Publications

ARPA-H: Accelerating biomedical breakthroughs.

Collins FS, Schwetz TA, Tabak LA, Lander ES. ARPA-H: Accelerating biomedical breakthroughs. Science. 2021;373(6551):165-167. doi:10.1126/science.abj8547.

Mass spectrometry-based HLA-II peptidomics combined with multi-omics will aid the development of future immunotherapies.

Taylor HB, Klaeger S, Clauser KR, et al. Mass spectrometry-based HLA-II peptidomics combined with multi-omics will aid the development of future immunotherapies. Mol Cell Proteomics. 2021:100116. doi:10.1016/j.mcpro.2021.100116.

Gene fusions create partner and collateral dependencies essential to cancer cell survival.

Gillani R, Seong BKyung A, Crowdis J, et al. Gene fusions create partner and collateral dependencies essential to cancer cell survival. Cancer Res. 2021. doi:10.1158/0008-5472.CAN-21-0791.

Reprogramming of the esophageal squamous carcinoma epigenome by SOX2 promotes ADAR1 dependence.

Wu Z, Zhou J, Zhang X, et al. Reprogramming of the esophageal squamous carcinoma epigenome by SOX2 promotes ADAR1 dependence. Nat Genet. 2021;53(6):881-894. doi:10.1038/s41588-021-00859-2.

Identification of a Novel Regulator of Clostridioides difficile Cortex Formation.

Touchette MH, de la Puebla HBenito, Feliciano CAlves, et al. Identification of a Novel Regulator of Clostridioides difficile Cortex Formation. mSphere. 2021:e0021121. doi:10.1128/mSphere.00211-21.

Human plasma proteomic profiles indicative of cardiorespiratory fitness.

Robbins JM, Peterson B, Schranner D, et al. Human plasma proteomic profiles indicative of cardiorespiratory fitness. Nat Metab. 2021. doi:10.1038/s42255-021-00400-z.

PANOPLY: a cloud-based platform for automated and reproducible proteogenomic data analysis.

Mani DR, Maynard M, Kothadia R, et al. PANOPLY: a cloud-based platform for automated and reproducible proteogenomic data analysis. Nat Methods. 2021. doi:10.1038/s41592-021-01176-6.

Advances in targeting 'undruggable' transcription factors with small molecules.

Henley MJ, Koehler AN. Advances in targeting 'undruggable' transcription factors with small molecules. Nat Rev Drug Discov. 2021. doi:10.1038/s41573-021-00199-0.

Cell-specific transcriptional control of mitochondrial metabolism by TIF1γ drives erythropoiesis.

Rossmann MP, Hoi K, Chan V, et al. Cell-specific transcriptional control of mitochondrial metabolism by TIF1γ drives erythropoiesis. Science. 2021;372(6543):716-721. doi:10.1126/science.aaz2740.

Extended-representation bisulfite sequencing of gene regulatory elements in multiplexed samples and single cells.

Shareef SJ, Bevill SM, Raman AT, et al. Extended-representation bisulfite sequencing of gene regulatory elements in multiplexed samples and single cells. Nat Biotechnol. 2021. doi:10.1038/s41587-021-00910-x.