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Nucleic Acids Res DOI:10.1093/nar/gku1244

BioAssay Research Database (BARD): chemical biology and probe-development enabled by structured metadata and result types.

Publication TypeJournal Article
Year of Publication2015
AuthorsHowe, EA, De Souza, A, Lahr, DL, Chatwin, S, Montgomery, P, Alexander, BR, Nguyen, D-T, Cruz, Y, Stonich, DA, Walzer, G, Rose, JT, Picard, SC, Liu, Z, Rose, JN, Xiang, X, Asiedu, J, Durkin, D, Levine, J, Yang, JJ, Schürer, SC, Braisted, JC, Southall, N, Southern, MR, D Y Chung, T, Brudz, S, Tanega, C, Schreiber, SL, Bittker, JA, Guha, R, Clemons, PA
JournalNucleic Acids Res
Volume43
IssueDatabase issue
PagesD1163-70
Date Published2015 Jan
ISSN1362-4962
KeywordsBiological Assay, Data Mining, Databases, Factual, High-Throughput Screening Assays, Internet, Molecular Probes, Software
Abstract

BARD, the BioAssay Research Database (https://bard.nih.gov/) is a public database and suite of tools developed to provide access to bioassay data produced by the NIH Molecular Libraries Program (MLP). Data from 631 MLP projects were migrated to a new structured vocabulary designed to capture bioassay data in a formalized manner, with particular emphasis placed on the description of assay protocols. New data can be submitted to BARD with a user-friendly set of tools that assist in the creation of appropriately formatted datasets and assay definitions. Data published through the BARD application program interface (API) can be accessed by researchers using web-based query tools or a desktop client. Third-party developers wishing to create new tools can use the API to produce stand-alone tools or new plug-ins that can be integrated into BARD. The entire BARD suite of tools therefore supports three classes of researcher: those who wish to publish data, those who wish to mine data for testable hypotheses, and those in the developer community who wish to build tools that leverage this carefully curated chemical biology resource.

URLhttp://nar.oxfordjournals.org/cgi/pmidlookup?view=long&pmid=25477388
DOI10.1093/nar/gku1244
Pubmed

http://www.ncbi.nlm.nih.gov/pubmed/25477388?dopt=Abstract

Alternate JournalNucleic Acids Res.
PubMed ID25477388
PubMed Central IDPMC4383997
Grant ListU54-HG005032 / HG / NHGRI NIH HHS / United States