Publications

Streamlined inactivation, amplification, and Cas13-based detection of SARS-CoV-2.

Arizti-Sanz J, Freije CA, Stanton AC, et al. Streamlined inactivation, amplification, and Cas13-based detection of SARS-CoV-2. Nat Commun. 2020;11(1):5921. doi:10.1038/s41467-020-19097-x.

Functional compensation precedes recovery of tissue mass following acute liver injury.

Walesky CM, Kolb KE, Winston CL, et al. Functional compensation precedes recovery of tissue mass following acute liver injury. Nat Commun. 2020;11(1):5785. doi:10.1038/s41467-020-19558-3.

A missense variant in confers risk for Crohn's disease by disrupting manganese homeostasis and intestinal barrier integrity.

Nakata T, Creasey EA, Kadoki M, et al. A missense variant in confers risk for Crohn's disease by disrupting manganese homeostasis and intestinal barrier integrity. Proc Natl Acad Sci U S A. 2020;117(46):28930-28938. doi:10.1073/pnas.2014742117.

Detection of Pathogenic Variants With Germline Genetic Testing Using Deep Learning vs Standard Methods in Patients With Prostate Cancer and Melanoma.

AlDubayan SH, Conway JR, Camp SY, et al. Detection of Pathogenic Variants With Germline Genetic Testing Using Deep Learning vs Standard Methods in Patients With Prostate Cancer and Melanoma. JAMA. 2020;324(19):1957-1969. doi:10.1001/jama.2020.20457.

Identification of Natural CRISPR Systems and Targets in the Human Microbiome.

Münch PC, Franzosa EA, Stecher B, McHardy AC, Huttenhower C. Identification of Natural CRISPR Systems and Targets in the Human Microbiome. Cell Host Microbe. 2020. doi:10.1016/j.chom.2020.10.010.

Acquired FGFR and FGF Alterations Confer Resistance to Estrogen Receptor (ER) Targeted Therapy in ER Metastatic Breast Cancer.

Mao P, Cohen O, Kowalski KJ, et al. Acquired FGFR and FGF Alterations Confer Resistance to Estrogen Receptor (ER) Targeted Therapy in ER Metastatic Breast Cancer. Clin Cancer Res. 2020;26(22):5974-5989. doi:10.1158/1078-0432.CCR-19-3958.

TFEB Transcriptional Responses Reveal Negative Feedback by BHLHE40 and BHLHE41.

Carey KL, Paulus GLC, Wang L, et al. TFEB Transcriptional Responses Reveal Negative Feedback by BHLHE40 and BHLHE41. Cell Rep. 2020;33(6):108371. doi:10.1016/j.celrep.2020.108371.

A Systematic Protein Turnover Map for Decoding Protein Degradation.

Christiano R, Arlt H, Kabatnik S, et al. A Systematic Protein Turnover Map for Decoding Protein Degradation. Cell Rep. 2020;33(6):108378. doi:10.1016/j.celrep.2020.108378.

COVID-19 and Cancer: Current Challenges and Perspectives.

Bakouny Z, Hawley JE, Choueiri TK, et al. COVID-19 and Cancer: Current Challenges and Perspectives. Cancer Cell. 2020;38(5):629-646. doi:10.1016/j.ccell.2020.09.018.

Lipid Droplets in Brown Adipose Tissue Are Dispensable for Cold-Induced Thermogenesis.

Chitraju C, Fischer AW, Farese RV, Walther TC. Lipid Droplets in Brown Adipose Tissue Are Dispensable for Cold-Induced Thermogenesis. Cell Rep. 2020;33(5):108348. doi:10.1016/j.celrep.2020.108348.