Publications

Assessing optimal: inequalities in codon optimization algorithms.

Ranaghan MJ, Li JJ, Laprise DM, Garvie CW. Assessing optimal: inequalities in codon optimization algorithms. BMC Biol. 2021;19(1):36. doi:10.1186/s12915-021-00968-8.

The gut microbiome modulates the protective association between a Mediterranean diet and cardiometabolic disease risk.

Wang DD, Nguyen LH, Li Y, et al. The gut microbiome modulates the protective association between a Mediterranean diet and cardiometabolic disease risk. Nat Med. 2021. doi:10.1038/s41591-020-01223-3.

Genetic determinants of daytime napping and effects on cardiometabolic health.

Dashti HS, Daghlas I, Lane JM, et al. Genetic determinants of daytime napping and effects on cardiometabolic health. Nat Commun. 2021;12(1):900. doi:10.1038/s41467-020-20585-3.

Biomarkers to distinguish bacterial from viral pediatric clinical pneumonia in a malaria endemic setting.

Gillette MA, Mani DR, Uschnig C, et al. Biomarkers to distinguish bacterial from viral pediatric clinical pneumonia in a malaria endemic setting. Clin Infect Dis. 2021. doi:10.1093/cid/ciaa1843.

Dual functions of SPOP and ERG dictate androgen therapy responses in prostate cancer.

Bernasocchi T, Tekle GEl, Bolis M, et al. Dual functions of SPOP and ERG dictate androgen therapy responses in prostate cancer. Nat Commun. 2021;12(1):734. doi:10.1038/s41467-020-20820-x.

Regulatory genomic circuitry of human disease loci by integrative epigenomics.

Boix CA, James BT, Park YP, Meuleman W, Kellis M. Regulatory genomic circuitry of human disease loci by integrative epigenomics. Nature. 2021;590(7845):300-307. doi:10.1038/s41586-020-03145-z.

A wealth of discovery built on the Human Genome Project - by the numbers.

Gates AJ, Gysi DMorselli, Kellis M, Barabási A-L. A wealth of discovery built on the Human Genome Project - by the numbers. Nature. 2021;590(7845):212-215. doi:10.1038/d41586-021-00314-6.

Targeting oncoproteins with a positive selection assay for protein degraders.

Koduri V, Duplaquet L, Lampson BL, et al. Targeting oncoproteins with a positive selection assay for protein degraders. Sci Adv. 2021;7(6). doi:10.1126/sciadv.abd6263.

Noncanonical open reading frames encode functional proteins essential for cancer cell survival.

Prensner JR, Enache OM, Luria V, et al. Noncanonical open reading frames encode functional proteins essential for cancer cell survival. Nat Biotechnol. 2021. doi:10.1038/s41587-020-00806-2.

Regulation of purine metabolism connects KCTD13 to a metabolic disorder with autistic features.

Madison JM, Duong K, Vieux EF, et al. Regulation of purine metabolism connects KCTD13 to a metabolic disorder with autistic features. iScience. 2021;24(1):101935. doi:10.1016/j.isci.2020.101935.