Ence CC, Uddin T, Borrel J, et al. Bicyclic pyrrolidine inhibitors of phenylalanine t-RNA synthetase with antiparasitic potency and brain exposure. bioRxiv : the preprint server for biology. 2024. doi:10.1101/2024.02.28.582607Google ScholarDOIPubMed
Publications
Strausz S, Abner E, Blacker G, et al. SCGB1D2 inhibits growth of Borrelia burgdorferi and affects susceptibility to Lyme disease. Nature communications. 2024;15(1):2041. doi:10.1038/s41467-024-45983-9Google ScholarDOIPubMed
Zañudo JGT, Barroso-Sousa R, Jain E, et al. Exemestane plus everolimus and palbociclib in metastatic breast cancer: clinical response and genomic/transcriptomic determinants of resistance in a phase I/II trial. Nature communications. 2024;15(1):2446. doi:10.1038/s41467-024-45835-6Google ScholarDOIPubMed
Chen JH, Nieman LT, Spurrell M, et al. Human lung cancer harbors spatially organized stem-immunity hubs associated with response to immunotherapy. Nature immunology. 2024. doi:10.1038/s41590-024-01792-2Google ScholarDOIPubMed
Lu MY, Chen B, Williamson DFK, et al. A visual-language foundation model for computational pathology. Nature medicine. 2024. doi:10.1038/s41591-024-02856-4DOIGoogle ScholarPubMed
Chen RJ, Ding T, Lu MY, et al. Towards a general-purpose foundation model for computational pathology. Nature medicine. 2024. doi:10.1038/s41591-024-02857-3DOIGoogle ScholarPubMed
Yao D, Tycko J, Oh JW, et al. Multicenter integrated analysis of noncoding CRISPRi screens. Nature methods. 2024. doi:10.1038/s41592-024-02216-7DOIGoogle ScholarPubMed
Kreeger LJ, Honnuraiah S, Maeker S, Shea S, Fishell G, Goodrich L V. An Anatomical and Physiological Basis for Coincidence Detection Across Time Scales in the Auditory System. bioRxiv : the preprint server for biology. 2024. doi:10.1101/2024.02.29.582808DOIGoogle ScholarPubMed
Jackson RJ, Keiser MS, Meltzer JC, et al. APOE2 gene therapy reduces amyloid deposition, and improves markers of neuroinflammation and neurodegeneration in a mouse model of Alzheimer disease. Molecular therapy : the journal of the American Society of Gene Therapy. 2024. doi:10.1016/j.ymthe.2024.03.024Google ScholarDOIPubMed
Kerola AM, Palomäki A, Laivuori H, et al. Patterns of reproductive health in inflammatory rheumatic diseases and other immune-mediated diseases: a nationwide registry study. Rheumatology (Oxford, England). 2024. doi:10.1093/rheumatology/keae122Google ScholarDOIPubMed