Publications
Prioritization of autoimmune disease-associated genetic variants that perturb regulatory element activity in T cells. Nat Genet. 2022. doi:10.1038/s41588-022-01056-5.
Improving polygenic prediction in ancestrally diverse populations. Nat Genet. 2022. doi:10.1038/s41588-022-01054-7.
Single-cell genomic profiling of human dopamine neurons identifies a population that selectively degenerates in Parkinson's disease. Nat Neurosci. 2022;25(5):588-595. doi:10.1038/s41593-022-01061-1.
Longitudinal multi-omics analyses link gut microbiome dysbiosis with recurrent urinary tract infections in women. Nat Microbiol. 2022;7(5):630-639. doi:10.1038/s41564-022-01107-x.
Ancestry-inclusive dog genomics challenges popular breed stereotypes. Science. 2022;376(6592):eabk0639. doi:10.1126/science.abk0639.
Stepwise-edited, human melanoma models reveal mutations' effect on tumor and microenvironment. Science. 2022;376(6592):eabi8175. doi:10.1126/science.abi8175.
Protein Flexibility and Dissociation Pathway Differentiation Can Explain Onset Of Resistance Mutations in Kinases. Angew Chem Int Ed Engl. 2022. doi:10.1002/anie.202200983. .
Multimodal profiling of lung granulomas in macaques reveals cellular correlates of tuberculosis control. Immunity. 2022. doi:10.1016/j.immuni.2022.04.004.
High-Throughput Assay to Screen Small Molecules for Their Ability to Prevent Sickling of Red Blood Cells. ACS Omega. 2022;7(16):14009-14016. doi:10.1021/acsomega.2c00541.
Genome-wide pleiotropy analysis of coronary artery disease and pneumonia identifies shared immune pathways. Sci Adv. 2022;8(16):eabl4602. doi:10.1126/sciadv.abl4602.