD, Broderick JP, Rosand J., Langefeld CD, and Woo JG Stroke; a journal of cerebral circulation, 2013/11/01, Volume 44, Issue 11, p.3013-7, (2013) Read More / View Supplemental Materials
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Assessing the phenotypic effects in the general population of rare variants in genes for a dominant Mendelian form of diabetes.Flannick, J., Beer NL, Bick AG, Agarwala V., Molnes J., Gupta N., Burtt NP, Florez JC, Meigs JB, Taylor H., Lyssenko V., Irgens H., Fox E., Burslem F., Johansson S., Brosnan MJ, Trimmer JK, Newton-Cheh C., Tuomi T., Molven A., et al. Nature genetics, 2013/11/01, Volume 45, Issue 11, p.1380-5, (2013) Read More / View Supplemental Materials
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Common variants associated with plasma triglycerides and risk for coronary artery disease.Do, R., Willer CJ, Schmidt EM, Sengupta S., Gao C., Peloso GM, Gustafsson S., Kanoni S., Ganna A., Chen J., Buchkovich ML, Mora S., Beckmann JS, Bragg-Gresham JL, Chang HY, Demirkan A., Den Hertog HM, Donnelly LA, Ehret GB, Esko T., et al. Nature genetics, 2013/11/01, Volume 45, Issue 11, p.1345-52, (2013) Read More / View Supplemental Materials
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DSM-5 and RDoC: progress in psychiatry research?Casey, BJ, Craddock N., Cuthbert BN, Hyman SE, Lee FS, and Ressler KJ Nature reviews. Neuroscience, 2013/11/01, Volume 14, Issue 11, p.810-4, (2013) Read More / View Supplemental Materials
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Fine-Mapping the Genetic Association of the Major Histocompatibility Complex in Multiple Sclerosis: HLA and Non-HLA Effects.Patsopoulos, NA, Barcellos LF, Hintzen RQ, Schaefer C., van Duijn CM, Noble JA, Raj T., IMSGC, ANZgene, Gourraud PA, Stranger BE, Oksenberg J., Olsson T., Taylor BV, Sawcer S., Hafler DA, Carrington M., De Jager PL, and de Bakker PI PLoS genetics, 2013/11/01, Volume 9, Issue 11, p.e1003926, (2013) Read More / View Supplemental Materials
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Genome engineering using the CRISPR-Cas9 system.Ran, FA, Hsu PD, Wright J., Agarwala V., Scott DA, and Zhang F. Nature protocols, 2013/11/01, Volume 8, Issue 11, p.2281-308, (2013) Read More / View Supplemental Materials
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Global chromatin profiling reveals NSD2 mutations in pediatric acute lymphoblastic leukemia.Jaffe, JD, Wang Y., Chan HM, Zhang J., Huether R., Kryukov GV, Bhang HE, Taylor JE, Hu M., Englund NP, Yan F., Wang Z., Robert McDonald E 3rd, Wei L., Ma J., Easton J., Yu Z., Debeaumount R., Gibaja V., Venkatesan K., et al. Nature genetics, 2013/11/01, Volume 45, Issue 11, p.1386-91, (2013) Read More / View Supplemental Materials
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Oncogenic mutations in cervical cancer: Genomic differences between adenocarcinomas and squamous cell carcinomas of the cervix.Wright, AA, Howitt BE, Myers AP, Dahlberg SE, Palescandolo E., Van Hummelen P., Macconaill LE, Shoni M., Wagle N., Jones RT, Quick CM, Laury A., Katz IT, Hahn WC, Matulonis UA, and Hirsch MS Cancer, 2013/11/01, Volume 119, Issue 21, p.3776-83, (2013) Read More / View Supplemental Materials
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Progress in the genetics of polygenic brain disorders: significant new challenges for neurobiology.McCarroll, SA, and Hyman SE Neuron, 2013/10/30, Volume 80, Issue 3, p.578-87, (2013) Read More / View Supplemental Materials
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The use of small molecules in somatic-cell reprogramming.Federation, AJ, Bradner JE, and Meissner A. Trends in cell biology, 2013/10/30, (2013) Read More / View Supplemental Materials
