Smart nanosystems: Bio-inspired technologies that interact with the host environment.

Proc Natl Acad Sci U S A
Authors
Keywords
Abstract

Nanoparticle technologies intended for human administration must be designed to interact with, and ideally leverage, a living host environment. Here, we describe smart nanosystems classified in two categories: (i) those that sense the host environment and respond and (ii) those that first prime the host environment to interact with engineered nanoparticles. Smart nanosystems have the potential to produce personalized diagnostic and therapeutic schema by using the local environment to drive material behavior and ultimately improve human health.

Year of Publication
2015
Journal
Proc Natl Acad Sci U S A
Volume
112
Issue
47
Pages
14460-6
Date Published
2015 Nov 24
ISSN
1091-6490
URL
DOI
10.1073/pnas.1508522112
PubMed ID
26598694
PubMed Central ID
PMC4664363
Links
Grant list
U54 CA151884 / CA / NCI NIH HHS / United States
P30 CA014051 / CA / NCI NIH HHS / United States
T32 GM007753 / GM / NIGMS NIH HHS / United States
U54CA151884 / CA / NCI NIH HHS / United States
P30-CA14051 / CA / NCI NIH HHS / United States
P30 ES002109 / ES / NIEHS NIH HHS / United States
Howard Hughes Medical Institute / United States
P30-ES002109 / ES / NIEHS NIH HHS / United States