Publications
Rare coding variants in ten genes confer substantial risk for schizophrenia. Nature. 2022;604(7906):509-516. doi:10.1038/s41586-022-04556-w.
TAILS Identifies Candidate Substrates and Biomarkers of ADAMTS7, a Therapeutic Protease Target in Coronary Artery Disease. Mol Cell Proteomics. 2022;21(4):100223. doi:10.1016/j.mcpro.2022.100223.
CRISPR activation screen identifies BCL-2 proteins and B3GNT2 as drivers of cancer resistance to T cell-mediated cytotoxicity. Nat Commun. 2022;13(1):1606. doi:10.1038/s41467-022-29205-8.
Prevalence of monoclonal gammopathies and clinical outcomes in a high-risk US population screened by mass spectrometry: a multicentre cohort study. Lancet Haematol. 2022. doi:10.1016/S2352-3026(22)00069-2.
HLA autoimmune risk alleles restrict the hypervariable region of T cell receptors. Nat Genet. 2022. doi:10.1038/s41588-022-01032-z. .
Systematic identification of biomarker-driven drug combinations to overcome resistance. Nat Chem Biol. 2022. doi:10.1038/s41589-022-00996-7.
Hepatic IRF3 fuels dysglycemia in obesity through direct regulation of Ppp2r1b. Sci Transl Med. 2022;14(637):eabh3831. doi:10.1126/scitranslmed.abh3831.
Multiplexed action-outcome representation by striatal striosome-matrix compartments detected with a mouse cost-benefit foraging task. Nat Commun. 2022;13(1):1541. doi:10.1038/s41467-022-28983-5.
Screening for modulators of the cellular composition of gut epithelia via organoid models of intestinal stem cell differentiation. Nat Biomed Eng. 2022. doi:10.1038/s41551-022-00863-9.
A non-dividing cell population with high pyruvate dehydrogenase kinase activity regulates metabolic heterogeneity and tumorigenesis in the intestine. Nat Commun. 2022;13(1):1503. doi:10.1038/s41467-022-29085-y.