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Oncogenic and drug-sensitive NTRK1 rearrangements in lung cancer.Vaishnavi, A., Capelletti M., Le AT, Kako S., Butaney M., Ercan D., Mahale S., Davies KD, Aisner DL, Pilling AB, Berge EM, Kim J., Sasaki H., Park SI, Kryukov G., Garraway LA, Hammerman PS, Haas J., Andrews SW, Lipson D., et al. Nature medicine, 2013/10/27, (2013) Read More / View Supplemental Materials
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Semiconductor-based DNA sequencing of histone modification states.Cheng, CS, Rai K., Garber M., Hollinger A., Robbins D., Anderson S., Macbeth A., Tzou A., Carneiro MO, Raychowdhury R., Russ C., Hacohen N., Gershenwald JE, Lennon N., Nusbaum C., Chin L., Regev A., and Amit I. Nature communications, 2013/10/25, Volume 4, p.2672, (2013) Read More / View Supplemental Materials
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Fast Pairwise IBD Association Testing in Genome-wide Association Studies.Han, B., Kang EY, Raychaudhuri S., de Bakker PI, and Eskin E. Bioinformatics (Oxford, England), 2013/10/24, (2013) Read More / View Supplemental Materials
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Response to 'Predicting the diagnosis of autism spectrum disorder using gene pathway analysis'Robinson, EB, Howrigan D., Yang J., Ripke S., Anttila V., Duncan LE, Jostins L., Barrett JC, Medland SE, Macarthur DG, Breen G., O'Donovan MC, Wray NR, Devlin B., Daly M. J., Visscher PM, Sullivan PF, and Neale BM Molecular psychiatry, 2013/10/22, (2013) Read More / View Supplemental Materials
Evaluating empirical bounds on complex disease genetic architecture.Agarwala, V., Flannick J., Sunyaev S., GoT2D Consortium, and Altshuler D. Nature genetics, 2013/10/20, (2013) Read More / View Supplemental Materials
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Criteria for the use of omics-based predictors in clinical trials.McShane, LM, Cavenagh MM, Lively TG, Eberhard DA, Bigbee WL, Williams PM, Mesirov J. P., Polley MY, Kim KY, Tricoli JV, Taylor JM, Shuman DJ, Simon RM, Doroshow JH, and Conley BA Nature, 2013/10/17, Volume 502, Issue 7471, p.317-20, (2013) Read More / View Supplemental Materials
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Gene signatures related to B-cell proliferation predict influenza vaccine-induced antibody response.Tan, Y., Tamayo P., Nakaya H., Pulendran B., Mesirov J. P., and Haining WN European journal of immunology, 2013/10/17, (2013) Read More / View Supplemental Materials
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Development of transgenic animals for optogenetic manipulation of mammalian nervous system function: progress and prospects for behavioral neuroscience.Ting, JT, and Feng G. Behavioural brain research, 2013/10/15, Volume 255, p.3-18, (2013) Read More / View Supplemental Materials
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Integrative radiogenomic profiling of squamous cell lung cancer.Abazeed, ME, Adams DJ, Hurov KE, Tamayo P., Creighton CJ, Sonkin D., Giacomelli AO, Du C., Fries DF, Wong KK, Mesirov J. P., Loeffler JS, Schreiber SL, Hammerman PS, and Meyerson M. Cancer research, 2013/10/15, Volume 73, Issue 20, p.6289-98, (2013) Read More / View Supplemental Materials
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The somatic genomic landscape of glioblastoma.Brennan, CW, Verhaak RG, McKenna A., Campos B., Noushmehr H., Salama SR, Zheng S., Chakravarty D., Sanborn JZ, Berman SH, Beroukhim R., Bernard B., Wu CJ, Genovese G., Shmulevich I., Barnholtz-Sloan J., Zou L., Vegesna R., Shukla SA, Ciriello G., et al. Cell, 2013/10/10, Volume 155, Issue 2, p.462-77, (2013) Read More / View Supplemental Materials
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Comprehensive identification of mutational cancer driver genes across 12 tumor types.Tamborero, D., Gonzalez-Perez A., Perez-Llamas C., Deu-Pons J., Kandoth C., Reimand J., Lawrence MS, Getz G., Bader GD, Ding L., and Lopez-Bigas N. Scientific reports, 2013/10/02, Volume 3, p.2650, (2013) Read More / View Supplemental Materials
