Smart nanosystems: Bio-inspired technologies that interact with the host environment.
Proc Natl Acad Sci U S A
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Abstract | Nanoparticle technologies intended for human administration must be designed to interact with, and ideally leverage, a living host environment. Here, we describe smart nanosystems classified in two categories: (i) those that sense the host environment and respond and (ii) those that first prime the host environment to interact with engineered nanoparticles. Smart nanosystems have the potential to produce personalized diagnostic and therapeutic schema by using the local environment to drive material behavior and ultimately improve human health. |
Year of Publication | 2015
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Journal | Proc Natl Acad Sci U S A
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Volume | 112
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Issue | 47
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Pages | 14460-6
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Date Published | 2015 Nov 24
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ISSN | 1091-6490
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URL | |
DOI | 10.1073/pnas.1508522112
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PubMed ID | 26598694
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PubMed Central ID | PMC4664363
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Grant list | U54 CA151884 / CA / NCI NIH HHS / United States
P30 CA014051 / CA / NCI NIH HHS / United States
T32 GM007753 / GM / NIGMS NIH HHS / United States
U54CA151884 / CA / NCI NIH HHS / United States
P30-CA14051 / CA / NCI NIH HHS / United States
P30 ES002109 / ES / NIEHS NIH HHS / United States
Howard Hughes Medical Institute / United States
P30-ES002109 / ES / NIEHS NIH HHS / United States
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