|Publication Type||Journal Article|
|Year of Publication||2020|
|Authors||Spurr, LF, Touat, M, Taylor, AM, Dubuc, AM, Shih, J, Meredith, DM, Pisano, WV, Meyerson, ML, Ligon, KL, Cherniack, AD, Li, YY, Beroukhim, R|
|Date Published||2020 Nov 28|
SUMMARY: The expansion of targeted panel sequencing efforts has created opportunities for large-scale genomic analysis, but tools for copy-number quantification on panel data are lacking. We introduce ASCETS, a method for the efficient quantitation of arm and chromosome-level copy-number changes from targeted sequencing data.
AVAILABILITY: ASCETS is implemented in R and is freely available to non-commercial users on GitHub: https://github.com/beroukhim-lab/ascets, along with detailed documentation.
SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.