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Advances in inflammatory bowel disease pathogenesis: linking host genetics and the microbiome.Knights, D., Lassen KG, and Xavier RJ Gut, 2013/10/01, Volume 62, Issue 10, p.1505-10, (2013) Read More / View Supplemental Materials
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Calculating statistical power in Mendelian randomization studies.Brion, MJ, Shakhbazov K., and Visscher PM International journal of epidemiology, 2013/10/01, Volume 42, Issue 5, p.1497-501, (2013) Read More / View Supplemental Materials
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A Central Role for mTOR in Lipid Homeostasis.Lamming, DW, and Sabatini DM Cell metabolism, 2013/10/01, Volume 18, Issue 4, p.465-469, (2013) Read More / View Supplemental Materials
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Connecting Genomic Alterations to Cancer Biology with Proteomics: The NCI Clinical Proteomic Tumor Analysis Consortium.Ellis, MJ, Gillette M., Carr SA, Paulovich AG, Smith RD, Rodland KK, Townsend RR, Kinsinger C., Mesri M., Rodriguez H., Liebler DC, and Clinical Proteomic Tumor Analysis Consortium(CPTAC) Cancer discovery, 2013/10/01, Volume 3, Issue 10, p.1108-12, (2013) Read More / View Supplemental Materials
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Genome-wide association analysis identifies 13 new risk loci for schizophrenia.Ripke, S., O'Dushlaine C., Chambert K., Moran JL, Kähler AK, Akterin S., Bergen SE, Collins AL, Crowley JJ, Fromer M., Kim Y., Lee SH, Magnusson PK, Sanchez N., Stahl EA, Williams S., Wray NR, Xia K., Bettella F., Borglum AD, et al. Nature genetics, 2013/10/01, Volume 45, Issue 10, p.1150-9, (2013) Read More / View Supplemental Materials
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Large-scale identification of ubiquitination sites by mass spectrometry.Udeshi, ND, Mertins P., Svinkina T., and Carr SA Nature protocols, 2013/10/01, Volume 8, Issue 10, p.1950-60, (2013) Read More / View Supplemental Materials
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Small molecule inhibitors of zinc-dependent histone deacetylases.Wagner, FF, Weїwer M., Lewis MC, and Holson EB Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2013/10/01, Volume 10, Issue 4, p.589-604, (2013) Read More / View Supplemental Materials
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Stroke Genetics Network (SiGN) Study: Design and Rationale for a Genome-Wide Association Study of Ischemic Stroke Subtypes.Meschia, JF, Arnett DK, Ay H., Brown RD Jr, Benavente OR, Cole JW, de Bakker PI, Dichgans M., Doheny KF, Fornage M., Grewal RP, Gwinn K., Jern C., Conde JJ, Johnson JA, Jood K., Laurie CC, Lee JM, Lindgren A., Markus HS, et al. Stroke; a journal of cerebral circulation, 2013/10/01, Volume 44, Issue 10, p.2694-702, (2013) Read More / View Supplemental Materials
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Activation of the PD-1 pathway contributes to immune escape in EGFR-driven lung tumors.Akbay, EA, Koyama S., Carretero J., Altabef A., Tchaicha JH, Christensen CL, Mikse OR, Cherniack AD, Beauchamp EM, Pugh TJ, Wilkerson MD, Fecci PE, Butaney M., Reibel JB, Soucheray M., Cohoon TJ, Janne PA, Meyerson M., Hayes DN, Shapiro GI, et al. Cancer discovery, 2013/09/27, (2013) Read More / View Supplemental Materials
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The Cancer Genome Atlas Pan-Cancer analysis project.Cancer Genome Atlas Research, Network, Genome Characterization Center, Chang K., Creighton CJ, Davis C., Donehower L., Drummond J., Wheeler D., Ally A., Balasundaram M., Birol I., Butterfield YS, Chu A., Chuah E., Chun HJ, Dhalla N., Guin R., Hirst M., Hirst C., Holt RA, et al. Nature genetics, 2013/09/26, Volume 45, Issue 10, p.1113-20, (2013) Read More / View Supplemental Materials
