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Cancer Cell DOI:10.1016/j.ccell.2020.09.018

COVID-19 and Cancer: Current Challenges and Perspectives.

Publication TypeJournal Article
Year of Publication2020
AuthorsBakouny, Z, Hawley, JE, Choueiri, TK, Peters, S, Rini, BI, Warner, JL, Painter, CA
JournalCancer Cell
Date Published2020 11 09
KeywordsBetacoronavirus, Coronavirus Infections, COVID-19, Delivery of Health Care, Humans, Neoplasms, Pandemics, Pneumonia, Viral, SARS-CoV-2

Patients with cancer have been disproportionately affected by the COVID-19 pandemic. This effect has included the adverse outcomes in patients with cancer who develop COVID-19, the impact of the COVID-19 pandemic on the delivery of cancer care, and the severe disruption to cancer research. However, patients with cancer are a heterogeneous population, and recent studies have now documented factors that allow risk stratification of patients with cancer in order to optimize care. In this review, we highlight data at the intersection of COVID-19 and cancer, including the biological interplay between the two diseases and practical recommendations for the treatment of patients with cancer during the pandemic. We additionally discuss the potential long-lasting impact of the pandemic on cancer care due to its deleterious effect on cancer research, as well as biological insights from the cancer research community that could help develop novel therapies for all patients with COVID-19.


Alternate JournalCancer Cell
PubMed ID33049215
PubMed Central IDPMC7528740
Grant ListP30 CA068485 / CA / NCI NIH HHS / United States