Publications

BMI-adjusted adipose tissue volumes exhibit depot-specific and divergent associations with cardiometabolic diseases.

Agrawal S, Klarqvist M, Diamant N, et al. BMI-adjusted adipose tissue volumes exhibit depot-specific and divergent associations with cardiometabolic diseases. Nature communications. 2023;14(1):266. doi:10.1038/s41467-022-35704-5.DOI Google Scholar PubMed

The ETS transcription factor ETV6 constrains the transcriptional activity of EWS-FLI to promote Ewing sarcoma.

Lu D, Ellegast J, Ross K, et al. The ETS transcription factor ETV6 constrains the transcriptional activity of EWS-FLI to promote Ewing sarcoma. Nature cell biology. 2023. doi:10.1038/s41556-022-01059-8.DOI Google Scholar PubMed

Astrocytic cell adhesion genes linked to schizophrenia correlate with synaptic programs in neurons.

Pietiläinen O, Trehan A, Meyer D, et al. Astrocytic cell adhesion genes linked to schizophrenia correlate with synaptic programs in neurons. Cell reports. 2023;42(1):111988. doi:10.1016/j.celrep.2022.111988.DOI Google Scholar PubMed

Combined PD-1, BRAF and MEK inhibition in BRAF colorectal cancer: a phase 2 trial.

Tian J. Combined PD-1, BRAF and MEK inhibition in BRAF colorectal cancer: a phase 2 trial. Nature medicine. 2023. doi:10.1038/s41591-022-02181-8.DOI Google Scholar PubMed

Integrative in situ mapping of single-cell transcriptional states and tissue histopathology in a mouse model of Alzheimer's disease.

Zeng H, Huang J, Zhou H, et al. Integrative in situ mapping of single-cell transcriptional states and tissue histopathology in a mouse model of Alzheimer's disease. Nature neuroscience. 2023. doi:10.1038/s41593-022-01251-x.DOI Google Scholar PubMed

The landscape of immune dysregulation in Crohn's disease revealed through single-cell transcriptomic profiling in the ileum and colon.

Kong L, Pokatayev V, Lefkovith A, et al. The landscape of immune dysregulation in Crohn's disease revealed through single-cell transcriptomic profiling in the ileum and colon. Immunity. 2023. doi:10.1016/j.immuni.2023.01.002.DOI Google Scholar PubMed

Targeting TBK1 to overcome resistance to cancer immunotherapy.

Sun Y, Revach O-Y, Anderson S, et al. Targeting TBK1 to overcome resistance to cancer immunotherapy. Nature. 2023. doi:10.1038/s41586-023-05704-6.DOI Google Scholar PubMed

Mono- and biallelic variant effects on disease at biobank scale

Mono- and biallelic variant effects on disease at biobank scale. Nature. 2023. doi:10.1038/s41586-022-05420-7.DOI Google Scholar PubMed

FinnGen provides genetic insights from a well-phenotyped isolated population

FinnGen provides genetic insights from a well-phenotyped isolated population. Nature. 2023. doi:10.1038/s41586-022-05473-8.DOI Google Scholar PubMed

A ubiquitination cascade regulating the integrated stress response and survival in carcinomas.

Cervia LD, Shibue T, Borah AA, et al. A ubiquitination cascade regulating the integrated stress response and survival in carcinomas. Cancer Discov. 2022. doi:10.1158/2159-8290.CD-22-1230.DOI Google Scholar PubMed