Exome Sequencing and Directed Clinical Phenotyping Diagnose Cholesterol Ester Storage Disease Presenting as Autosomal Recessive Hypercholesterolemia.Stitziel, NO, Fouchier SW, Sjouke B., Peloso GM, Moscoso AM, Auer PL, Goel A., Gigante B., Barnes TA, Melander O., Orho-Melander M., Duga S., Sivapalaratnam S., Nikpay M., Martinelli N., Girelli D., Jackson RD, Kooperberg C., Lange LA, Ardissino D., et al. Arteriosclerosis, thrombosis, and vascular biology, 2013/09/26, (2013) Read More / View Supplemental Materials
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Pan-cancer patterns of somatic copy number alteration.Zack, TI, Schumacher SE, Carter SL, Cherniack AD, Saksena G., Tabak B., Lawrence MS, Zhang CZ, Wala J., Mermel CH, Sougnez C., Gabriel SB, Hernandez B., Shen H., Laird PW, Getz G., Meyerson M., and Beroukhim R. Nature genetics, 2013/09/26, Volume 45, Issue 10, p.1134-1140, (2013) Read More / View Supplemental Materials
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High reliability in respiratory rate assessment in children with respiratory symptomatology in a rural area in MozambiqueLanaspa, M., Valim C., Acacio S., Almendinger K., Ahmad R., Wiegand R., and Bassat Q. Journal of Tropical Pediatrics, 2013/09/25, (2013) Read More / View Supplemental Materials
Cetuximab response of lung cancer-derived EGF receptor mutants is associated with asymmetric dimerization.Cho, J., Chen L., Sangji N., Okabe T., Yonesaka K., Francis JM, Flavin RJ, Johnson W., Kwon J., Yu S., Greulich HE, Johnson B. E., Eck MJ, Janne PA, Wong KK, and Meyerson M. Cancer research, 2013/09/24, (2013) Read More / View Supplemental Materials
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Distinct pathways regulated by menin and by MLL1 in hematopoietic stem cells and developing B cells.Li, BE, Gan T., Meyerson M., Rabbitts TH, and Ernst P. Blood, 2013/09/19, Volume 122, Issue 12, p.2039-46, (2013) Read More / View Supplemental Materials
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Colorectal Cancers from Distinct Ancestral Populations Show Variations in BRAF Mutation Frequency.Hanna, MC, Go C., Roden C., Jones RT, Pochanard P., Javed AY, Javed A., Mondal C., Palescandolo E., Van Hummelen P., Hatton C., Bass AJ, Chun SM, Na DC, Kim TI, Jang SJ, Osarogiagbon RU, Hahn WC, Meyerson M., Garraway LA, et al. PloS one, 2013/09/16, Volume 8, Issue 9, p.e74950, (2013) Read More / View Supplemental Materials
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Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity.Ran, FA, Hsu PD, Lin CY, Gootenberg JS, Konermann S., Trevino AE, Scott DA, Inoue A., Matoba S., Zhang Y., and Zhang F. Cell, 2013/09/12, Volume 154, Issue 6, p.1380-9, (2013) Read More / View Supplemental Materials
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Protein array-based profiling of CSF identifies RBPJ as an autoantigen in multiple sclerosis.Querol, L., Clark PL, Bailey MA, Cotsapas C., Cross AH, Hafler DA, Kleinstein SH, Lee JY, Yaari G., Willis SN, and O'Connor KC Neurology, 2013/09/10, Volume 81, Issue 11, p.956-963, (2013) Read More / View Supplemental Materials
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Synthesis of piperlogs and analysis of their effects on cells.Boskovic, ZV, Hussain MM, Adams DJ, Dai M., and Schreiber SL Tetrahedron, 2013/09/09, Volume 69, Issue 36, (2013) Read More / View Supplemental Materials
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Locus-specific editing of histone modifications at endogenous enhancers.Mendenhall, EM, Williamson KE, Reyon D., Zou JY, Ram O., Joung JK, and Bernstein BE Nature biotechnology, 2013/09/08, (2013) Read More / View Supplemental Materials
