Publications

Optical Pooled Screens in Human Cells.

Feldman D, Singh A, Schmid-Burgk JL, et al. Optical Pooled Screens in Human Cells. Cell. 2019;179(3):787-799.e17. doi:10.1016/j.cell.2019.09.016.

Genome-wide Association Studies in Ancestrally Diverse Populations: Opportunities, Methods, Pitfalls, and Recommendations.

Peterson RE, Kuchenbaecker K, Walters RK, et al. Genome-wide Association Studies in Ancestrally Diverse Populations: Opportunities, Methods, Pitfalls, and Recommendations. Cell. 2019;179(3):589-603. doi:10.1016/j.cell.2019.08.051.

Altered chromosomal topology drives oncogenic programs in SDH-deficient GIST.

Flavahan WA, Drier Y, Johnstone SE, et al. Altered chromosomal topology drives oncogenic programs in SDH-deficient GIST. Nature. 2019. doi:10.1038/s41586-019-1668-3.

International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci.

Nievergelt CM, Maihofer AX, Klengel T, et al. International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci. Nat Commun. 2019;10(1):4558. doi:10.1038/s41467-019-12576-w.

Programmable Inhibition and Detection of RNA Viruses Using Cas13.

Freije CA, Myhrvold C, Boehm CK, et al. Programmable Inhibition and Detection of RNA Viruses Using Cas13. Mol Cell. 2019. doi:10.1016/j.molcel.2019.09.013.

Synthetic Lethal Interaction of SHOC2 Depletion with MEK Inhibition in RAS-Driven Cancers.

Sulahian R, Kwon JJ, Walsh KH, et al. Synthetic Lethal Interaction of SHOC2 Depletion with MEK Inhibition in RAS-Driven Cancers. Cell Rep. 2019;29(1):118-134.e8. doi:10.1016/j.celrep.2019.08.090.

Multiplexed and high-throughput neuronal fluorescence imaging with diffusible probes.

Guo S-M, Veneziano R, Gordonov S, et al. Multiplexed and high-throughput neuronal fluorescence imaging with diffusible probes. Nat Commun. 2019;10(1):4377. doi:10.1038/s41467-019-12372-6.

Metabolomic adaptations and correlates of survival to immune checkpoint blockade.

Li H, Bullock K, Gurjao C, et al. Metabolomic adaptations and correlates of survival to immune checkpoint blockade. Nat Commun. 2019;10(1):4346. doi:10.1038/s41467-019-12361-9.

Genome-Wide Association Study of Diabetic Kidney Disease Highlights Biology Involved in Glomerular Basement Membrane Collagen.

Salem RM, Todd JN, Sandholm N, et al. Genome-Wide Association Study of Diabetic Kidney Disease Highlights Biology Involved in Glomerular Basement Membrane Collagen. J Am Soc Nephrol. 2019. doi:10.1681/ASN.2019030218.

Discovery of high-confidence human protein-coding genes and exons by whole-genome PhyloCSF helps elucidate 118 GWAS loci.

Mudge JM, Jungreis I, Hunt T, et al. Discovery of high-confidence human protein-coding genes and exons by whole-genome PhyloCSF helps elucidate 118 GWAS loci. Genome Res. 2019. doi:10.1101/gr.246462.118.