Publications

Compressing gene expression data using multiple latent space dimensionalities learns complementary biological representations.

Way GP, Zietz M, Rubinetti V, Himmelstein DS, Greene CS. Compressing gene expression data using multiple latent space dimensionalities learns complementary biological representations. Genome Biol. 2020;21(1):109. doi:10.1186/s13059-020-02021-3.

Comprehensive Analysis of Genetic Ancestry and Its Molecular Correlates in Cancer.

Carrot-Zhang J, Chambwe N, Damrauer JS, et al. Comprehensive Analysis of Genetic Ancestry and Its Molecular Correlates in Cancer. Cancer Cell. 2020;37(5):639-654.e6. doi:10.1016/j.ccell.2020.04.012.

The Glioma Stem Cell Model in the Era of Single-Cell Genomics.

Suvà ML, Tirosh I. The Glioma Stem Cell Model in the Era of Single-Cell Genomics. Cancer Cell. 2020;37(5):630-636. doi:10.1016/j.ccell.2020.04.001.

Comparison of Proteomic Assessment Methods in Multiple Cohort Studies.

Raffield LM, Dang H, Pratte KA, et al. Comparison of Proteomic Assessment Methods in Multiple Cohort Studies. Proteomics. 2020:e1900278. doi:10.1002/pmic.201900278.

Annotations capturing cell type-specific TF binding explain a large fraction of disease heritability.

van de Geijn B, Finucane H, Gazal S, et al. Annotations capturing cell type-specific TF binding explain a large fraction of disease heritability. Hum Mol Genet. 2020;29(7):1057-1067. doi:10.1093/hmg/ddz226.

Successful treatment of intractable epilepsy with ketogenic diet therapy in twins with ALG3-CDG.

Paketci C, Edem P, Hiz S, et al. Successful treatment of intractable epilepsy with ketogenic diet therapy in twins with ALG3-CDG. Brain Dev. 2020. doi:10.1016/j.braindev.2020.04.008.

Analysis of cardiac magnetic resonance imaging in 36,000 individuals yields genetic insights into dilated cardiomyopathy.

Pirruccello JP, Bick A, Wang M, et al. Analysis of cardiac magnetic resonance imaging in 36,000 individuals yields genetic insights into dilated cardiomyopathy. Nat Commun. 2020;11(1):2254. doi:10.1038/s41467-020-15823-7.

MR Imaging Correlates for Molecular and Mutational Analyses in Children with Diffuse Intrinsic Pontine Glioma.

Jaimes C, Vajapeyam S, Brown D, et al. MR Imaging Correlates for Molecular and Mutational Analyses in Children with Diffuse Intrinsic Pontine Glioma. AJNR Am J Neuroradiol. 2020. doi:10.3174/ajnr.A6546.

A human lung tumor microenvironment interactome identifies clinically relevant cell-type cross-talk.

Gentles AJ, Hui ABik-Yu, Feng W, et al. A human lung tumor microenvironment interactome identifies clinically relevant cell-type cross-talk. Genome Biol. 2020;21(1):107. doi:10.1186/s13059-020-02019-x.

Evaluating the impact of trauma and PTSD on epigenetic prediction of lifespan and neural integrity.

Katrinli S, Stevens J, Wani AH, et al. Evaluating the impact of trauma and PTSD on epigenetic prediction of lifespan and neural integrity. Neuropsychopharmacology. 2020. doi:10.1038/s41386-020-0700-5.