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Genetic evidence for recent population mixture in India.Moorjani, P., Thangaraj K., Patterson N., Lipson M., Loh PR, Govindaraj P., Berger B., Reich D., and Singh L. American journal of human genetics, 2013/09/05, Volume 93, Issue 3, p.422-38, (2013) Read More / View Supplemental Materials
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Mapping the Human Reference Genome's Missing Sequence by Three-Way Admixture in Latino Genomes.Genovese, G., Handsaker RE, Li H., Kenny EE, and McCarroll SA American journal of human genetics, 2013/09/05, Volume 93, Issue 3, p.411-21, (2013) Read More / View Supplemental Materials
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Small-molecule inhibition of inflammatory β-cell death.Lundh, M., Scully SS, Mandrup-Poulsen T., and Wagner BK Diabetes, obesity & metabolism, 2013/09/01, Volume 15 Suppl 3, p.176-84, (2013) Read More / View Supplemental Materials
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Therapeutic potential of isoform selective HDAC inhibitors for the treatment of schizophrenia.Weïwer, M., Lewis MC, Wagner FF, and Holson EB Future medicinal chemistry, 2013/09/01, Volume 5, Issue 13, p.1491-508, (2013) Read More / View Supplemental Materials
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An interactive resource to identify cancer genetic and lineage dependencies targeted by small molecules.Basu, A., Bodycombe NE, Cheah JH, Price EV, Liu K., Schaefer GI, Ebright RY, Stewart ML, Ito D., Wang S., Bracha AL, Liefeld T., Wawer M., Gilbert JC, Wilson AJ, Stransky N., Kryukov GV, Dancik V., Barretina J., Garraway LA, et al. Cell, 2013/08/29, Volume 154, Issue 5, p.1151-61, (2013) Read More / View Supplemental Materials
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An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancers.Roberts, SA, Lawrence MS, Klimczak LJ, Grimm SA, Fargo D., Stojanov P., Kiezun A., Kryukov GV, Carter SL, Saksena G., Harris S., Shah RR, Resnick MA, Getz G., and Gordenin DA Nature genetics, 2013/08/28, Volume 45, Issue 9, p.970-6, (2013) Read More / View Supplemental Materials
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Clonal evolution in hematological malignancies and therapeutic implications.Landau, DA, Carter SL, Getz G., and Wu CJ Leukemia, 2013/08/27, (2013) Read More / View Supplemental Materials
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Charting a dynamic DNA methylation landscape of the human genome.Ziller, MJ, Gu H., Müller F., Donaghey J., Tsai LT, Kohlbacher O., De Jager PL, Rosen ED, Bennett DA, Bernstein BE, Gnirke A., and Meissner A. Nature, 2013/08/22, Volume 500, Issue 7463, p.477-81, (2013) Read More / View Supplemental Materials
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Optical control of mammalian endogenous transcription and epigenetic states.Konermann, S., Brigham MD, Trevino AE, Hsu PD, Heidenreich M., Cong L., Platt RJ, Scott DA, Church GM, and Zhang F. Nature, 2013/08/22, Volume 500, Issue 7463, p.472-6, (2013) Read More / View Supplemental Materials
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Signatures of mutational processes in human cancer.Alexandrov, LB, Nik-Zainal S., Wedge DC, Aparicio SA, Behjati S., Biankin AV, Bignell GR, Bolli N., Borg A., Børresen-Dale AL, Boyault S., Burkhardt B., Butler AP, Caldas C., Davies HR, Desmedt C., Eils R., Eyfjörd JE, Foekens JA, Greaves M., et al. Nature, 2013/08/22, Volume 500, Issue 7463, p.415-21, (2013) Read More / View Supplemental Materials
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Atg16l1 is Required for Autophagy in Intestinal Epithelial Cells and Protection of Mice from Salmonella Infection.Conway, KL, Kuballa P., Song JH, Patel KK, Castoreno AB, Yilmaz OH, Jijon HB, Zhang M., Aldrich LN, Villablanca EJ, Peloquin JM, Goel G., Lee IA, Mizoguchi E., Shi HN, Bhan AK, Shaw SY, Schreiber SL, Virgin HW, Shamji AF, et al. Gastroenterology, 2013/08/21, (2013) Read More / View Supplemental Materials
