Population Genetics, Evolutionary Genomics, and Genome-Wide Studies of Malaria: A View Across the International Centers of Excellence for Malaria Research.

Am J Trop Med Hyg
Authors
Keywords
Abstract

The study of the three protagonists in malaria-the Plasmodium parasite, the Anopheles mosquito, and the human host-is key to developing methods to control and eventually eliminate the disease. Genomic technologies, including the recent development of next-generation sequencing, enable interrogation of this triangle to an unprecedented level of scrutiny, and promise exciting progress toward real-time epidemiology studies and the study of evolutionary adaptation. We discuss the use of genomics by the International Centers of Excellence for Malaria Research, a network of field sites and laboratories in malaria-endemic countries that undertake cutting-edge research, training, and technology transfer in malarious countries of the world.

Year of Publication
2015
Journal
Am J Trop Med Hyg
Volume
93
Issue
3 Suppl
Pages
87-98
Date Published
2015 Sep
ISSN
1476-1645
URL
DOI
10.4269/ajtmh.15-0049
PubMed ID
26259940
PubMed Central ID
PMC4574278
Links
Grant list
U19 AI089672 / AI / NIAID NIH HHS / United States
U19 AI089674 / AI / NIAID NIH HHS / United States
U19 AI089676 / AI / NIAID NIH HHS / United States
U19 AI089696 / AI / NIAID NIH HHS / United States