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Cell DOI:10.1016/j.cell.2014.06.032

How far can mice carry autism research?

Publication TypeJournal Article
Year of Publication2014
AuthorsHyman, SE
JournalCell
Volume158
Issue1
Pages13-4
Date Published2014 Jul 03
ISSN1097-4172
KeywordsAnimals, Autistic Disorder, Cell Adhesion Molecules, Neuronal, Humans, Membrane Proteins, Nerve Tissue Proteins
Abstract

In the face of growing controversy about the utility of genetic mouse models of human disease, Rothwell et al. report on a shared mechanism by which two different neuroligin-3 mutations, associated with autism spectrum disorders in humans, produce an enhancement in motor learning. The open question is how much we can learn about human ills from such models.

URLhttp://linkinghub.elsevier.com/retrieve/pii/S0092-8674(14)00824-1
DOI10.1016/j.cell.2014.06.032
Pubmed

http://www.ncbi.nlm.nih.gov/pubmed/24995974?dopt=Abstract

Alternate JournalCell
PubMed ID24995974