Publications

Proteogenomic insights into the biology and treatment of HPV-negative head and neck squamous cell carcinoma.

Huang C, Chen L, Savage SR, et al. Proteogenomic insights into the biology and treatment of HPV-negative head and neck squamous cell carcinoma. Cancer Cell. 2021. doi:10.1016/j.ccell.2020.12.007.

CBL mutations drive PI3K/AKT signaling via increased interaction with LYN and PIK3R1.

Belizaire R, Koochaki SHassan Joh, Udeshi ND, et al. CBL mutations drive PI3K/AKT signaling via increased interaction with LYN and PIK3R1. Blood. 2021. doi:10.1182/blood.2020006528.

Creating a Framework to Integrate Residency Program and Medical Center Approaches to Quality Improvement and Patient Safety Training.

Chen A, Wolpaw BJ, Vusse LKVande, et al. Creating a Framework to Integrate Residency Program and Medical Center Approaches to Quality Improvement and Patient Safety Training. Acad Med. 2021;96(1):75-82. doi:10.1097/ACM.0000000000003725.

The conserved translation factor LepA is required for optimal synthesis of a porin family in .

Fishbein SRS, Tomasi FG, Wolf ID, et al. The conserved translation factor LepA is required for optimal synthesis of a porin family in . J Bacteriol. 2020. doi:10.1128/JB.00604-20.

Cohesin mutations alter DNA damage repair and chromatin structure and create therapeutic vulnerabilities in MDS/AML.

Tothova Z, Valton A-L, Gorelov R, et al. Cohesin mutations alter DNA damage repair and chromatin structure and create therapeutic vulnerabilities in MDS/AML. JCI Insight. 2020. doi:10.1172/jci.insight.142149.

The SARS-CoV-2 RNA-protein interactome in infected human cells.

Schmidt N, Lareau CA, Keshishian H, et al. The SARS-CoV-2 RNA-protein interactome in infected human cells. Nat Microbiol. 2020. doi:10.1038/s41564-020-00846-z.

Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q.

Neggers JE, Paolella BR, Asfaw A, et al. Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q. Cell Rep. 2020;33(11):108493. doi:10.1016/j.celrep.2020.108493.

Phylogenetic analysis of SARS-CoV-2 in Boston highlights the impact of superspreading events.

Lemieux JE, Siddle KJ, Shaw BM, et al. Phylogenetic analysis of SARS-CoV-2 in Boston highlights the impact of superspreading events. Science. 2020. doi:10.1126/science.abe3261.

A validated lineage-derived somatic truth data set enables benchmarking in cancer genome analysis.

Shand M, Soto J, Lichtenstein L, et al. A validated lineage-derived somatic truth data set enables benchmarking in cancer genome analysis. Commun Biol. 2020;3(1):744. doi:10.1038/s42003-020-01460-9.

BICRA, a SWI/SNF Complex Member, Is Associated with BAF-Disorder Related Phenotypes in Humans and Model Organisms.

Barish S, Barakat TStefan, Michel BC, et al. BICRA, a SWI/SNF Complex Member, Is Associated with BAF-Disorder Related Phenotypes in Humans and Model Organisms. Am J Hum Genet. 2020;107(6):1096-1112. doi:10.1016/j.ajhg.2020.11.003.