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Cell DOI:10.1016/j.cell.2014.06.032

How far can mice carry autism research?

Publication TypeJournal Article
Year of Publication2014
AuthorsHyman, SE
JournalCell
Volume158
Issue1
Pages13-4
Date Published2014/07/03
ISSN0092-8674
Abstract

In the face of growing controversy about the utility of genetic mouse models of human disease, Rothwell et al. report on a shared mechanism by which two different neuroligin-3 mutations, associated with autism spectrum disorders in humans, produce an enhancement in motor learning. The open question is how much we can learn about human ills from such models.

URLhttp://linkinghub.elsevier.com/retrieve/pii/S0092-8674(14)00824-1
DOI10.1016/j.cell.2014.06.032
Pubmed

http://www.ncbi.nlm.nih.gov/pubmed/24995974?dopt=Abstract