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Circulation DOI:10.1161/CIRCULATIONAHA.114.009892

Integrating Genetic, Transcriptional, and Functional Analyses to Identify Five Novel Genes for Atrial Fibrillation.

Publication TypeJournal Article
Year of Publication2014
AuthorsSinner, MF, Tucker, NR, Lunetta, KL, Ozaki, K, Smith, JG, Trompet, S, Bis, JC, Lin, H, Chung, MK, Nielsen, JB, Lubitz, SA, Krijthe, BP, Magnani, JW, Ye, J, Gollob, MH, Tsunoda, T, Müller-Nurasyid, M, Lichtner, P, Peters, A, Dolmatova, E, Kubo, M, Smith, JD, Psaty, BM, Smith, NL, Jukema, JW, Chasman, DI, Albert, CM, Ebana, Y, Furukawa, T, MacFarlane, P, Harris, TB, Darbar, D, Dörr, M, Holst, AG, Svendsen, JH, Hofman, A, Uitterlinden, A, Gudnason, V, Isobe, M, Malik, R, Dichgans, M, Rosand, J, Van Wagoner, DR, METASTROKE, C, AFGen, C, Benjamin, EJ, Milan, DJ, Melander, O, Heckbert, S, Ford, I, Liu, Y, Barnard, J, Olesen, MS, Stricker, BH, Tanaka, T, Kääb, S, Ellinor, PT
JournalCirculation
Date Published2014/08/14
ISSN0009-7322
Abstract

-Atrial fibrillation (AF) affects over 30 million individuals worldwide and is associated with an increased risk of stroke, heart failure, and death. AF is highly heritable, yet the genetic basis for the arrhythmia remains incompletely understood.

URLhttp://circ.ahajournals.org/cgi/pmidlookup?view=long&pmid=25124494
DOI10.1161/CIRCULATIONAHA.114.009892
Pubmed

http://www.ncbi.nlm.nih.gov/pubmed/25124494?dopt=Abstract