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Stimulating erythropoiesis in neonates.Sankaran, VG, and Agrawal PB American journal of hematology, 2013/08/20, (2013) Read More / View Supplemental Materials
Gleason Grade Progression Is Uncommon.Penney, KL, Stampfer MJ, Jahn JL, Sinnott JA, Flavin R., Rider JR, Finn S., Giovannucci E., Sesso HD, Loda M., Mucci LA, and Fiorentino M. Cancer research, 2013/08/15, Volume 73, Issue 16, p.5163-5168, (2013) Read More / View Supplemental Materials
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Two-stage microbial community experimental design.Tickle, TL, Segata N., Waldron L., Weingart U., and Huttenhower C. The ISME journal, 2013/08/15, (2013) Read More / View Supplemental Materials
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Fusobacterium nucleatum Potentiates Intestinal Tumorigenesis and Modulates the Tumor-Immune Microenvironment.Kostic, AD, Chun E., Robertson L., Glickman JN, Gallini CA, Michaud M., Clancy TE, Chung DC, Lochhead P., Hold GL, El-Omar EM, Brenner D., Fuchs CS, Meyerson M., and Garrett WS Cell host & microbe, 2013/08/14, Volume 14, Issue 2, p.207-15, (2013) Read More / View Supplemental Materials
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In silico abstraction of zinc finger nuclease cleavage profiles reveals an expanded landscape of off-target sites.Sander, JD, Ramirez CL, Linder SJ, Pattanayak V., Shoresh N., Ku M., Foden JA, Reyon D., Bernstein BE, Liu DR, and Joung JK Nucleic acids research, 2013/08/14, (2013) Read More / View Supplemental Materials
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Identification of Novel Inhibitors of Nonreplicating Mycobacterium tuberculosis Using a Carbon Starvation Model.Grant, SS, Kawate T., Nag PP, Silvis MR, Gordon K., Stanley SA, Kazyanskaya E., Nietupski R., Golas A., FitzGerald M., Cho S., Franzblau SG, and Hung DT ACS chemical biology, 2013/08/13, (2013) Read More / View Supplemental Materials
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Kinannote, a computer program to identify and classify members of the eukaryotic protein kinase superfamily.Goldberg, JM, Griggs AD, Smith JL, Haas BJ, Wortman JR, and Zeng Q. Bioinformatics (Oxford, England), 2013/08/13, (2013) Read More / View Supplemental Materials
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Concordance of gene expression in human protein complexes reveals tissue specificity and pathology.Börnigen, D., Pers TH, Thorrez L., Huttenhower C., Moreau Y., and Brunak S. Nucleic acids research, 2013/08/05, (2013) Read More / View Supplemental Materials
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De novo transcript sequence reconstruction from RNA-seq using the Trinity platform for reference generation and analysis.Haas, BJ, Papanicolaou A., Yassour M., Grabherr M., Blood PD, Bowden J., Couger MB, Eccles D., Li B., Lieber M., Macmanes MD, Ott M., Orvis J., Pochet N., Strozzi F., Weeks N., Westerman R., William T., Dewey CN, Henschel R., et al. Nature protocols, 2013/08/01, Volume 8, Issue 8, p.1494-512, (2013) Read More / View Supplemental Materials
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Identification of small molecules for human hepatocyte expansion and iPS differentiation.Shan, J., Schwartz RE, Ross NT, Logan DJ, Thomas D., Duncan SA, North TE, Goessling W., Carpenter AE, and Bhatia SN Nature chemical biology, 2013/08/01, Volume 9, Issue 8, p.514-20, (2013) Read More / View Supplemental Materials
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Network deconvolution as a general method to distinguish direct dependencies in networks.Feizi, S., Marbach D., Médard M., and Kellis M. Nature biotechnology, 2013/08/01, Volume 31, Issue 8, p.726-33, (2013) Read More / View Supplemental Materials
