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Cancer discovery DOI:10.1158/2159-8290.CD-14-0505

SPSB1 May Have MET Its Match during Breast Cancer Recurrence.

Publication TypeJournal Article
Year of Publication2014
AuthorsQin, Y, McAllister, SS
JournalCancer discovery
Volume4
Issue7
Pages760-1
Date Published2014/07/01
ISSN2159-8274
Abstract

Disease recurrence is the most common cause of death for patients with breast cancer, yet little is known about the molecular mechanisms underlying this process. Using inducible transgenic mouse model systems, Feng and colleagues identified SPSB1 as a determinant of breast cancer recurrence by virtue of its ability to protect tumor cells from apoptosis through c-MET activation. Cancer Discov; 4(7); 760-1. ©2014 AACR. See related article by Feng et al., p. 790.

URLhttp://cancerdiscovery.aacrjournals.org/cgi/pmidlookup?view=long&pmid=25002612
DOI10.1158/2159-8290.CD-14-0505
Pubmed

http://www.ncbi.nlm.nih.gov/pubmed/25002612?dopt=Abstract