Publications

Integrated molecular drivers coordinate biological and clinical states in melanoma.

Conway JR, Dietlein F, Taylor-Weiner A, et al. Integrated molecular drivers coordinate biological and clinical states in melanoma. Nat Genet. 2020;52(12):1373-1383. doi:10.1038/s41588-020-00739-1.

Small-molecule-induced polymerization triggers degradation of BCL6.

Słabicki M, Yoon H, Koeppel J, et al. Small-molecule-induced polymerization triggers degradation of BCL6. Nature. 2020;588(7836):164-168. doi:10.1038/s41586-020-2925-1.

A metastasis map of human cancer cell lines.

Jin X, Demere Z, Nair K, et al. A metastasis map of human cancer cell lines. Nature. 2020;588(7837):331-336. doi:10.1038/s41586-020-2969-2.

Quantification of aneuploidy in targeted sequencing data using ASCETS.

Spurr LF, Touat M, Taylor AM, et al. Quantification of aneuploidy in targeted sequencing data using ASCETS. Bioinformatics. 2020. doi:10.1093/bioinformatics/btaa980.

In vivo Perturb-Seq reveals neuronal and glial abnormalities associated with autism risk genes.

Jin X, Simmons SK, Guo A, et al. In vivo Perturb-Seq reveals neuronal and glial abnormalities associated with autism risk genes. Science. 2020;370(6520). doi:10.1126/science.aaz6063.

Tolerogenic nanoparticles suppress central nervous system inflammation.

Kenison JE, Jhaveri A, Li Z, et al. Tolerogenic nanoparticles suppress central nervous system inflammation. Proc Natl Acad Sci U S A. 2020. doi:10.1073/pnas.2016451117.

Single-Cell Profiling of Ebola Virus Disease In Vivo Reveals Viral and Host Dynamics.

Kotliar D, Lin AE, Logue J, et al. Single-Cell Profiling of Ebola Virus Disease In Vivo Reveals Viral and Host Dynamics. Cell. 2020;183(5):1383-1401.e19. doi:10.1016/j.cell.2020.10.002.

Proteogenomic Landscape of Breast Cancer Tumorigenesis and Targeted Therapy.

Krug K, Jaehnig EJ, Satpathy S, et al. Proteogenomic Landscape of Breast Cancer Tumorigenesis and Targeted Therapy. Cell. 2020;183(5):1436-1456.e31. doi:10.1016/j.cell.2020.10.036.

Comprehensive Mapping of Key Regulatory Networks that Drive Oncogene Expression.

Lin L, Holmes B, Shen MW, et al. Comprehensive Mapping of Key Regulatory Networks that Drive Oncogene Expression. Cell Rep. 2020;33(8):108426. doi:10.1016/j.celrep.2020.108426.

CloneSifter: enrichment of rare clones from heterogeneous cell populations.

Feldman D, Tsai FN, Garrity AJ, et al. CloneSifter: enrichment of rare clones from heterogeneous cell populations. BMC Biol. 2020;18(1):177. doi:10.1186/s12915-020-00911-3.