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Nutrients and growth factors in mTORC1 activation.Efeyan, A., and Sabatini DM Biochemical Society transactions, 2013/08/01, Volume 41, Issue 4, p.902-5, (2013) Read More / View Supplemental Materials
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Validating therapeutic targets through human genetics.Plenge, RM, Scolnick EM, and Altshuler D. Nature reviews. Drug discovery, 2013/08/01, Volume 12, Issue 8, p.581-94, (2013) Read More / View Supplemental Materials
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Mutations in eIF4ENIF1 Are Associated With Primary Ovarian Insufficiency.Kasippillai, T., Macarthur DG, Kirby A., Thomas B., Lambalk CB, Daly M. J., and Welt CK The Journal of clinical endocrinology and metabolism, 2013/07/31, (2013) Read More / View Supplemental Materials
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High-resolution definition of the Vibrio cholerae essential gene set with hidden Markov model-based analyses of transposon-insertion sequencing data.Chao, MC, Pritchard JR, Zhang YJ, Rubin EJ, Livny J., Davis BM, and Waldor MK Nucleic acids research, 2013/07/30, (2013) Read More / View Supplemental Materials
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DNA targeting specificity of RNA-guided Cas9 nucleases.Hsu, PD, Scott DA, Weinstein JA, Ran FA, Konermann S., Agarwala V., Li Y., Fine EJ, Wu X., Shalem O., Cradick TJ, Marraffini LA, Bao G., and Zhang F. Nature biotechnology, 2013/07/21, (2013) Read More / View Supplemental Materials
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Genomics of lymphoid malignancies reveal major activation pathways in lymphocytes.Knoechel, B., and Lohr JG Journal of autoimmunity, 2013/07/20, (2013) Read More / View Supplemental Materials
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Common Variants in CLOCK Are Not Associated with Measures of Sleep Duration in People of European Ancestry from the Sleep Heart Health Study.Lane, JM, Tare A., Cade BE, Chen TH, Punjabi NM, Gottlieb DJ, Scheer FA, Redline S., and Saxena R. Biological psychiatry, 2013/07/17, (2013) Read More / View Supplemental Materials
A Microscale Human Liver Platform that Supports the Hepatic Stages of Plasmodium falciparum and vivax.March, S., Ng S., Velmurugan S., Galstian A., Shan J., Logan DJ, Carpenter AE, Thomas D., Sim BK, Mota MM, Hoffman SL, and Bhatia SN Cell host & microbe, 2013/07/17, Volume 14, Issue 1, p.104-15, (2013) Read More / View Supplemental Materials
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Genetic risk variants in African Americans with multiple sclerosis.Isobe, N., Gourraud PA, Harbo HF, Caillier SJ, Santaniello A., Khankhanian P., Maiers M., Spellman S., Cereb N., Yang S., Pando MJ, Piccio L., Cross AH, De Jager PL, Cree BA, Hauser SL, and Oksenberg JR Neurology, 2013/07/16, Volume 81, Issue 3, p.219-227, (2013) Read More / View Supplemental Materials
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Mutational heterogeneity in cancer and the search for new cancer-associated genes.Lawrence, MS, Stojanov P., Polak P., Kryukov GV, Cibulskis K., Sivachenko A., Carter SL, Stewart C., Mermel CH, Roberts SA, Kiezun A., Hammerman PS, McKenna A., Drier Y., Zou L., Ramos AH, Pugh TJ, Stransky N., Helman E., Kim J., et al. Nature, 2013/07/11, Volume 499, Issue 7457, p.214-8, (2013) Read More / View Supplemental Materials
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The Mycobacterium tuberculosis regulatory network and hypoxia.Galagan, JE, Minch K., Peterson M., Lyubetskaya A., Azizi E., Sweet L., Gomes A., Rustad T., Dolganov G., Glotova I., Abeel T., Mahwinney C., Kennedy AD, Allard R., Brabant W., Krueger A., Jaini S., Honda B., Yu WH, Hickey MJ, et al. Nature, 2013/07/11, Volume 499, Issue 7457, p.178-183, (2013) Read More / View Supplemental Materials
