Pharmacogenomic agreement between two cancer cell line data sets.
Nature
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Abstract | Large cancer cell line collections broadly capture the genomic diversity of human cancers and provide valuable insight into anti-cancer drug response. Here we show substantial agreement and biological consilience between drug sensitivity measurements and their associated genomic predictors from two publicly available large-scale pharmacogenomics resources: The Cancer Cell Line Encyclopedia and the Genomics of Drug Sensitivity in Cancer databases. |
Year of Publication | 2015
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Journal | Nature
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Volume | 528
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Issue | 7580
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Pages | 84-7
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Date Published | 2015 Dec 03
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ISSN | 1476-4687
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URL | |
DOI | 10.1038/nature15736
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PubMed ID | 26570998
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Grant list | 086357 / Wellcome Trust / United Kingdom
102696 / Wellcome Trust / United Kingdom
1U54HG006097-01 / HG / NHGRI NIH HHS / United States
A16629 / Cancer Research UK / United Kingdom
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