Population Genetics, Evolutionary Genomics, and Genome-Wide Studies of Malaria: A View Across the International Centers of Excellence for Malaria Research.
Am J Trop Med Hyg
Authors | |
Keywords | |
Abstract | The study of the three protagonists in malaria-the Plasmodium parasite, the Anopheles mosquito, and the human host-is key to developing methods to control and eventually eliminate the disease. Genomic technologies, including the recent development of next-generation sequencing, enable interrogation of this triangle to an unprecedented level of scrutiny, and promise exciting progress toward real-time epidemiology studies and the study of evolutionary adaptation. We discuss the use of genomics by the International Centers of Excellence for Malaria Research, a network of field sites and laboratories in malaria-endemic countries that undertake cutting-edge research, training, and technology transfer in malarious countries of the world. |
Year of Publication | 2015
|
Journal | Am J Trop Med Hyg
|
Volume | 93
|
Issue | 3 Suppl
|
Pages | 87-98
|
Date Published | 2015 Sep
|
ISSN | 1476-1645
|
URL | |
DOI | 10.4269/ajtmh.15-0049
|
PubMed ID | 26259940
|
PubMed Central ID | PMC4574278
|
Links | |
Grant list | U19 AI089672 / AI / NIAID NIH HHS / United States
U19 AI089674 / AI / NIAID NIH HHS / United States
U19 AI089676 / AI / NIAID NIH HHS / United States
U19 AI089696 / AI / NIAID NIH HHS / United States
|