Publications

Shared components of heritability across genetically correlated traits.

Ballard JLee, O'Connor LJen. Shared components of heritability across genetically correlated traits. Am J Hum Genet. 2022. doi:10.1016/j.ajhg.2022.04.003.

Somatic genomic changes in single Alzheimer's disease neurons.

Miller MB, Huang AYue, Kim J, et al. Somatic genomic changes in single Alzheimer's disease neurons. Nature. 2022. doi:10.1038/s41586-022-04640-1.

Simple, fast, and flexible framework for matrix completion with infinite width neural networks.

Radhakrishnan A, Stefanakis G, Belkin M, Uhler C. Simple, fast, and flexible framework for matrix completion with infinite width neural networks. Proc Natl Acad Sci U S A. 2022;119(16):e2115064119. doi:10.1073/pnas.2115064119.

Phenotypic Screening for Small Molecules that Protect β-Cells from Glucolipotoxicity.

Small JC, Joblin-Mills A, Carbone K, et al. Phenotypic Screening for Small Molecules that Protect β-Cells from Glucolipotoxicity. ACS Chem Biol. 2022. doi:10.1021/acschembio.2c00052.

Phosphate dysregulation via the XPR1-KIDINS220 protein complex is a therapeutic vulnerability in ovarian cancer.

Bondeson DP, Paolella BR, Asfaw A, et al. Phosphate dysregulation via the XPR1-KIDINS220 protein complex is a therapeutic vulnerability in ovarian cancer. Nat Cancer. 2022. doi:10.1038/s43018-022-00360-7.

Getting genetic ancestry right for science and society.

Lewis ACF, Molina SJ, Appelbaum PS, et al. Getting genetic ancestry right for science and society. Science. 2022;376(6590):250-252. doi:10.1126/science.abm7530.

Dynamics of CTCF- and cohesin-mediated chromatin looping revealed by live-cell imaging.

Gabriele M, Brandão HB, Grosse-Holz S, et al. Dynamics of CTCF- and cohesin-mediated chromatin looping revealed by live-cell imaging. Science. 2022:eabn6583. doi:10.1126/science.abn6583.

A single-cell liver atlas of Plasmodium vivax infection.

Mancio-Silva L, Gural N, Real E, et al. A single-cell liver atlas of Plasmodium vivax infection. Cell Host Microbe. 2022. doi:10.1016/j.chom.2022.03.034.

Cellular and transcriptional diversity over the course of human lactation.

Nyquist SK, Gao P, Haining TKJ, et al. Cellular and transcriptional diversity over the course of human lactation. Proc Natl Acad Sci U S A. 2022;119(15):e2121720119. doi:10.1073/pnas.2121720119.

A screen of repurposed drugs identifies AMHR2/MISR2 agonists as potential contraceptives.

Li YI, Wei L, Meinsohn M-C, et al. A screen of repurposed drugs identifies AMHR2/MISR2 agonists as potential contraceptives. Proc Natl Acad Sci U S A. 2022;119(15):e2122512119. doi:10.1073/pnas.2122512119.