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Diarylcoumarins inhibit mycolic acid biosynthesis and kill Mycobacterium tuberculosis by targeting FadD32.Stanley, SA, Kawate T., Iwase N., Shimizu M., Clatworthy AE, Kazyanskaya E., Sacchettini JC, Ioerger TR, Siddiqi NA, Minami S., Aquadro JA, Schmidt Grant S., Rubin EJ, and Hung DT Proceedings of the National Academy of Sciences of the United States of America, 2013/07/09, Volume 110, Issue 28, p.11565-70, (2013) Read More / View Supplemental Materials
Abstract
Subgroup-Specific Prognostic Implications of TP53 Mutation in Medulloblastoma.Zhukova, N., Ramaswamy V., Remke M., Pfaff E., Shih DJ, Martin DC, Castelo-Branco P., Baskin B., Ray PN, Bouffet E., von Bueren AO, Jones DT, Northcott PA, Kool M., Sturm D., Pugh TJ, Pomeroy SL, Cho YJ, Pietsch T., Gessi M., et al. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013/07/08, (2013) Read More / View Supplemental Materials
Abstract
The Xist lncRNA Exploits Three-Dimensional Genome Architecture to Spread Across the X Chromosome.Engreitz, JM, Pandya-Jones A., McDonel P., Shishkin A., Sirokman K., Surka C., Kadri S., Xing J., Goren A., Lander E. S., Plath K., and Guttman M. Science (New York, N.Y.), 2013/07/04, (2013) Read More / View Supplemental Materials
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Browsing (Epi)genomes: A Guide to Data Resources and Epigenome Browsers for Stem Cell Researchers.Karnik, R., and Meissner A. Cell stem cell, 2013/07/03, Volume 13, Issue 1, p.14-21, (2013) Read More / View Supplemental Materials
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Ribosome Profiling Provides Evidence that Large Noncoding RNAs Do Not Encode Proteins.Guttman, M., Russell P., Ingolia NT, Weissman JS, and Lander E. S. Cell, 2013/07/03, Volume 154, Issue 1, p.240-51, (2013) Read More / View Supplemental Materials
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A Genome-wide Association Study of the Human Metabolome in a Community-Based Cohort.Rhee, EP, Ho JE, Chen MH, Shen D., Cheng S., Larson MG, Ghorbani A., Shi X., Helenius IT, O'Donnell CJ, Souza AL, Deik A., Pierce KA, Bullock K., Walford GA, Vasan RS, Florez JC, Clish C., Yeh JR, Wang TJ, et al. Cell metabolism, 2013/07/02, Volume 18, Issue 1, p.130-43, (2013) Read More / View Supplemental Materials
Abstract
Association Study of Common Genetic Variants and HIV-1 Acquisition in 6,300 Infected Cases and 7,200 Controls.McLaren, PJ, Coulonges C., Ripke S., van den Berg L., Buchbinder S., Carrington M., Cossarizza A., Dalmau J., Deeks SG, Delaneau O., De Luca A., Goedert JJ, Haas D., Herbeck JT, Kathiresan S., Kirk GD, Lambotte O., Luo M., Mallal S., van Manen D., et al. PLoS pathogens, 2013/07/01, Volume 9, Issue 7, p.e1003515, (2013) Read More / View Supplemental Materials
Abstract
CD33 Alzheimer's disease locus: altered monocyte function and amyloid biology.Bradshaw, EM, Chibnik LB, Keenan BT, Ottoboni L., Raj T., Tang A., Rosenkrantz LL, Imboywa S., Lee M., Von Korff A., Alzheimer Disease Neuroimaging Initiative, Morris MC, Evans DA, Johnson K., Sperling RA, Schneider JA, Bennett DA, and De Jager PL Nature neuroscience, 2013/07/01, Volume 16, Issue 7, p.848-50, (2013) Read More / View Supplemental Materials
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Comparative genomics as a tool to understand evolution and disease.Alföldi, J., and Lindblad-Toh K. Genome research, 2013/07/01, Volume 23, Issue 7, p.1063-8, (2013) Read More / View Supplemental Materials
Abstract
Integrated proteomic analysis of post-translational modifications by serial enrichment.Mertins, P., Qiao JW, Patel J., Udeshi ND, Clauser KR, Mani D. R., Burgess MW, Gillette MA, Jaffe JD, and Carr SA Nature methods, 2013/07/01, Volume 10, Issue 7, p.634-7, (2013) Read More / View Supplemental Materials
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