Publications

A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk.

Manning A, Highland HM, Gasser J, et al. A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk. Diabetes. 2017;66(7):2019-2032. doi:10.2337/db16-1329.

Behavioral, transcriptomic and epigenetic responses to social challenge in honey bees.

Shpigler HY, Saul MC, Murdoch EE, et al. Behavioral, transcriptomic and epigenetic responses to social challenge in honey bees. Genes Brain Behav. 2017;16(6):579-591. doi:10.1111/gbb.12379.

Exploring the relationship between α-actinin-3 deficiency and obesity in mice and humans.

Houweling PJ, Berman YD, Turner N, et al. Exploring the relationship between α-actinin-3 deficiency and obesity in mice and humans. Int J Obes (Lond). 2017;41(7):1154-1157. doi:10.1038/ijo.2017.72.

Type 2 Diabetes Variants Disrupt Function of SLC16A11 through Two Distinct Mechanisms.

Rusu V, Hoch E, Mercader JM, et al. Type 2 Diabetes Variants Disrupt Function of SLC16A11 through Two Distinct Mechanisms. Cell. 2017;170(1):199-212.e20. doi:10.1016/j.cell.2017.06.011.

Scaffold Diversity from N-Acyliminium Ions.

Wu P, Nielsen TE. Scaffold Diversity from N-Acyliminium Ions. Chem Rev. 2017;117(12):7811-7856. doi:10.1021/acs.chemrev.6b00806.

Rare germline variants in ATM are associated with chronic lymphocytic leukemia.

Tiao G, Improgo MR, Kasar S, et al. Rare germline variants in ATM are associated with chronic lymphocytic leukemia. Leukemia. 2017. doi:10.1038/leu.2017.201.

Protein-Truncating Variants at the Cholesteryl Ester Transfer Protein Gene and Risk for Coronary Heart Disease.

Nomura A, Won H-H, Khera AV, et al. Protein-Truncating Variants at the Cholesteryl Ester Transfer Protein Gene and Risk for Coronary Heart Disease. Circ Res. 2017;121(1):81-88. doi:10.1161/CIRCRESAHA.117.311145.

CRISPR-Cas9 Mediated DNA Unwinding Detected Using Site-Directed Spin Labeling.

Tangprasertchai NS, Di Felice R, Zhang X, et al. CRISPR-Cas9 Mediated DNA Unwinding Detected Using Site-Directed Spin Labeling. ACS Chem Biol. 2017;12(6):1489-1493. doi:10.1021/acschembio.6b01137.

Discovery of novel heart rate-associated loci using the Exome Chip.

Van Den Berg ME, Warren HR, Cabrera CP, et al. Discovery of novel heart rate-associated loci using the Exome Chip. Hum Mol Genet. 2017;26(12):2346-2363. doi:10.1093/hmg/ddx113.

Mendelian randomisation implicates hyperlipidaemia as a risk factor for colorectal cancer.

Rodriguez-Broadbent H, Law PJ, Sud A, et al. Mendelian randomisation implicates hyperlipidaemia as a risk factor for colorectal cancer. Int J Cancer. 2017;140(12):2701-2708. doi:10.1002/ijc.30709.