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Stroke; a journal of cerebral circulation DOI:10.1161/STROKEAHA.114.006072

Twelve-Single Nucleotide Polymorphism Genetic Risk Score Identifies Individuals at Increased Risk for Future Atrial Fibrillation and Stroke.

Publication TypeJournal Article
Year of Publication2014
AuthorsTada, H, Shiffman, D, Smith, JG, Sjögren, M, Lubitz, SA, Ellinor, PT, Louie, JZ, Catanese, JJ, Engström, G, Devlin, JJ, Kathiresan, S, Melander, O
JournalStroke; a journal of cerebral circulation
Date Published2014/08/14

Atrial fibrillation (AF) is prevalent and there is a clinical need for biomarkers to identify individuals at higher risk for AF. Fixed throughout a life course and assayable early in life, genetic biomarkers may meet this need. Here, we investigate whether multiple single nucleotide polymorphisms together as an AF genetic risk score (AF-GRS) can improve prediction of one's risk for AF.