Impact of autoimmune risk alleles on the immune system.

Genome Med
Authors
Abstract

Genetic analyses of autoimmune diseases have revealed hundreds of disease-associated DNA variants, but the identity and function of the causal variants are understudied and warrant deeper mechanistic studies. Here, we highlight methods for deciphering how alleles that are associated with autoimmune disease alter the human immune system, and suggest strategies for future autoimmune genetic research.

Year of Publication
2015
Journal
Genome Med
Volume
7
Issue
1
Pages
57
Date Published
2015
URL
DOI
10.1186/s13073-015-0182-y
PubMed ID
26089985
PubMed Central ID
PMC4471922
Links