Publications

Allele-specific expression changes dynamically during T cell activation in HLA and other autoimmune loci.

Gutierrez-Arcelus M, Baglaenko Y, Arora J, et al. Allele-specific expression changes dynamically during T cell activation in HLA and other autoimmune loci. Nat Genet. 2020. doi:10.1038/s41588-020-0579-4.

An immune-cell signature of bacterial sepsis.

Reyes M, Filbin MR, Bhattacharyya RP, et al. An immune-cell signature of bacterial sepsis. Nat Med. 2020. doi:10.1038/s41591-020-0752-4.

Identification of cancer driver genes based on nucleotide context.

Dietlein F, Weghorn D, Taylor-Weiner A, et al. Identification of cancer driver genes based on nucleotide context. Nat Genet. 2020. doi:10.1038/s41588-019-0572-y.

Immunological Fingerprints of Controllers Developing Neutralizing HIV-1 Antibodies.

Martin-Gayo E, Gao C, Chen HRong, et al. Immunological Fingerprints of Controllers Developing Neutralizing HIV-1 Antibodies. Cell Rep. 2020;30(4):984-996.e4. doi:10.1016/j.celrep.2019.12.087.

Partitioning of MLX-Family Transcription Factors to Lipid Droplets Regulates Metabolic Gene Expression.

Mejhert N, Kuruvilla L, Gabriel KR, et al. Partitioning of MLX-Family Transcription Factors to Lipid Droplets Regulates Metabolic Gene Expression. Mol Cell. 2020. doi:10.1016/j.molcel.2020.01.014.

Microscaled proteogenomic methods for precision oncology.

Satpathy S, Jaehnig EJ, Krug K, et al. Microscaled proteogenomic methods for precision oncology. Nat Commun. 2020;11(1):532. doi:10.1038/s41467-020-14381-2.

Genome-wide In Vivo CNS Screening Identifies Genes that Modify CNS Neuronal Survival and mHTT Toxicity.

Wertz MH, Mitchem MR, S Pineda S, et al. Genome-wide In Vivo CNS Screening Identifies Genes that Modify CNS Neuronal Survival and mHTT Toxicity. Neuron. 2020. doi:10.1016/j.neuron.2020.01.004.

Control of human hemoglobin switching by LIN28B-mediated regulation of BCL11A translation.

Basak A, Munschauer M, Lareau CA, et al. Control of human hemoglobin switching by LIN28B-mediated regulation of BCL11A translation. Nat Genet. 2020. doi:10.1038/s41588-019-0568-7.

Growth effects of N-acylethanolamines on gut bacteria reflect altered bacterial abundances in inflammatory bowel disease.

Fornelos N, Franzosa EA, Bishai J, et al. Growth effects of N-acylethanolamines on gut bacteria reflect altered bacterial abundances in inflammatory bowel disease. Nat Microbiol. 2020. doi:10.1038/s41564-019-0655-7.

Genome-wide CRISPR screen identifies host dependency factors for influenza A virus infection.

Li B, Clohisey SM, Chia BShao, et al. Genome-wide CRISPR screen identifies host dependency factors for influenza A virus infection. Nat Commun. 2020;11(1):164. doi:10.1038/s41467-019-13965-x.