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Mol Psychiatry DOI:10.1038/s41380-020-0697-5

Genomic analysis of diet composition finds novel loci and associations with health and lifestyle.

Publication TypeJournal Article
Year of Publication2020
AuthorsS Meddens, FW, de Vlaming, R, Bowers, P, Burik, CAP, Linnér, RKarlsson, Lee, C, Okbay, A, Turley, P, Rietveld, CA, Fontana, MAlan, Ghanbari, M, Imamura, F, McMahon, G, van der Most, PJ, Voortman, T, Wade, KH, Anderson, EL, Braun, KVE, Emmett, PM, Esko, T, González, JR, de Jong, JCKiefte-, Langenberg, C, Luan, J'an, Muka, T, Ring, S, Rivadeneira, F, Snieder, H, van Rooij, FJA, Wolffenbuttel, BHR, Smith, GDavey, Franco, OH, Forouhi, NG, M Ikram, A, Uitterlinden, AG, van Vliet-Ostaptchouk, JV, Wareham, NJ, Cesarini, D, K Harden, P, Lee, JJ, Benjamin, DJ, Chow, CC, Koellinger, PD
Corporate Authors23andMe Research Team, EPIC- InterAct Consortium, LifeLines Cohort Study
JournalMol Psychiatry
Date Published2020 May 11
ISSN1476-5578
Abstract

We conducted genome-wide association studies (GWAS) of relative intake from the macronutrients fat, protein, carbohydrates, and sugar in over 235,000 individuals of European ancestries. We identified 21 unique, approximately independent lead SNPs. Fourteen lead SNPs are uniquely associated with one macronutrient at genome-wide significance (P 

DOI10.1038/s41380-020-0697-5
Pubmed

http://www.ncbi.nlm.nih.gov/pubmed/32393786?dopt=Abstract

Alternate JournalMol. Psychiatry
PubMed ID32393786