Mono- and biallelic variant effects on disease at biobank scale. Nature. 2023. doi:10.1038/s41586-022-05420-7.DOIGoogle ScholarPubMed
Publications
FinnGen provides genetic insights from a well-phenotyped isolated population. Nature. 2023. doi:10.1038/s41586-022-05473-8.DOIGoogle ScholarPubMed
Cervia LD, Shibue T, Borah AA, et al. A ubiquitination cascade regulating the integrated stress response and survival in carcinomas. Cancer Discov. 2022. doi:10.1158/2159-8290.CD-22-1230.DOIGoogle ScholarPubMed
Weingarten-Gabbay S, Pearlman LR, Chen D-Y, et al. HLA-I immunopeptidome profiling of human cells infected with high-containment enveloped viruses. STAR Protoc. 2022;3(4):101910. doi:10.1016/j.xpro.2022.101910.DOIGoogle ScholarPubMed
Shuster A, Li J, Chon UR, et al. In situ cell-type-specific cell-surface proteomic profiling in mice. Neuron. 2022;110(23):3882-3896.e9. doi:10.1016/j.neuron.2022.09.025.DOIGoogle ScholarPubMed
Jutzi JS, Marneth AE, Jiménez-Santos MJ, et al. CALR-mutated cells are vulnerable to combined inhibition of the proteasome and the endoplasmic reticulum stress response. Leukemia. 2022. doi:10.1038/s41375-022-01781-0.DOIGoogle ScholarPubMed
Ghosh S, Nehme R, Barrett LE. Greater genetic diversity is needed in human pluripotent stem cell models. Nat Commun. 2022;13(1):7301. doi:10.1038/s41467-022-34940-z.DOIGoogle ScholarPubMed
Boiarsky R, Haradhvala NJ, Alberge J-B, et al. Single cell characterization of myeloma and its precursor conditions reveals transcriptional signatures of early tumorigenesis. Nat Commun. 2022;13(1):7040. doi:10.1038/s41467-022-33944-z.DOIGoogle ScholarPubMed
Lim D, Zhou Q, Cox KJ, et al. A general approach to identify cell-permeable and synthetic anti-CRISPR small molecules. Nat Cell Biol. 2022. doi:10.1038/s41556-022-01005-8.DOIGoogle ScholarPubMed
Stanton AC, Lagerborg KA, Tellez L, et al. Systemic administration of novel engineered AAV capsids facilitates enhanced transgene expression in the macaque CNS. Med (N Y). 2022. doi:10.1016/j.medj.2022.11.002.DOIGoogle ScholarPubMed