Publications
Disease stages and therapeutic hypotheses in two decades of neurodegenerative disease clinical trials. Sci Rep. 2022;12(1):17708. doi:10.1038/s41598-022-21820-1. .
Transcriptional and functional consequences of alterations to MEF2C and its topological organization in neuronal models. Am J Hum Genet. 2022. doi:10.1016/j.ajhg.2022.09.015.
Structure of the OMEGA nickase IsrB in complex with ωRNA and target DNA. Nature. 2022. doi:10.1038/s41586-022-05324-6.
A saturated map of common genetic variants associated with human height. Nature. 2022. doi:10.1038/s41586-022-05275-y.
Spatial maps of T cell receptors and transcriptomes reveal distinct immune niches and interactions in the adaptive immune response. Immunity. 2022;55(10):1940-1952.e5. doi:10.1016/j.immuni.2022.09.002.
The diverse genetic origins of a Classical period Greek army. Proc Natl Acad Sci U S A. 2022;119(41):e2205272119. doi:10.1073/pnas.2205272119.
Single-cell dissection of the obesity-exercise axis in adipose-muscle tissues implies a critical role for mesenchymal stem cells. Cell Metab. 2022;34(10):1578-1593.e6. doi:10.1016/j.cmet.2022.09.004.
Multiscale profiling of protease activity in cancer. Nat Commun. 2022;13(1):5745. doi:10.1038/s41467-022-32988-5.
In vivo CRISPR screens reveal the landscape of immune evasion pathways across cancer. Nat Immunol. 2022;23(10):1495-1506. doi:10.1038/s41590-022-01315-x.
Long-range phasing of dynamic, tissue-specific and allele-specific regulatory elements. Nat Genet. 2022;54(10):1504-1513. doi:10.1038/s41588-022-01188-8.